Case Report
BibTex RIS Cite

Nadir Görülen Bir Paraneoplastik Sendrom; Sweet Sendromu

Year 2021, Volume: 16 Issue: 2, 285 - 289, 07.07.2021

Dilek Güney Mehtap Şahin

https://doi.org/10.17517/ksutfd.811448

Abstract

Paraneoplastiksendrom; primer tümöre veya metastazlarına ait bir etki sebebi ile oluşmayan ancak tümörün varlığına bağımlı olarak gelişen belirti ve bulgulardan oluşan klinik tablo olarak adlandırılır. Paraneoplaziler varlığı bilinen bir tümörün seyri sırasında görülebildiği gibi, klinik olarak ortaya çıkmamış gizli bir tümörün ilk ve tek belirtisi olabilir ve bu sayede primer kanserin erken evrede tanınmasına yardımcı olabilmektedir. Akut febrilnötrofilik dermatoz olarak da bilinen Sweet Sendromu; ani başlangıçlı, ağrılı, inflamatuvar papül veya nodüllerden oluşmuş eritemli plaklar, ateş, eklem ağrısı, periferiklökositoz ve cildin dermis tabakasında yoğun nötrofil infiltrasyonu ile karakterize nadir görülen tekrarlayan inflamatuvar bir cilt hastalığıdır. Hastalık; inflamatuar bağırsak hastalığı, enfeksiyonlar, ilaçlara sekonder, malignite yesekonder (paraneoplastik) olarak gözlemlenebilmektedir.Bu yazımızda akut gelişen döküntü ve ateş şikayetleri ile başvurduğu hastanede Sweet Sendromu ön tanısı ile interne edilen yapılan etyolojik araştırmasında metastatik akciğer karsinoid tümör tanısı konulan 69 yaşında erkek hasta ile ilgili bir olgu sunmayı amaçladık.

Keywords

Sweet Sendromu Paraneoplastik Sendrom Akciğer Kanseri

References

  • 1. Brambilla E, Travis WD. World Cancer Report. In: Stewart BW, Wild CP (Eds), World Health Organization, Lyon 2014
  • 2. Pelosi, G., et al. "Unraveling tumor grading and genomic landscape in lung neuroendocrine tumors." Endocrine pathology 25.2 (2014): 151-164.
  • 3. Kaifi, JT., et al. "The diagnosis and treatment of bronchopulmonary carcinoid." Deutsches Ärzteblatt International 112.27-28 (2015): 479.
  • 4. Okutur, K. & Demir, G. "Paraneoplazi kavrami/Concept of Paraneoplasia." Turkderm 47.2 (2013): 59.
  • 5. Akyay, Ö. Z., Selek, A., & Tarkun, İ. "AKCİĞER KANSERİ, ENDOKRİNOPATİLER VE PARANEOPLASTİK SENDROMLAR." Bulletin of Thoracic Surgery/Toraks Cerrahisi Bülteni (2015): 9.4.
  • 6. WOLFF, K., et al. Fitzpatrick’s dermatology in general medicine, 2 volumes. Transplantation, 2008, 85.654.
  • 7. COHEN, P.R. Sweet's syndrome–a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet journal of rare diseases, 2007, 2.1: 34.
  • 8. GÜNEŞ BILGILI, S., et al. Sweet syndrome: clinical and laboratory findings of 31 cases. TURKDERM-Archieves of The Turkish Dermatology and Venerology, 2013, 47.1: 33-38.
  • 9. ÖZUĞUZ, P., et al. Elin nötrofilik dermatozu. Pamukkale Tıp Dergisi, 2: 147-150..
  • 10. CHUNG, VQ., et al. Clinical and pathologic findings of paraneoplastic dermatoses. Journal of the American Academy of Dermatology, 2006, 54.5: 745-762.
  • 11. Stone SP, Buescher LS. Life-threatening paraneoplastic cutaneous syndromes. Clinics in dermatology, 2005, 23.3: 301-306.
  • 12. Schiller M., et al. Dermatomyositis associated with malignant melanoma—A marker of poor prognosis?. Journal of the American Academy of Dermatology, 2006, 54.2: 221-226.
  • 13. AKI, T., et al.Büllöz lezyonların eşlik ettiği idiyopatikSweetsendromu: Olgu tartışması. Journal of Inonu University Medical Faculty, 2004, 11(4), 255-258.
  • 14. Yavuz E, Yeşilova Y, Sula B. Paraneoplastik Dermatozlar. MedBull Haseki 2010;48:61-67
  • 15. Sweet RD An acutefebrileneutrophilicdermatosis. British Journal of Dermatology 1964, 76: 349–356.
  • 16. Thompson DF and Montarella KE Drug-inducedSweet’ssyndrome. Annals of Pharmacotherapy 2007, 41:802–811.
  • 17. GUARNERI, C., et al. Sweet's syndrome and erythema nodosum in patient with cystitis caused by Klebsiella pneumoniae. Giornale italiano di dermatologia e venereologia, 2002, 137.5: 331-333.
  • 18. Vignon-Pennamen MD., The extracutaneous involvement in the neutrophilic dermatoses. Clinics in dermatology, 2000, 18.3: 339-347.
  • 19. Von den Driesch P. Sweet's syndrome (acute febrile neutrophilic dermatosis). Journal of the American Academy of Dermatology, 1994, 31.4: 535-556.
  • 20. Orfanos-Garbe, Therapie der Hautkrankheiten, 2. Auflage, 2002, S. 447-448
  • 21. Villarreal-Villarreal, C. D.,Ocampo-Candiani, J., &Villarreal-Martínez, A. Sweetsyndrome: a review and update. ActasDermo-Sifiliográficas (English Edition), 2016. 107(5), 369-378.
  • 22. Oner, F. et al. Akut FebrilNotrofilikDermatoz (Sweet Sendromu). istanbul Tip Dergisi 2005:2;47-49
  • 23. ARAI, H., et al. Lung cancer associated with Sweet’s syndrome: Report of a case. Surgery today, 2008, 38.7: 639-643.
  • 24. FRANCO, M., et al. Síndrome de Sweet asociado a neoplasias. Anais brasileiros de dermatologia, 2006, 81.5: 473-482.
  • 25. TEWARI, A., et al. Sweet syndrome preceding a carcinoid lung tumor and multiple myeloma. Cutis, 2013, 92.1: E1-E1.
  • 26. Yamamoto, T., Furuse, Y., & Nishioka, K., Sweet's syndrome with small cell carcinoma of the lung. The Journal of Dermatology, 1994, 21.2: 125-127.
  • 27. NIELSEN, I., et al. Sweet's syndrome and malignancy: report of the first case associated with adenocarcinoma of the lung. Lung cancer, 1993, 10.1-2: 95-99.
  • 28. Vrancken, A., Verbeken, E., & Nackaerts, K. ,Skin lesions in a lung cancer patient. Acta Clinica Belgica, 2015, 70.3: 231-232.
  • 29. VAN, AD, et al. Sweet's syndrome associated with squamous cell bronchial carcinoma. Neutrophilic dermatosis and non-small cell lung cancer. Revue des maladies respiratoires, 2007, 24.1: 77-80.
  • 30. AHANGARI, D., et al. Syndrome de Sweet chez une patiente traitée par erlotinib pour un adénocarcinome bronchique. In: Annales de Dermatologie et de Vénéréologie. Elsevier Masson, 2020. p. 202-206. 31. CUNY, R. A case from practice (249). Sweet syndrome in triple carcinoma. Schweizerische Rundschau fur Medizin Praxis= Revue suisse de medecine Praxis, 1992, 81.35: 1030.
  • 32. PELOSI G., et al. Unraveling tumor grading and genomic landscape in lung neuroendocrine tumors. Endocrine pathology, 2014, 25.2: 151-164.
  • 33. Noel-Savina, E.,&Descourt, R., Focus on treatment of lungcarcinoidtumor. OncoTargets and therapy, 2013, 6:1533.
  • 34. FINK, G., et al. Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from the literature. Chest, 2001, 119.6: 1647-1651.

A Rare Paraneoplastic Syndrome; Sweet Syndrome

Year 2021, Volume: 16 Issue: 2, 285 - 289, 07.07.2021

Dilek Güney Mehtap Şahin

https://doi.org/10.17517/ksutfd.811448

Abstract

Paraneoplastic syndrome; It is called a clinical Picture that does not ocur due to an effect of the primary tumor or its metastases, but consists of signs and symptoms that develop depending on the presence of the tumor. Paraneoplasias can be seenduring the course of a tumorwith a known presence, and may be the first and onlysymptom of a hiddentumorthat has not emergedclinically, thushelping to identifyprimarycancer at an earlystage. Sweet'sSyndrome, alsoknown as acutefebrileneutrophilicdermatosis; It is a rare, recurrentinflammatory skin diseasecharacterizedbysuddenonset, painful, inflammatorypapulesornoduleswitherythematousplaques, fever, jointpain, peripheralleukocytosis and intenseneutrophilinfiltration in the dermislayer of the skin. Disease; It can be observed as inflammatoryboweldisease, infections, secondary to drugs, secondary to malignancy (paraneoplastic). In this article, weaimed to present a case of a 69-year-old malepatientwhowasdiagnosedwithmetastaticlungcarcinoidtumor in the etiologicalinvestigationperformedwith the pre-diagnosis of SweetSyndrome in the hospitalwhere he presentedwithcomplaints of acuterash and fever.

Keywords

Sweet Syndrome Paraneoplastic Syndrome Lung Cancer

References

  • 1. Brambilla E, Travis WD. World Cancer Report. In: Stewart BW, Wild CP (Eds), World Health Organization, Lyon 2014
  • 2. Pelosi, G., et al. "Unraveling tumor grading and genomic landscape in lung neuroendocrine tumors." Endocrine pathology 25.2 (2014): 151-164.
  • 3. Kaifi, JT., et al. "The diagnosis and treatment of bronchopulmonary carcinoid." Deutsches Ärzteblatt International 112.27-28 (2015): 479.
  • 4. Okutur, K. & Demir, G. "Paraneoplazi kavrami/Concept of Paraneoplasia." Turkderm 47.2 (2013): 59.
  • 5. Akyay, Ö. Z., Selek, A., & Tarkun, İ. "AKCİĞER KANSERİ, ENDOKRİNOPATİLER VE PARANEOPLASTİK SENDROMLAR." Bulletin of Thoracic Surgery/Toraks Cerrahisi Bülteni (2015): 9.4.
  • 6. WOLFF, K., et al. Fitzpatrick’s dermatology in general medicine, 2 volumes. Transplantation, 2008, 85.654.
  • 7. COHEN, P.R. Sweet's syndrome–a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet journal of rare diseases, 2007, 2.1: 34.
  • 8. GÜNEŞ BILGILI, S., et al. Sweet syndrome: clinical and laboratory findings of 31 cases. TURKDERM-Archieves of The Turkish Dermatology and Venerology, 2013, 47.1: 33-38.
  • 9. ÖZUĞUZ, P., et al. Elin nötrofilik dermatozu. Pamukkale Tıp Dergisi, 2: 147-150..
  • 10. CHUNG, VQ., et al. Clinical and pathologic findings of paraneoplastic dermatoses. Journal of the American Academy of Dermatology, 2006, 54.5: 745-762.
  • 11. Stone SP, Buescher LS. Life-threatening paraneoplastic cutaneous syndromes. Clinics in dermatology, 2005, 23.3: 301-306.
  • 12. Schiller M., et al. Dermatomyositis associated with malignant melanoma—A marker of poor prognosis?. Journal of the American Academy of Dermatology, 2006, 54.2: 221-226.
  • 13. AKI, T., et al.Büllöz lezyonların eşlik ettiği idiyopatikSweetsendromu: Olgu tartışması. Journal of Inonu University Medical Faculty, 2004, 11(4), 255-258.
  • 14. Yavuz E, Yeşilova Y, Sula B. Paraneoplastik Dermatozlar. MedBull Haseki 2010;48:61-67
  • 15. Sweet RD An acutefebrileneutrophilicdermatosis. British Journal of Dermatology 1964, 76: 349–356.
  • 16. Thompson DF and Montarella KE Drug-inducedSweet’ssyndrome. Annals of Pharmacotherapy 2007, 41:802–811.
  • 17. GUARNERI, C., et al. Sweet's syndrome and erythema nodosum in patient with cystitis caused by Klebsiella pneumoniae. Giornale italiano di dermatologia e venereologia, 2002, 137.5: 331-333.
  • 18. Vignon-Pennamen MD., The extracutaneous involvement in the neutrophilic dermatoses. Clinics in dermatology, 2000, 18.3: 339-347.
  • 19. Von den Driesch P. Sweet's syndrome (acute febrile neutrophilic dermatosis). Journal of the American Academy of Dermatology, 1994, 31.4: 535-556.
  • 20. Orfanos-Garbe, Therapie der Hautkrankheiten, 2. Auflage, 2002, S. 447-448
  • 21. Villarreal-Villarreal, C. D.,Ocampo-Candiani, J., &Villarreal-Martínez, A. Sweetsyndrome: a review and update. ActasDermo-Sifiliográficas (English Edition), 2016. 107(5), 369-378.
  • 22. Oner, F. et al. Akut FebrilNotrofilikDermatoz (Sweet Sendromu). istanbul Tip Dergisi 2005:2;47-49
  • 23. ARAI, H., et al. Lung cancer associated with Sweet’s syndrome: Report of a case. Surgery today, 2008, 38.7: 639-643.
  • 24. FRANCO, M., et al. Síndrome de Sweet asociado a neoplasias. Anais brasileiros de dermatologia, 2006, 81.5: 473-482.
  • 25. TEWARI, A., et al. Sweet syndrome preceding a carcinoid lung tumor and multiple myeloma. Cutis, 2013, 92.1: E1-E1.
  • 26. Yamamoto, T., Furuse, Y., & Nishioka, K., Sweet's syndrome with small cell carcinoma of the lung. The Journal of Dermatology, 1994, 21.2: 125-127.
  • 27. NIELSEN, I., et al. Sweet's syndrome and malignancy: report of the first case associated with adenocarcinoma of the lung. Lung cancer, 1993, 10.1-2: 95-99.
  • 28. Vrancken, A., Verbeken, E., & Nackaerts, K. ,Skin lesions in a lung cancer patient. Acta Clinica Belgica, 2015, 70.3: 231-232.
  • 29. VAN, AD, et al. Sweet's syndrome associated with squamous cell bronchial carcinoma. Neutrophilic dermatosis and non-small cell lung cancer. Revue des maladies respiratoires, 2007, 24.1: 77-80.
  • 30. AHANGARI, D., et al. Syndrome de Sweet chez une patiente traitée par erlotinib pour un adénocarcinome bronchique. In: Annales de Dermatologie et de Vénéréologie. Elsevier Masson, 2020. p. 202-206. 31. CUNY, R. A case from practice (249). Sweet syndrome in triple carcinoma. Schweizerische Rundschau fur Medizin Praxis= Revue suisse de medecine Praxis, 1992, 81.35: 1030.
  • 32. PELOSI G., et al. Unraveling tumor grading and genomic landscape in lung neuroendocrine tumors. Endocrine pathology, 2014, 25.2: 151-164.
  • 33. Noel-Savina, E.,&Descourt, R., Focus on treatment of lungcarcinoidtumor. OncoTargets and therapy, 2013, 6:1533.
  • 34. FINK, G., et al. Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from the literature. Chest, 2001, 119.6: 1647-1651.
There are 33 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Olgu Sunumları
Authors

Dilek Güney 0000-0003-1416-8122

Mehtap Şahin 0000-0001-8495-2858

Publication Date July 7, 2021
Submission Date October 16, 2020
Acceptance Date November 25, 2020
Published in Issue Year 2021 Volume: 16 Issue: 2

Cite

AMA Güney D, Şahin M. Nadir Görülen Bir Paraneoplastik Sendrom; Sweet Sendromu. KSU Medical Journal. July 2021;16(2):285-289. doi:10.17517/ksutfd.811448
 Download Cover Image