Research Article
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Year 2022, Volume: 8 Issue: 5, 612 - 618, 04.09.2022
https://doi.org/10.18621/eurj.982063

Abstract

References

  • 1. Reddan D. Patients at high risk of adverse events from intravenous contrast media after computed tomography examination. Eur J Radiol 2007;62:26-32.
  • 2. Rudnick MR, Goldfarb S. Pathogenesis of contrast-induced nephropathy experimental and clinical observations with an emphasis on the role of osmolalithy. Rev Cardiovasc Med 2003;4(Suppl 5):28-33.
  • 3. Wysowski DK, Nourjah P. Deaths attributed to X-ray contrast media on U.S. death certificates. AJR Am J Roentgenol 2006;186:613-5.
  • 4. Aspellin P, Aubry P, Fransson SG, Strasser R, Willenbrock R, Berg KJ. Nephrotoxic effects in high risk patients 
undergoing angiography. (NEFRIC study). N Eng J Med. 2003;348:491-9.
  • 5. Jorgensen AL. Contrast-induced nephropathy pathophysiology and preventive strategies. Crit Care Nurse 2013;33:37-46.
  • 6. Hassen GW, Hwang A, Liu LL, Mualim F, Sembo T, Tu TJ, et al. Follow up for emergency department patients after intravenous contrast and risk of nephropathy. West J Emerg Med 2014;15:276-81.
  • 7. Brendan J, Barrett M, Patrick SP. Contrast-induced nephropathy in rmergency department patients receiving abdominal contrast-enhanced computed tomography. Ann Emerg Med 2008;52:136.
  • 8. Cronin RE. Contrast-induced nephropathy: pathogenesis and prevention. Pediatr Nephrol 2009;25:191-204
  • 9. Rihal CS, Textor SC, Grill DE, Berger PB, Ting HH, Best PJ, et al. Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation 2002;105:2259-64.
  • 10. Thomsen H, Morcos S. Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol 2003;76:513-8.
  • 11. Nash K, Hafeez A, Hou S. Hospital acquired renal insufficiency. Am J Kidney Dis 2002;39:930-6.
  • 12. Mitchell AM, Kline JA. Contrast nephropathy following computed tomography angiography of the chest for pulmonary embolism in the emergency department. J Thromb Haemost 2007;5:50-4
  • 13. Kim KS, Kim K, Hwang SS, Jo YH, Lee CC, Kim TY, et al. Risk stratification nomogram for nephropathy after abdominal contrast-enhanced computed tomography. Am J Emerg Med 2011;29:412-7
  • 14. Gleeson, TG, Bulugahapitiya S. Contrast-induced nephropathy. Am J Roentgenol 2004;183:1673-89.
  • 15. Mohammed NM, Mahfouz A, Achkar K, Rafiye IM, Hajar R. Contrast-induced Nephropathy; Heart Views 2013;14:106-16.
  • 16. Kiski D, Stepper W, Breithardt G, Reinecke H. Impact of female gender on frequency of contrast medium-induced nephropathy: post hoc analysis of dialysis versus diuresis trial. J Womens Health (Larchmt) 2010;25:759-64.
  • 17. İşler Y, Özdınç Ş , Kaya H. Can NGAL be used as an early marker of contrast-ınduced nephropathy ın emergency department. Acta Medica Mediterranea 2018:34:1889-94.
  • 18. McCullough PA, Adam A, Becker CR, Davidson C, Lameire N, Stacul F, et al. CIN Consensus Working Panel. Risk prediction of contrast-induced nephropathy. Am J Cardiol 2006:98:27K-36K.
  • 19. Koruk R. Acil servise başvuran hastalarda kontrastlı tomografi sonrası opak nefropati olasılığı. Uzmanlık tezi. Eskişehir: Eskişehir Osmangazi Üniversitesi, 2017.
  • 20. Sadeghi HM, Stone GW, Grines CL, Mehran R, Dixon SR, Lansky AJ, et al. Impact of renal insufficiency in patients undergoing primary angioplasty for acute myocardial infarction. Circulation 2003;108:2769-75.
  • 21. Marenzi G, Lauri G, Campodonico J, Marana I, Assanelli E, De Metrio M, et al. Comparison of two hemofiltration protocols for prevention of contrast-induced nephropathy in high-risk patients. Am J Med 2006;119:155-62.
  • 22. Pannu N, Wiebe N, Tonelli M. Prophylaxis strategies for contrast-induced nephropathy. JAMA 2006;295:2765-79
  • 23. Mehran R, Aymong ED, Nikolsky E, Lasic Z, Lakovou I, Fahy M, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validitation. J Am Coll Cardiol 2004;44:1393-9
  • 24. Toprak O, Cirit M. Investigating the volume status before contrast nephropathy studies. Nephrol Dial Transplantat 2005;20:464.
  • 25. Cohen E, Kelly S, Edye M, Mitty H, Bromberg JS. MRI estimation of total renal volume demonstrates significant association with healty donor weight. Eur J Radiol 2009;283-7.
  • 26. Weisenbach J, Horvath M, Jeges S, Adamovich K, Huszár T. Normal percentiles of kidney size in children as measured by ultrasonography. Orv Hetil 2001;142:71-74
  • 27. Schmidt IM, Main KM, Damgaard IN, Mau C, Haavisto AM, Chellakooty M, et al. Kidney growth in 717 healthy children aged 0-18 months: A longitudinal cohort study. Pediatr Nephrol 2004;19:992-1003
  • 28. Şengül E, Binnetoğlu E, Yılmaz A. [The relationshıp between serum uric acid and glucose, HbA1c, lipid profile, body mass index and blood pressure in patients wıth chronic kidney diseas]e. DEÜ Tıp Fakültesi Dergisi 2011;25:163-8. [Article in Turkish]
  • 29. Gungoren F, Besli F, Tanriverdi Z, Demirbag R. Inferior vena cava assessment can predict contrast‐induced nephropathy in patients undergoing cardiac catheterization: A single‐center prospective study. Echocardiography 2018;35:1915-21.
  • 30. Kandemir H, Karadeniz M, Sarak T, Alp Ç. [The prevalence of contrast nephropathy in patients undergoing percutaneous coronary intervention in acute coronary syndrome]. J Health Sci Med 2018:1: 34-9. [Article in Turkish]
  • 31. Nikolsky E, Mehran R, Turcot D, Aymong ED, Mintz GS, Lasic Z, et al. Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention. Am J Cardiol 2004:94:300-5.
  • 32. Marenzi GC, Bartorelli AL, Lauri G, Assanelli E, Grazi M, Campodonico J, et al. Continuous veno-venous hemofiltration for the treatment of contrast-induced acute renal failure after percutaneous coronary interventions. Catheter Cardiovasc Interv 2003;58:59-64.
  • 33. Gruberg L, Mintz GS, Mehran R, Gangas G, Lansky AJ, Kent KM, et al. The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. J Am Coll Cardiol 2000;36:1542-8.
  • 34. Thomsen HS, Morcos SK. Contrast media and the kidney. European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol 2003;76:513-8.

Investigation of the relationship between contrast nephropathy development and body mass index in patients receiving contrast media in the emergency department

Year 2022, Volume: 8 Issue: 5, 612 - 618, 04.09.2022
https://doi.org/10.18621/eurj.982063

Abstract

Objectives: This study aims to investigate the risk factors in patients presenting to the emergency department, undergoing contrast-enhanced computed tomography (CT), and developing contrast-induced nephropathy (CIN) and whether there is a relationship between CIN and body mass index (BMI).

Methods: A total of 336 patients presenting to the emergency department between 15.3.2019 -31.12.2019 and underwent CT by administering intravenous (IV) contrast agent (CA) were prospectively analyzed. Patients' age, gender, chronic diseases, height, weight, BMI, and hospitalization or discharge information were recorded. Control creatinine was measured at 72nd and 120th hours. Patients who developed CIN were recorded.


Results:
The mean age of the patients was 57 years (min: 18-max: 96) and 56.5% were male. CIN developed in 6.5% of the patients. Congestive heart failure (CHF) was associated with the increased risk of CIN (p = 0.045). There was a significant increase in CIN risk in patients aged 40-70 years (p = 0.008). The risk of CIN development was increased with advanced age (p = 0.002). Dialysis was required in 13% of patients who developed CIN. There was no significant relationship between BMI and CIN development (p = 0.740).

Conclusions: We did not find a significant relationship between BMI and CIN. However, the risk of CIN development was higher in patients over 40 and especially in patients with CHF.

References

  • 1. Reddan D. Patients at high risk of adverse events from intravenous contrast media after computed tomography examination. Eur J Radiol 2007;62:26-32.
  • 2. Rudnick MR, Goldfarb S. Pathogenesis of contrast-induced nephropathy experimental and clinical observations with an emphasis on the role of osmolalithy. Rev Cardiovasc Med 2003;4(Suppl 5):28-33.
  • 3. Wysowski DK, Nourjah P. Deaths attributed to X-ray contrast media on U.S. death certificates. AJR Am J Roentgenol 2006;186:613-5.
  • 4. Aspellin P, Aubry P, Fransson SG, Strasser R, Willenbrock R, Berg KJ. Nephrotoxic effects in high risk patients 
undergoing angiography. (NEFRIC study). N Eng J Med. 2003;348:491-9.
  • 5. Jorgensen AL. Contrast-induced nephropathy pathophysiology and preventive strategies. Crit Care Nurse 2013;33:37-46.
  • 6. Hassen GW, Hwang A, Liu LL, Mualim F, Sembo T, Tu TJ, et al. Follow up for emergency department patients after intravenous contrast and risk of nephropathy. West J Emerg Med 2014;15:276-81.
  • 7. Brendan J, Barrett M, Patrick SP. Contrast-induced nephropathy in rmergency department patients receiving abdominal contrast-enhanced computed tomography. Ann Emerg Med 2008;52:136.
  • 8. Cronin RE. Contrast-induced nephropathy: pathogenesis and prevention. Pediatr Nephrol 2009;25:191-204
  • 9. Rihal CS, Textor SC, Grill DE, Berger PB, Ting HH, Best PJ, et al. Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation 2002;105:2259-64.
  • 10. Thomsen H, Morcos S. Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol 2003;76:513-8.
  • 11. Nash K, Hafeez A, Hou S. Hospital acquired renal insufficiency. Am J Kidney Dis 2002;39:930-6.
  • 12. Mitchell AM, Kline JA. Contrast nephropathy following computed tomography angiography of the chest for pulmonary embolism in the emergency department. J Thromb Haemost 2007;5:50-4
  • 13. Kim KS, Kim K, Hwang SS, Jo YH, Lee CC, Kim TY, et al. Risk stratification nomogram for nephropathy after abdominal contrast-enhanced computed tomography. Am J Emerg Med 2011;29:412-7
  • 14. Gleeson, TG, Bulugahapitiya S. Contrast-induced nephropathy. Am J Roentgenol 2004;183:1673-89.
  • 15. Mohammed NM, Mahfouz A, Achkar K, Rafiye IM, Hajar R. Contrast-induced Nephropathy; Heart Views 2013;14:106-16.
  • 16. Kiski D, Stepper W, Breithardt G, Reinecke H. Impact of female gender on frequency of contrast medium-induced nephropathy: post hoc analysis of dialysis versus diuresis trial. J Womens Health (Larchmt) 2010;25:759-64.
  • 17. İşler Y, Özdınç Ş , Kaya H. Can NGAL be used as an early marker of contrast-ınduced nephropathy ın emergency department. Acta Medica Mediterranea 2018:34:1889-94.
  • 18. McCullough PA, Adam A, Becker CR, Davidson C, Lameire N, Stacul F, et al. CIN Consensus Working Panel. Risk prediction of contrast-induced nephropathy. Am J Cardiol 2006:98:27K-36K.
  • 19. Koruk R. Acil servise başvuran hastalarda kontrastlı tomografi sonrası opak nefropati olasılığı. Uzmanlık tezi. Eskişehir: Eskişehir Osmangazi Üniversitesi, 2017.
  • 20. Sadeghi HM, Stone GW, Grines CL, Mehran R, Dixon SR, Lansky AJ, et al. Impact of renal insufficiency in patients undergoing primary angioplasty for acute myocardial infarction. Circulation 2003;108:2769-75.
  • 21. Marenzi G, Lauri G, Campodonico J, Marana I, Assanelli E, De Metrio M, et al. Comparison of two hemofiltration protocols for prevention of contrast-induced nephropathy in high-risk patients. Am J Med 2006;119:155-62.
  • 22. Pannu N, Wiebe N, Tonelli M. Prophylaxis strategies for contrast-induced nephropathy. JAMA 2006;295:2765-79
  • 23. Mehran R, Aymong ED, Nikolsky E, Lasic Z, Lakovou I, Fahy M, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validitation. J Am Coll Cardiol 2004;44:1393-9
  • 24. Toprak O, Cirit M. Investigating the volume status before contrast nephropathy studies. Nephrol Dial Transplantat 2005;20:464.
  • 25. Cohen E, Kelly S, Edye M, Mitty H, Bromberg JS. MRI estimation of total renal volume demonstrates significant association with healty donor weight. Eur J Radiol 2009;283-7.
  • 26. Weisenbach J, Horvath M, Jeges S, Adamovich K, Huszár T. Normal percentiles of kidney size in children as measured by ultrasonography. Orv Hetil 2001;142:71-74
  • 27. Schmidt IM, Main KM, Damgaard IN, Mau C, Haavisto AM, Chellakooty M, et al. Kidney growth in 717 healthy children aged 0-18 months: A longitudinal cohort study. Pediatr Nephrol 2004;19:992-1003
  • 28. Şengül E, Binnetoğlu E, Yılmaz A. [The relationshıp between serum uric acid and glucose, HbA1c, lipid profile, body mass index and blood pressure in patients wıth chronic kidney diseas]e. DEÜ Tıp Fakültesi Dergisi 2011;25:163-8. [Article in Turkish]
  • 29. Gungoren F, Besli F, Tanriverdi Z, Demirbag R. Inferior vena cava assessment can predict contrast‐induced nephropathy in patients undergoing cardiac catheterization: A single‐center prospective study. Echocardiography 2018;35:1915-21.
  • 30. Kandemir H, Karadeniz M, Sarak T, Alp Ç. [The prevalence of contrast nephropathy in patients undergoing percutaneous coronary intervention in acute coronary syndrome]. J Health Sci Med 2018:1: 34-9. [Article in Turkish]
  • 31. Nikolsky E, Mehran R, Turcot D, Aymong ED, Mintz GS, Lasic Z, et al. Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention. Am J Cardiol 2004:94:300-5.
  • 32. Marenzi GC, Bartorelli AL, Lauri G, Assanelli E, Grazi M, Campodonico J, et al. Continuous veno-venous hemofiltration for the treatment of contrast-induced acute renal failure after percutaneous coronary interventions. Catheter Cardiovasc Interv 2003;58:59-64.
  • 33. Gruberg L, Mintz GS, Mehran R, Gangas G, Lansky AJ, Kent KM, et al. The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. J Am Coll Cardiol 2000;36:1542-8.
  • 34. Thomsen HS, Morcos SK. Contrast media and the kidney. European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol 2003;76:513-8.
There are 34 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Original Articles
Authors

Mehmet Seyit Şerif Dilek This is me 0000-0003-1356-1125

Yeşim İşler 0000-0002-6389-5361

Halil Kaya 0000-0003-2005-6100

Melih Yüksel 0000-0002-0793-3693

Publication Date September 4, 2022
Submission Date August 13, 2021
Acceptance Date November 11, 2021
Published in Issue Year 2022 Volume: 8 Issue: 5

Cite

AMA Dilek MSŞ, İşler Y, Kaya H, Yüksel M. Investigation of the relationship between contrast nephropathy development and body mass index in patients receiving contrast media in the emergency department. Eur Res J. September 2022;8(5):612-618. doi:10.18621/eurj.982063

e-ISSN: 2149-3189 


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