Research Article
Year 2019,
Volume: 5 Issue: 1, 21 - 25, 04.04.2019
Abstract
Objectives: This study aims to examine patients with gastrointestinal system (GIS) bleeding and evaluate the appropriate treatment methods.
Materials and methods: This retrospective study included 164 patients (99 males, 65 females; mean age 66.87 years; range, 21 to 97 years) with GIS bleeding. Demographic characteristics, complaints, habits, duration of hospitalization, and medications used by patients were determined from the files. The effects of hemogram, biochemistry, coagulation, age, gender, and endoscopic findings on mortality were investigated. The effects of endoscopic findings and presence of additional diseases on blood transfusion and other treatment modalities, duration of hospitalization, and mortality were also investigated.
Results: Of the patients with GIS bleeding, 48.8% applied to our hospital with complaint of melena, 24.4% of melena and hematemesis, 15.8% of hematemesis, 6.1% of hematochezia, and 4.9% of syncope. Mean duration of hospitalization was 4.65±4.14 days. While endoscopy was performed in 98.2% of the patients, endoscopy could not be performed in 1.8% of the patients who could not be stabilized.
Conclusion: Bleeding control is important to reduce mortality in patients with GIS bleeding. We believe that particularly endoscopic intervention contributes positively in reducing such patients’ mortality and morbidity.
References
- 1. Adamopoulos AB, Baibas NM, Efstathiou SP, Tsioulos DI, Mitromaras AG, Tsami AA, et al. Differentiation between patients with acute upper gastrointestinal bleeding who need early urgent upper gastrointestinal endoscopy and those who do not. A prospective study. Eur J Gastroenterol Hepatol 2003;15:381-7. 2. Alkım H, amaz N. Akut üst gastrointestinal sistem kanaması. In: Özden A, ahin B, Yılmaz U, Soykan ‹, editörler. Gastroenteroloji. 1. Baskı. Ankara: Fersa Matbaacılık; 2002. s. 141-8. 3. Fleischer D. Etiology and prevalence of severe persistent upper gastrointestinal bleeding. Gastroenterology 1983;84:538-43. 4. Laine L, Peterson WL. Bleeding peptic ulcer. N Engl J Med 1994;331:717-27. 5. Feldman M, Friedman LS, Sleisenger MH. Sleisenger BF, Sleisenger MH, Feldman M. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 7th ed. Philadelphia: Saunders; 2011. 6. Rosen AM, Fleischer DE. Upper GI bleeding in the elderly: diagnosis and management. Geriatrics 1989;44:26-8. 7. Gilbert DA. Epidemiology of upper gastrointestinal bleeding. Gastrointest Endosc 1990;36:8-13. 8. Lanza F, Rack MF, Simon TJ, Lombardi A, Reyes R, Suryawanshi S. Effects of alendronate on gastric and duodenal mucosa. Am J Gastroenterol 1998;93:753-7. 9. Lau JY, Barkun A, Fan DM, Kuipers EJ, Yang YS, Chan FK. Challenges in the management of acute peptic ulcer bleeding. Lancet 2013;381:2033-43. 10. Lin HJ, Wang K, Perng CL, Chua RT, Lee FY, Lee CH, et al. Early or delayed endoscopy for patients with peptic ulcer bleeding. A prospective randomized study. J Clin Gastroenterol 1996;22:267-71. 11. Chan FK, Sung JJ, Suen R, Lee YT, Wu JC, Leung WK, et al. Does eradication of Helicobacter pylori impair healing of nonsteroidal anti-inflammatory drug associated bleeding peptic ulcers? A prospective randomized study. Aliment Pharmacol Ther 1998;12:1201-5. 12. Farooq FT, Lee MH, Das A, Dixit R, Wong RC. Clinical triage decision vs risk scores in predicting the need for endotherapy in upper gastrointestinal bleeding. Am J Emerg Med 2012;30:129-34. 13. Shorr RI, Ray WA, Daugherty JR, Griffin MR. Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease. Arch Intern Med 1993;153:1665-70. 14. Podolsky DK, Isselbacher K. Gastrointestinal diseases. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, et al., editors. Harrison’s Principles of Internal Medicine. 15th ed. New York: McGraw-Hill; 2004. p. 1649-65. 15. Ramírez F, Cifuentes C, Mavares J, Voso J, Monasterios W, Hinestrosa H, et al. Upper gastrointestinal hemorrhage. Prospective analysis of 741 cases. G E N 1993;47:139-44. [Abstract] 16. Lewis JD, Shin EJ, Metz DC. Characterization of gastrointestinal bleeding in severely ill hospitalized patients. Crit Care Med 2000;28:46-50. 17. Miño Fugarolas G, Jaramillo Esteban JL, Gálvez Calderón C, Carmona Ibáñez C, Reyes López A, De la Mata. An analysis of a general prospective series of 3270 upper digestive hemorrhages. Rev Esp Enferm Dig 1992;82:7-15. [Abstract] 18. Moshkowitz M, Brill S, Konikoff FM, Averbuch M, Arber N, Halpern Z. Additive deleterious effect of smoking on gastroduodenal pathology and clinical course in Helicobacter pylori-positive dyspeptic patients. Isr Med Assoc J 2000;2:892-5. 19. Aksöz K, Ünsal B, Akyol Z. Üst gastrointestinal kanamalı 2568 hastanın de¤erlendirilmesi. Turk J Gastroenterol 1995;6:262-4. 20. Okutur SK, Alkım C, Bes C, Akut üst gastrointestinal sistem kanamaları: 230 olgunun analizi. Akademik Gastroenteroloji Dergisi 2007;6:30-6. 21. Krämer SC, Görich J, Rilinger N, Siech M, Aschoff AJ, Vogel J, et al. Embolization for gastrointestinal hemorrhages. Eur Radiol 2000;10:802-5. 22. Thomopoulos KC, Vagenas KA, Vagianos CE, Margaritis VG, Blikas AP, Katsakoulis EC, et al. Changes in aetiology and clinical outcome of acute upper gastrointestinal bleeding during the last 15 years. Eur J Gastroenterol Hepatol 2004;16:177-82.
Year 2019,
Volume: 5 Issue: 1, 21 - 25, 04.04.2019
Abstract
References
- 1. Adamopoulos AB, Baibas NM, Efstathiou SP, Tsioulos DI, Mitromaras AG, Tsami AA, et al. Differentiation between patients with acute upper gastrointestinal bleeding who need early urgent upper gastrointestinal endoscopy and those who do not. A prospective study. Eur J Gastroenterol Hepatol 2003;15:381-7. 2. Alkım H, amaz N. Akut üst gastrointestinal sistem kanaması. In: Özden A, ahin B, Yılmaz U, Soykan ‹, editörler. Gastroenteroloji. 1. Baskı. Ankara: Fersa Matbaacılık; 2002. s. 141-8. 3. Fleischer D. Etiology and prevalence of severe persistent upper gastrointestinal bleeding. Gastroenterology 1983;84:538-43. 4. Laine L, Peterson WL. Bleeding peptic ulcer. N Engl J Med 1994;331:717-27. 5. Feldman M, Friedman LS, Sleisenger MH. Sleisenger BF, Sleisenger MH, Feldman M. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 7th ed. Philadelphia: Saunders; 2011. 6. Rosen AM, Fleischer DE. Upper GI bleeding in the elderly: diagnosis and management. Geriatrics 1989;44:26-8. 7. Gilbert DA. Epidemiology of upper gastrointestinal bleeding. Gastrointest Endosc 1990;36:8-13. 8. Lanza F, Rack MF, Simon TJ, Lombardi A, Reyes R, Suryawanshi S. Effects of alendronate on gastric and duodenal mucosa. Am J Gastroenterol 1998;93:753-7. 9. Lau JY, Barkun A, Fan DM, Kuipers EJ, Yang YS, Chan FK. Challenges in the management of acute peptic ulcer bleeding. Lancet 2013;381:2033-43. 10. Lin HJ, Wang K, Perng CL, Chua RT, Lee FY, Lee CH, et al. Early or delayed endoscopy for patients with peptic ulcer bleeding. A prospective randomized study. J Clin Gastroenterol 1996;22:267-71. 11. Chan FK, Sung JJ, Suen R, Lee YT, Wu JC, Leung WK, et al. Does eradication of Helicobacter pylori impair healing of nonsteroidal anti-inflammatory drug associated bleeding peptic ulcers? A prospective randomized study. Aliment Pharmacol Ther 1998;12:1201-5. 12. Farooq FT, Lee MH, Das A, Dixit R, Wong RC. Clinical triage decision vs risk scores in predicting the need for endotherapy in upper gastrointestinal bleeding. Am J Emerg Med 2012;30:129-34. 13. Shorr RI, Ray WA, Daugherty JR, Griffin MR. Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease. Arch Intern Med 1993;153:1665-70. 14. Podolsky DK, Isselbacher K. Gastrointestinal diseases. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, et al., editors. Harrison’s Principles of Internal Medicine. 15th ed. New York: McGraw-Hill; 2004. p. 1649-65. 15. Ramírez F, Cifuentes C, Mavares J, Voso J, Monasterios W, Hinestrosa H, et al. Upper gastrointestinal hemorrhage. Prospective analysis of 741 cases. G E N 1993;47:139-44. [Abstract] 16. Lewis JD, Shin EJ, Metz DC. Characterization of gastrointestinal bleeding in severely ill hospitalized patients. Crit Care Med 2000;28:46-50. 17. Miño Fugarolas G, Jaramillo Esteban JL, Gálvez Calderón C, Carmona Ibáñez C, Reyes López A, De la Mata. An analysis of a general prospective series of 3270 upper digestive hemorrhages. Rev Esp Enferm Dig 1992;82:7-15. [Abstract] 18. Moshkowitz M, Brill S, Konikoff FM, Averbuch M, Arber N, Halpern Z. Additive deleterious effect of smoking on gastroduodenal pathology and clinical course in Helicobacter pylori-positive dyspeptic patients. Isr Med Assoc J 2000;2:892-5. 19. Aksöz K, Ünsal B, Akyol Z. Üst gastrointestinal kanamalı 2568 hastanın de¤erlendirilmesi. Turk J Gastroenterol 1995;6:262-4. 20. Okutur SK, Alkım C, Bes C, Akut üst gastrointestinal sistem kanamaları: 230 olgunun analizi. Akademik Gastroenteroloji Dergisi 2007;6:30-6. 21. Krämer SC, Görich J, Rilinger N, Siech M, Aschoff AJ, Vogel J, et al. Embolization for gastrointestinal hemorrhages. Eur Radiol 2000;10:802-5. 22. Thomopoulos KC, Vagenas KA, Vagianos CE, Margaritis VG, Blikas AP, Katsakoulis EC, et al. Changes in aetiology and clinical outcome of acute upper gastrointestinal bleeding during the last 15 years. Eur J Gastroenterol Hepatol 2004;16:177-82.
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Details
| Primary Language | English |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | April 4, 2019 |
| Published in Issue | Year 2019 Volume: 5 Issue: 1 |
