Abstract
Tekrarlayan hışıltı şikâyeti ile
polikliniğe başvuran ve nazofaringeal sürüntüden etyolojik ajan olarak
Parainfluenza Tip 3 Virüsü elde edilen 8 yaşında kız hasta sunulmaktadır. Dört gündür
öksürük ve hırıltı şikâyeti ile dış merkeze götürülen hasta orada başlanan
tedaviye rağmen hırıltı şikâyetinin artması nedeni ile Çocuk Alerji ve
İmmünoloji Polikliniği’ne getirildi. Özgeçmişinde tekrarlayan hışıltıya yol
açmış çok sayıda bronşiolit tanısı ile salbutamol alma ve aralıklı montelukast
kullanım öyküsü mevcuttu. Hastanın yapılan fizik
muayenesinde bilateral sibilan ronküs, ekspiryum uzunluğu ve sukrepitan/kaba
ralleri olması nedeniyle ve ileri tetkik- tedavi için Çocuk Allerji ve
İmmünoloji Servisi’ ne yatışı yapıldı. Laboratuvar tetkiklerinde lökopeniyle
beraber lenfopeniye ek olarak monositoz gözlendi. Kliniğin düzelmesiyle
lökosit, lenfosit ve monosit sayıları normal sınırlara indi. Hastaya
salbutamol, ve ipratropium bromür nebül tedavisi başlandı. Nazofarenks sürüntüsünde
Parainfluenza Tip 3 virüsü izole edildi. Parainfluenza
virüs enfeksiyonları; çocukluk çağı tekrarlayan bronşioliti, astımı ve hışıltı
gibi kronik hava yolu hastalıklarının viral alevlenmelerinin önemli
nedenlerinden olup klinisyenler tarafından akılda tutulmalıdır.
Keywords
Supporting Institution
Yok
Project Number
Yok
Thanks
Yok
References
- 1. Fitzgerald DA, Kilham HA. Bronchiolitis: assessment and evidence-based management. Med J Aust. 2004;180(8):399-404.
- 2. Arden KE, McErlean P, Nissen MD, Sloots TP, Mackay IM. Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. J Med Virol. 2006;78(9):1232-40.
- 3. Reed G, Jewett PH, Thompson J, Tollefson S, Wright PF. Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children < 5 years old. J Infect Dis. 1997;175(4):807-13.
- 4. Waterson AP. Two kinds of myxovirus. Nature 1962;193:1163–4.5- Glezen WP, Denny FW. Epidemiology of acute lower respiratory disease in children. N Engl J Med 1973;288:498–505.
- 6. Fox TG, Christenson JC. Influenza and parainfluenza viral infections in children. Pediatr Rev. 2014; 35(6):217-27.
- 7. Karron RA, Wright PF, Newman FK, et al. A live human parainfluenza type 3 virus vaccine is attenuated and immunogenic in healthy infants and children. J Infect Dis 1995;172:1445–50.
- 8. Denny FW, Clyde WA Jr. Acute lower respiratory tract infections in nonhospitalized children. J Pediatr. 1986;108(5 Pt 1):635-46.
- 9. Tsukagoshi H, Ishioka T, Noda M, et al. Molecular epidemiology of respiratory viruses in virus-induced asthma. Front Microbiol. 2013;4:1–10.
- 10. Henrickson KJ. Parainfluenza viruses. Clin Microbiol Rev. 2003;16:242–64.
Abstract
An 8-year-old female patient was presented with a complaint of wheezing to the outpatient clinic and found out he had Parainfluenza Tip 3 Virus (PIV-3) as an etiological agent from nasopharyngeal swab. Patient was taken to paditaric allergy and immunology clinic while he did not respond to the therapy given by outside center and the wheezing complaint increased within last 4 days. There were many bronchiolitis attacks in the background requiring salbutamol and intermittently montelukast use. He was admitted to pediatric allergy and immunology service after physical examination showed bilateral sibilant rhonchi, expiration elongation and has subcrepitant /rough rales for further evaluation and therapy. Laboratory results show not only leukopenia but there are also lymphopenia plus monocytosis. Leukocyte, lymphocytes and monocytes numbers got normal after the patient clinical table improved. Salbutamol and ipratropium bromide nebul therapy was started. PIV-3 was isolated from her nasopharyngeal swab. Clinicians should keep in mind that viral infections such as Parainfluenza are important triggers for attacks of chronic airway diseases e.g. recurrent bronchiolitis, asthma and wheezing seen during childhood.
Keywords
Project Number
Yok
References
- 1. Fitzgerald DA, Kilham HA. Bronchiolitis: assessment and evidence-based management. Med J Aust. 2004;180(8):399-404.
- 2. Arden KE, McErlean P, Nissen MD, Sloots TP, Mackay IM. Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. J Med Virol. 2006;78(9):1232-40.
- 3. Reed G, Jewett PH, Thompson J, Tollefson S, Wright PF. Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children < 5 years old. J Infect Dis. 1997;175(4):807-13.
- 4. Waterson AP. Two kinds of myxovirus. Nature 1962;193:1163–4.5- Glezen WP, Denny FW. Epidemiology of acute lower respiratory disease in children. N Engl J Med 1973;288:498–505.
- 6. Fox TG, Christenson JC. Influenza and parainfluenza viral infections in children. Pediatr Rev. 2014; 35(6):217-27.
- 7. Karron RA, Wright PF, Newman FK, et al. A live human parainfluenza type 3 virus vaccine is attenuated and immunogenic in healthy infants and children. J Infect Dis 1995;172:1445–50.
- 8. Denny FW, Clyde WA Jr. Acute lower respiratory tract infections in nonhospitalized children. J Pediatr. 1986;108(5 Pt 1):635-46.
- 9. Tsukagoshi H, Ishioka T, Noda M, et al. Molecular epidemiology of respiratory viruses in virus-induced asthma. Front Microbiol. 2013;4:1–10.
- 10. Henrickson KJ. Parainfluenza viruses. Clin Microbiol Rev. 2003;16:242–64.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Project Number | Yok |
| Publication Date | December 31, 2019 |
| Acceptance Date | October 14, 2019 |
| Published in Issue | Year 2019 Volume: 3 Issue: 3 |
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