Case Report
BibTex RIS Cite

Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?

Year 2022, Volume: 6 Issue: 3, 928 - 930, 29.09.2022

Betül Sargın

https://doi.org/10.30621/jbachs.1053935

Abstract

Co-existence of Familial Mediterranean Fever(FMF) and Paget’s disease (PD)is very rare. In this paper, we aimed to present a case of FMF patient presenting with PD. A 62-year old male patient admitted with complaint of chronic low back pain and weight loss. An increased uptake at pelvis which was reported as paget metabolic bone disease was identified in bone scintigraphy. An infusion of 5 mg of zoledronic acid, calcium and Vitamin D treatments were administered. Paget’s disease (PD)is a rare condition in patients with FMF. The co-existence of FMF and PD should not be forgotten.

Keywords

Familial Mediterranean Fever Paget Incidental Associated

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Almeida de Jesus A, Goldbach-Mansky R. Monogenic autoinflammatory diseases: concept and clinical manifestations. Clin. Immunol 2013;147:155-174.
  • 2. Portincasa P. Colchicine, Biologic Agents and More for the Treatment of Familial Mediterranean Fever. The Old, the New, and the Rare. Curr Med Chem 2016;23:60-86.
  • 3. Galson DL, Roodman GD. Pathobiology of Paget's disease of bone. J Bone Metabol 2014;21:85-98.
  • 4. Eekhoff EW, Karperien M, Houtsma D, et al. Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum 2004;50:1650-1654.
  • 5. Albagha OM. Genetics of Paget's disease of bone. Bonekey Rep 2015;4:756.
  • 6. Mor A, Shinar Y, Zaks N, et al. Evaluation of disease severity in familial Mediterranean fever. Semin Arthritis Rheum 2005;35:57-64.
  • 7. Appelman-Dijkstra NM, Papapoulos SE. Paget's disease of bone. Best Pract Res Clin Endocrinol Metab 2018;32:657-668.
  • 8. Singer FR, Bone HG, Hosking DJ, et al. Paget’s disease of bone: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2014;99:4408-4422.
  • 9. Josse RB, Hanley DA, Kendler D, et al. Diagnosis and treatment of Paget’s disease of bone. Clin Invest Med 2007;30:E210-E223.
  • 10. Cundy T, Maslowski K, Grey A, et al. Durability of response to zoledronate treatment and competing mortality in Paget's disease of bone. J Bone Miner Res 2017; 32:753-756.
  • 11. Walsh JP: Paget’s disease of bone. Med J Aust 2004;181:262-265.
  • 12. Chae JJ, Wood G, Richard K, et al. The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment. Blood 2008;112:1794-1803.

Year 2022, Volume: 6 Issue: 3, 928 - 930, 29.09.2022

Betül Sargın

https://doi.org/10.30621/jbachs.1053935

Abstract

Project Number

-

References

  • 1. Almeida de Jesus A, Goldbach-Mansky R. Monogenic autoinflammatory diseases: concept and clinical manifestations. Clin. Immunol 2013;147:155-174.
  • 2. Portincasa P. Colchicine, Biologic Agents and More for the Treatment of Familial Mediterranean Fever. The Old, the New, and the Rare. Curr Med Chem 2016;23:60-86.
  • 3. Galson DL, Roodman GD. Pathobiology of Paget's disease of bone. J Bone Metabol 2014;21:85-98.
  • 4. Eekhoff EW, Karperien M, Houtsma D, et al. Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum 2004;50:1650-1654.
  • 5. Albagha OM. Genetics of Paget's disease of bone. Bonekey Rep 2015;4:756.
  • 6. Mor A, Shinar Y, Zaks N, et al. Evaluation of disease severity in familial Mediterranean fever. Semin Arthritis Rheum 2005;35:57-64.
  • 7. Appelman-Dijkstra NM, Papapoulos SE. Paget's disease of bone. Best Pract Res Clin Endocrinol Metab 2018;32:657-668.
  • 8. Singer FR, Bone HG, Hosking DJ, et al. Paget’s disease of bone: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2014;99:4408-4422.
  • 9. Josse RB, Hanley DA, Kendler D, et al. Diagnosis and treatment of Paget’s disease of bone. Clin Invest Med 2007;30:E210-E223.
  • 10. Cundy T, Maslowski K, Grey A, et al. Durability of response to zoledronate treatment and competing mortality in Paget's disease of bone. J Bone Miner Res 2017; 32:753-756.
  • 11. Walsh JP: Paget’s disease of bone. Med J Aust 2004;181:262-265.
  • 12. Chae JJ, Wood G, Richard K, et al. The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment. Blood 2008;112:1794-1803.
There are 12 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Betül Sargın 0000-0002-9463-8413

Project Number -
Publication Date September 29, 2022
Submission Date January 5, 2022
Published in Issue Year 2022 Volume: 6 Issue: 3

Cite

APA Sargın, B. (2022). Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?. Journal of Basic and Clinical Health Sciences, 6(3), 928-930. https://doi.org/10.30621/jbachs.1053935
AMA Sargın B. Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?. JBACHS. September 2022;6(3):928-930. doi:10.30621/jbachs.1053935
Chicago Sargın, Betül. “Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?”. Journal of Basic and Clinical Health Sciences 6, no. 3 (September 2022): 928-30. https://doi.org/10.30621/jbachs.1053935.
EndNote Sargın B (September 1, 2022) Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?. Journal of Basic and Clinical Health Sciences 6 3 928–930.
IEEE B. Sargın, “Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?”, JBACHS, vol. 6, no. 3, pp. 928–930, 2022, doi: 10.30621/jbachs.1053935.
ISNAD Sargın, Betül. “Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?”. Journal of Basic and Clinical Health Sciences 6/3 (September 2022), 928-930. https://doi.org/10.30621/jbachs.1053935.
JAMA Sargın B. Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?. JBACHS. 2022;6:928–930.
MLA Sargın, Betül. “Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?”. Journal of Basic and Clinical Health Sciences, vol. 6, no. 3, 2022, pp. 928-30, doi:10.30621/jbachs.1053935.
Vancouver Sargın B. Familial Mediterranean Fever and Paget’s Disease: Incidental or Associated?. JBACHS. 2022;6(3):928-30.
 Download Cover Image