Abstract
Adamantinoma, nadir görülen düşük dereceli primer malign kemik tümörüdür ve genellikle tibia diyafizinde bulunur. Tümör lokal olarak agresiftir ve metastaz yapabilir. Kemoterapi ve radyoterapiye dirençli olduğu için asıl tedavi lezyonun geniş cerrahi sınırlarla total eksizyonudur. Radyolojik olarak diğer kemik lezyonlarından (osteofibröz displazi gibi) ayırt etmek zor olsa da bazı ayırt edici özellikleri vardır. Tipik bir vakanın bu sunumu ile radyologların dikkatini bu lezyona çekmeyi umuyoruz.
References
- Maier C. Ein primäres myelogenes Plattenepithelcarcinom der Ulna. Bruns’Beitr Klin Chir 1900; 26: 533.
- Jain D, Jain VK, Vasishta RK, Ranjan P, Kumar Y. Adamantinoma: A clinicopathological review and update. Diagnostic Pathol 2008; 3: 8.
- Fisher B. Primary adamantinoma of the tibia. Z Pathol 1913; 12: 422-41.
- Moon NF. Adamantinoma of the appendicular skeleton a statistical review of reported cases and inclusion of 10 new cases. Clin Orthop Relat Res (1976-2007) 1965; 43: 189-214.
- Kahn LB. Adamantinoma, osteofibrous dysplasia and differentiated adamantinoma. Skeletal Radiol. 2003; 32: 245-58.
- Judmaier W, Peer S, Krejzi T, Dessl A, Kühberger R. MR findings in tibial adamantinoma: a case report. Acta Radiologica 1998; 39: 276-8.
- Chen J, Zhang J. Adamantinoma filling the medullary space of the tibia: A case report. Radiol Case Rep 2019: 14: 1330–3.
- Mirra J. Adamantinoma and osteofibrous dysplasia. Bone Tumors. Clinical, Radiologic, and Pathologic Correlations 1989: 1217-31.
- Özger H, Alphan B. Management of rare, malignant bone tumors: diagnosis and treatment of adamantinoma and chordoma. TOTBİD Derg 2014; 13: 252–9.
- Keeney GL, Unni KK, Beabout JW, Pritchard DJ. Adamantinoma of long bones. a clinicopathologic study of 85 cases. Cancer 1989; 64: 730-7.
- Van Rijn R, Bras J, Schaap G, van den Berg H, Maas M. Adamantinoma in childhood: report of six cases and review of the literature. Pediatr Radiol 2006; 36: 1068-74.
- Khan MH, Darji R, Rao U, McGough R. Leg pain and swelling in a 22-year-old man. Clin Orthop Relat Res 2006; 448: 259-66.
- Hazelbag HM, Taminiau AH, Fleuren GJ, Hogendoorn PC. Adamantinoma of the long bones. A clinicopathological study of thirty-two patients with emphasis on histological subtype, precursor lesion, and biological behavior. J Bone Joint Surg Am 1994; 76: 1482-99.
- Devaney K. Dahlin’s Bone Tumors. General Aspects and Data on 11,087 Cases. Am J Surg Pathol 1996; 20: 1298.
Abstract
Adamantinoma is a rare low grade primary malignant bone tumor. The tumor is usually located in the diaphysis of tibia. The tumor is locally aggressive and can metastasis. As it is resistant to chemotherapy and radiotherapy, the main treatment is total excision of the lesion with wide surgical margins. Although it is difficult to distinguish from other bone lesions (such as osteofibrous dysplasia) radiologically, there are some helpful features. With this presentation of a typical case, we hope to draw the attention of radiologists to this lesion.
References
- Maier C. Ein primäres myelogenes Plattenepithelcarcinom der Ulna. Bruns’Beitr Klin Chir 1900; 26: 533.
- Jain D, Jain VK, Vasishta RK, Ranjan P, Kumar Y. Adamantinoma: A clinicopathological review and update. Diagnostic Pathol 2008; 3: 8.
- Fisher B. Primary adamantinoma of the tibia. Z Pathol 1913; 12: 422-41.
- Moon NF. Adamantinoma of the appendicular skeleton a statistical review of reported cases and inclusion of 10 new cases. Clin Orthop Relat Res (1976-2007) 1965; 43: 189-214.
- Kahn LB. Adamantinoma, osteofibrous dysplasia and differentiated adamantinoma. Skeletal Radiol. 2003; 32: 245-58.
- Judmaier W, Peer S, Krejzi T, Dessl A, Kühberger R. MR findings in tibial adamantinoma: a case report. Acta Radiologica 1998; 39: 276-8.
- Chen J, Zhang J. Adamantinoma filling the medullary space of the tibia: A case report. Radiol Case Rep 2019: 14: 1330–3.
- Mirra J. Adamantinoma and osteofibrous dysplasia. Bone Tumors. Clinical, Radiologic, and Pathologic Correlations 1989: 1217-31.
- Özger H, Alphan B. Management of rare, malignant bone tumors: diagnosis and treatment of adamantinoma and chordoma. TOTBİD Derg 2014; 13: 252–9.
- Keeney GL, Unni KK, Beabout JW, Pritchard DJ. Adamantinoma of long bones. a clinicopathologic study of 85 cases. Cancer 1989; 64: 730-7.
- Van Rijn R, Bras J, Schaap G, van den Berg H, Maas M. Adamantinoma in childhood: report of six cases and review of the literature. Pediatr Radiol 2006; 36: 1068-74.
- Khan MH, Darji R, Rao U, McGough R. Leg pain and swelling in a 22-year-old man. Clin Orthop Relat Res 2006; 448: 259-66.
- Hazelbag HM, Taminiau AH, Fleuren GJ, Hogendoorn PC. Adamantinoma of the long bones. A clinicopathological study of thirty-two patients with emphasis on histological subtype, precursor lesion, and biological behavior. J Bone Joint Surg Am 1994; 76: 1482-99.
- Devaney K. Dahlin’s Bone Tumors. General Aspects and Data on 11,087 Cases. Am J Surg Pathol 1996; 20: 1298.
Details
| Primary Language | English |
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| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | October 22, 2020 |
| Published in Issue | Year 2020 Volume: 3 Issue: 4 |
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Assoc. Prof. Alpaslan TANOĞLU (MD)
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