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Ozone Therapy and Its Effect on Cervical - Lumbar Disc Herniation

Year 2015, Volume: 15 Issue: 3, - , 25.08.2015
https://doi.org/10.17098/amj.88945

Abstract

Ozone consists of three oxygen atoms and is a colorless gas that is heavier than air with a pungent smell. Medical ozone is administered to the patient always in the form of a mixture of pure oxygen and pure ozone and in a certain concentration. The ozone gas, which can be used in many types of diseases, is preferred as its side effects are at minimal rate. There are different forms of medical ozone application. Cervical and lumbar pains are located in the first row of the reasons for applying to the clinics at daily practice. Lumbar and cervical disc herniation is one of the main causes of this pain. Ozone therapy is a complementary treatment which can be used along with conventional and surgical treatment for disc herniation. Ozone therapy allows a successful treatment for patients with cervical and lumbar pain due to its ease of implementation, high success rate in treatment and low side effect profile. Considering the negative effects of cervical and lumbar pain on quality of life and their prevalence in society, ozone therapy has an important place as an adjunctive therapy method to medical treatment, physical therapy and surgical treatment.

References

  • Dolphin S, Walker M. Healing accelerated by ionozone therapy. Physiotherapy 1979;65(3):81-2.
  • Borrelli E. Mechanism of action of oxygen ozone therapy in the treatment of disc herniation and low back pain. Acta Neurochir Suppl 2011;108:123-5.
  • Beck EG, Wasser G, Viebahn-Hänsler R. Der aktuelle Stand der Ozontherapie - Empirie und Grundlagenforschung. Forsch Komplementarmed 1998;5(2):61-75.
  • Viebahn-Haensler R, Olga Sonia León F, Ziad F. The Low-Dose Ozone Concept-Guidelines and Treatment Strategies. Ozone: Science & Engineering: The Journal of the International Ozone Association Ozone in Medicine 2012; 34(6):408-24.
  • Akkus I, Kalak S, Vural H. Leukocyte lipid peroxidation, superoxide dismutase, glutathione peroxidase and serum and leukocyte vitamin C levels of patients with type II diabetes mellitus. Clin Chem Acta 1996;344 (2):221–7.
  • León OS, Menéndez S, Merino N. Ozone oxidative preconditioning: a protection cellular damage by free radicals. Mediat Inflamm 1998;7:289– 94.
  • Aytaçoğlu S. Ozon Terapi Ankara Akupunktur ve Tamamlayıcı Tıp Dergisi 2014;2(1):31-6.
  • Karababa AO. Bel Ağrısı Epidemiyolojisi Türkiye Klinikleri J Neurosurg-Special Topics 2010;3:1-7.
  • Kızıl R. Servikal Disk Hernileri. Türkiye Klinikleri J PM&R-Special Topics 2009;2:35-43.
  • Alper S. Lomber Disk Hernileri. Türkiye Klinikleri J PM&R-Special Topics 2011;4:32-43.
  • D'Erme M, Scarchilli A, Artale AM, Pasquali Lasagni M. Ozone therapy in lumbar sciatic pain. Radiol Med. 1998; 95:21-4.
  • Muto M, Avella F. Percutaneous treatment of herniated lumbar disc by intradiscal oxygen-ozone injection. Interv Neuroradiol 1998;4:279-86.
  • Steppan J, Meaders T, Muto M, Murphy KJ. A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs. J Vasc Interv Radiol 2010;21:534-48.
  • Magalhaes FN, Dotta L, Sasse A, Teixera MJ, Fonoff ET. Ozone therapy as a treatment for low back pain secondary to herniated disc: a systematic review and meta-analysis of randomized controlled trials. Pain Physician 2012;15:115-29.
  • Zhang Y, Ma Y, Jiang J, Ding T, Wang J. Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone. J Back Musculoskelet Rehabil 2013;26:317-22.
  • Bocci V. Is it true that ozone is always toxic? The end of a dogma? Toxicol Appl Pharmacol 2006;216(3):493-504.
  • Alexandre A, Corò L, Azuelos A. et al. Intradiscal injection of oxygen-ozone gas mixture for the treatment of cervical disc herniations. Acta NeurochiSuppl 2005;92:79-82.
  • Oral A, Sindel D, Ketenci A. Evidence-Based Physical Medicine and Rehabilitation Strategies for Patients with Cervical Radiculopathy Due to Disc Herniation. Turk J Phys Med Rehab 2014;60:47-53
  • León Fernández OS, Pantoja M, Díaz Soto MT, Dranguet J, GarcíaInsua M, Viebhan-Hánsler R, et al. Ozone oxidative post-conditioning reduces oxidative protein damage in patients with disc hernia. Neurol Res 2012;34:59-67.

Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi

Year 2015, Volume: 15 Issue: 3, - , 25.08.2015
https://doi.org/10.17098/amj.88945

Abstract

Ozon, üç oksijen atomundan oluşan, keskin kokulu, havadan ağır renksiz bir gazdır. Medikal ozon ise hastaya daima saf ozon ve saf oksijenin karışımı şeklinde belli konsantrasyonlarda uygulanır. Pek çok hastalık türünde kullanılan ozon gazı, yan etkilerinin minimal oranda olması nedeniyle tercih sebebidir. Farklı medikal ozon uygulama şekilleri bulunmaktadır. Bel ve boyun ağrıları ise günlük pratikte polikliniğe başvuru nedenlerinin ilk sıralarında yer almaktadır. Lomber ve servikal disk hernileri bu ağrıların başlıca nedenlerinden biridir. Disk hernilerinde ozon tedavisi,  klasik tedavi ve cerrahi tedavi ile beraber kullanılabilen tamamlayıcı bir tedavi yöntemidir. Ozon tedavisi, uygulama kolaylığı, tedavideki başarı oranları, düşük yan etki profili sayesinde ağrılı bel ve boyun hastalarında başarılı bir tedaviye yardımcı olur. Disk hernileri sonucu ortaya çıkan bel ve boyun ağrılarının yaşam kalitesini oldukça kötü yönde etkilediği ve toplumdaki sıklığı göz önünde bulundurulduğunda, medikal tedavi, fizik tedavi ve cerrahi tedaviye yardımcı bir yöntem olarak ozon tedavisi önemli bir yer tutmaktadır.

References

  • Dolphin S, Walker M. Healing accelerated by ionozone therapy. Physiotherapy 1979;65(3):81-2.
  • Borrelli E. Mechanism of action of oxygen ozone therapy in the treatment of disc herniation and low back pain. Acta Neurochir Suppl 2011;108:123-5.
  • Beck EG, Wasser G, Viebahn-Hänsler R. Der aktuelle Stand der Ozontherapie - Empirie und Grundlagenforschung. Forsch Komplementarmed 1998;5(2):61-75.
  • Viebahn-Haensler R, Olga Sonia León F, Ziad F. The Low-Dose Ozone Concept-Guidelines and Treatment Strategies. Ozone: Science & Engineering: The Journal of the International Ozone Association Ozone in Medicine 2012; 34(6):408-24.
  • Akkus I, Kalak S, Vural H. Leukocyte lipid peroxidation, superoxide dismutase, glutathione peroxidase and serum and leukocyte vitamin C levels of patients with type II diabetes mellitus. Clin Chem Acta 1996;344 (2):221–7.
  • León OS, Menéndez S, Merino N. Ozone oxidative preconditioning: a protection cellular damage by free radicals. Mediat Inflamm 1998;7:289– 94.
  • Aytaçoğlu S. Ozon Terapi Ankara Akupunktur ve Tamamlayıcı Tıp Dergisi 2014;2(1):31-6.
  • Karababa AO. Bel Ağrısı Epidemiyolojisi Türkiye Klinikleri J Neurosurg-Special Topics 2010;3:1-7.
  • Kızıl R. Servikal Disk Hernileri. Türkiye Klinikleri J PM&R-Special Topics 2009;2:35-43.
  • Alper S. Lomber Disk Hernileri. Türkiye Klinikleri J PM&R-Special Topics 2011;4:32-43.
  • D'Erme M, Scarchilli A, Artale AM, Pasquali Lasagni M. Ozone therapy in lumbar sciatic pain. Radiol Med. 1998; 95:21-4.
  • Muto M, Avella F. Percutaneous treatment of herniated lumbar disc by intradiscal oxygen-ozone injection. Interv Neuroradiol 1998;4:279-86.
  • Steppan J, Meaders T, Muto M, Murphy KJ. A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs. J Vasc Interv Radiol 2010;21:534-48.
  • Magalhaes FN, Dotta L, Sasse A, Teixera MJ, Fonoff ET. Ozone therapy as a treatment for low back pain secondary to herniated disc: a systematic review and meta-analysis of randomized controlled trials. Pain Physician 2012;15:115-29.
  • Zhang Y, Ma Y, Jiang J, Ding T, Wang J. Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone. J Back Musculoskelet Rehabil 2013;26:317-22.
  • Bocci V. Is it true that ozone is always toxic? The end of a dogma? Toxicol Appl Pharmacol 2006;216(3):493-504.
  • Alexandre A, Corò L, Azuelos A. et al. Intradiscal injection of oxygen-ozone gas mixture for the treatment of cervical disc herniations. Acta NeurochiSuppl 2005;92:79-82.
  • Oral A, Sindel D, Ketenci A. Evidence-Based Physical Medicine and Rehabilitation Strategies for Patients with Cervical Radiculopathy Due to Disc Herniation. Turk J Phys Med Rehab 2014;60:47-53
  • León Fernández OS, Pantoja M, Díaz Soto MT, Dranguet J, GarcíaInsua M, Viebhan-Hánsler R, et al. Ozone oxidative post-conditioning reduces oxidative protein damage in patients with disc hernia. Neurol Res 2012;34:59-67.
There are 19 citations in total.

Details

Primary Language Turkish
Journal Section Reviews
Authors

Yasemin Korkut

Ceylan Ayada

Ümran Toru This is me

Publication Date August 25, 2015
Published in Issue Year 2015 Volume: 15 Issue: 3

Cite

APA Korkut, Y., Ayada, C., & Toru, Ü. (2015). Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi. Ankara Medical Journal, 15(3). https://doi.org/10.17098/amj.88945
AMA Korkut Y, Ayada C, Toru Ü. Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi. Ankara Med J. August 2015;15(3). doi:10.17098/amj.88945
Chicago Korkut, Yasemin, Ceylan Ayada, and Ümran Toru. “Ozon Tedavisi Ve Servikal - Lomber Disk Hernileri Üzerine Etkisi”. Ankara Medical Journal 15, no. 3 (August 2015). https://doi.org/10.17098/amj.88945.
EndNote Korkut Y, Ayada C, Toru Ü (August 1, 2015) Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi. Ankara Medical Journal 15 3
IEEE Y. Korkut, C. Ayada, and Ü. Toru, “Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi”, Ankara Med J, vol. 15, no. 3, 2015, doi: 10.17098/amj.88945.
ISNAD Korkut, Yasemin et al. “Ozon Tedavisi Ve Servikal - Lomber Disk Hernileri Üzerine Etkisi”. Ankara Medical Journal 15/3 (August 2015). https://doi.org/10.17098/amj.88945.
JAMA Korkut Y, Ayada C, Toru Ü. Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi. Ankara Med J. 2015;15. doi:10.17098/amj.88945.
MLA Korkut, Yasemin et al. “Ozon Tedavisi Ve Servikal - Lomber Disk Hernileri Üzerine Etkisi”. Ankara Medical Journal, vol. 15, no. 3, 2015, doi:10.17098/amj.88945.
Vancouver Korkut Y, Ayada C, Toru Ü. Ozon Tedavisi ve Servikal - Lomber Disk Hernileri Üzerine Etkisi. Ankara Med J. 2015;15(3).