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Sigara İçmesine Rağmen Oniki Yılda Progresyon Göstermeyen Pulmoner Langerhans Hücreli Histiyositoz Olgusu

Year 2017, Volume: 3 Issue: 2, 117 - 122, 01.01.2017

Fatih Üzer Ömer Özbudak Ahmet Gökhan Arslan

Abstract

Pulmoner langerhans hücreli histiositozis PLHH X; langerhans hücreli histiyositozisin alt grubu olup akciğerlerde langerhans hücre infiltrasyonunun görüldüğü, nedeni bilinmeyen nadir bir interstisyel akciğer hastalığıdır. PLHH prevalansı ile ilgili kesin bir veri yoktur. Bazı çalışmalarda prevalansı erkekler ve kadınlar için sırasıyla 0,27/100 000 ve 0,07/100 000 olarak tespit edilmiştir. Olguların büyük bir kısmının sigara içicisi olması patogenezinde sigaranın önemli bir yer tuttuğunu düşündürmektedir. Sigara içmesine rağmen 12 yılda progresyon göstermeyen nadir bir olguyu literatür eşliğinde sunuyoruz

Keywords

Erişkin Histiyositoz Pulmoner langerhans hücreli Radyoloji

References

  • Vassallo R, Ryu JH. Pulmonary Langerhans cell histiocytosis. Clin Chest Med 2004; 25: 561-71.
  • Tazi A, Soler P, Hance AJ. Adult pulmonary Langerhans’ cell histiocytosis. Thorax 2000; 55: 405-16.
  • Gülhan PY, Ekici A, Bulcun E, Ekici MS. Pulmonary Langerhans Cell Histiocytosis X: An analysis of four cases. Respir Case Rep 2013;2(3):106-11.
  • Watanabe R, Tatsumi K, Hashimoto S, Kuriyama T. Clinicoepidemiological features of pulmonary histiocytosis X. Intern Med 2001; 40: 998-1003.
  • Rao RN, Goodman LR, Tomashefski JF Jr. Smoking- related interstitial lung disease. Ann Diagn Pathol 2008; 12: 445-57.
  • Aguayo SM, Kane MA , King TE Jr, Schwarz MI, Grauer L, Miller YE. Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers. J Clin Invest 1989; 84: 1105-13.
  • Friedman PJ, Liebow AA, Sokoloff J. Eosinophilic granuloma of lung. Medicine 1981; 60: 385-96.
  • Baumgartner I, von Hochstetter A, Baumert B, Luetolf U, Follath F. Langerhans cell histiosytosis in adults. Med Pediatr Oncol 1997;28:9-14.
  • Sundar KM, Gosselin MV, Chung HL, Cahill BC. Pulmonary Langerhans cell histiocytosis: Emerging concepts in pathobiology, radiology, and clinical evolution of disease. Chest 2003; 123:1673-83.
  • Kulwiec EL, Lynch DA, Aguayo SM, Schwarz MI, King TE Jr. Imaging of pulmonary histiocytosis X. Radiographics 1992;12:515-26.
  • Demedts M, Wells AU, Anto JM, Costabel U, Hubbard R, Cullinan P, Slabbynck H, Rizzato G, Poletti V, Verbeken EK, Thomeer MJ, Kokkarinen J, Dalphin JC, Taylor AN. Interstitial lung diseases: An epidemiological overview. Eur Respir J 2001; 32:2-16.
  • Torre O, Harari S. The diagnosis of cystic lung diseases: A role for bronchoalveolar lavage and transbronchial biopsy? Respir Med 2010; 104: 81-5.
  • Tuncay E. Pulmoner Langerhans hücreli histiyositoz. In: Tabak L, Kumbasar ÖÖ editörler. Toraks Kitapları. Diffüz Parankimal Akciğer Hastalıkları. Sayı 2013; 17: 283-94.
  • Crausman RS, Jennıngs CA, Tuder RM, Ackerson LM, Irvın CG, King TE Jr. Pulmonary Histiocytosis X: Pulmonary function and exercise pathophysiology. Am J Respir Crit Care Med 1996; 53: 426-35.
  • Vashisht D, Muralidharan CG, Sivasubramanian R, Gupta MDK, Bharadwaj R, Sengupta P. Histiocytosis. Medical Journal Armed Forces India 2015;71: 197-200.
  • Hagmeyer L, Randerath W. Smoking-related interstitial lung disease. Deutsches Ärzteblatt International 2015; 112: 43-50.
  • Ahuja J, Kanne JP, Meyer CA, Pipavath SNJ, Schmidt RA, Swanson JO, Gdwin JD. Histiocytic disorders of the chest: Imaging findings. RadioGraphics 2015; 35:357-70.
  • Routy B, Hoang J, Gruber J. Pulmonary Langerhans Cell Histiocytosis with lytic bone involvement in an adult smoker: Regression following smoking cessation. Case Reports in Hematology 2015; 36-41.

Pulmonary Langerhans Cell Histiocytosis Case that not Shows any Progress although Smoking

Year 2017, Volume: 3 Issue: 2, 117 - 122, 01.01.2017

Fatih Üzer Ömer Özbudak Ahmet Gökhan Arslan

Abstract

Pulmonary Langerhans Cell Histiocytosis PLCH X, which is a subgroup of Langerhans Cell Histiocytosis, is an idiopathic interstitial lung disease in which Langerhans cell infiltration is seen in the lung. There is no certain data on the prevalence of PLHH. In some studies, the estimated prevalence was calculated as 0.27 and 0.07 per 100000 population in males and females respectively. Due to the large number of cases that are smokers, it is considered that the pathogenesis is related to smoking. We are presenting a rare case that has not progressed for 12 years despite smoking

Keywords

Adult Histiocytosis Pulmonary Langerhans cell Radiology

References

  • Vassallo R, Ryu JH. Pulmonary Langerhans cell histiocytosis. Clin Chest Med 2004; 25: 561-71.
  • Tazi A, Soler P, Hance AJ. Adult pulmonary Langerhans’ cell histiocytosis. Thorax 2000; 55: 405-16.
  • Gülhan PY, Ekici A, Bulcun E, Ekici MS. Pulmonary Langerhans Cell Histiocytosis X: An analysis of four cases. Respir Case Rep 2013;2(3):106-11.
  • Watanabe R, Tatsumi K, Hashimoto S, Kuriyama T. Clinicoepidemiological features of pulmonary histiocytosis X. Intern Med 2001; 40: 998-1003.
  • Rao RN, Goodman LR, Tomashefski JF Jr. Smoking- related interstitial lung disease. Ann Diagn Pathol 2008; 12: 445-57.
  • Aguayo SM, Kane MA , King TE Jr, Schwarz MI, Grauer L, Miller YE. Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers. J Clin Invest 1989; 84: 1105-13.
  • Friedman PJ, Liebow AA, Sokoloff J. Eosinophilic granuloma of lung. Medicine 1981; 60: 385-96.
  • Baumgartner I, von Hochstetter A, Baumert B, Luetolf U, Follath F. Langerhans cell histiosytosis in adults. Med Pediatr Oncol 1997;28:9-14.
  • Sundar KM, Gosselin MV, Chung HL, Cahill BC. Pulmonary Langerhans cell histiocytosis: Emerging concepts in pathobiology, radiology, and clinical evolution of disease. Chest 2003; 123:1673-83.
  • Kulwiec EL, Lynch DA, Aguayo SM, Schwarz MI, King TE Jr. Imaging of pulmonary histiocytosis X. Radiographics 1992;12:515-26.
  • Demedts M, Wells AU, Anto JM, Costabel U, Hubbard R, Cullinan P, Slabbynck H, Rizzato G, Poletti V, Verbeken EK, Thomeer MJ, Kokkarinen J, Dalphin JC, Taylor AN. Interstitial lung diseases: An epidemiological overview. Eur Respir J 2001; 32:2-16.
  • Torre O, Harari S. The diagnosis of cystic lung diseases: A role for bronchoalveolar lavage and transbronchial biopsy? Respir Med 2010; 104: 81-5.
  • Tuncay E. Pulmoner Langerhans hücreli histiyositoz. In: Tabak L, Kumbasar ÖÖ editörler. Toraks Kitapları. Diffüz Parankimal Akciğer Hastalıkları. Sayı 2013; 17: 283-94.
  • Crausman RS, Jennıngs CA, Tuder RM, Ackerson LM, Irvın CG, King TE Jr. Pulmonary Histiocytosis X: Pulmonary function and exercise pathophysiology. Am J Respir Crit Care Med 1996; 53: 426-35.
  • Vashisht D, Muralidharan CG, Sivasubramanian R, Gupta MDK, Bharadwaj R, Sengupta P. Histiocytosis. Medical Journal Armed Forces India 2015;71: 197-200.
  • Hagmeyer L, Randerath W. Smoking-related interstitial lung disease. Deutsches Ärzteblatt International 2015; 112: 43-50.
  • Ahuja J, Kanne JP, Meyer CA, Pipavath SNJ, Schmidt RA, Swanson JO, Gdwin JD. Histiocytic disorders of the chest: Imaging findings. RadioGraphics 2015; 35:357-70.
  • Routy B, Hoang J, Gruber J. Pulmonary Langerhans Cell Histiocytosis with lytic bone involvement in an adult smoker: Regression following smoking cessation. Case Reports in Hematology 2015; 36-41.
There are 18 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Fatih Üzer

Ömer Özbudak This is me

Ahmet Gökhan Arslan This is me

Publication Date January 1, 2017
Published in Issue Year 2017 Volume: 3 Issue: 2

Cite

APA Üzer, F., Özbudak, Ö., & Arslan, A. G. (2017). Sigara İçmesine Rağmen Oniki Yılda Progresyon Göstermeyen Pulmoner Langerhans Hücreli Histiyositoz Olgusu. Akdeniz Tıp Dergisi, 3(2), 117-122.