Abstract
Malabsorbsiyon, gastroenterit, hipermotilite gibi etiyolojide enfeksiyöz ve non-enfeksiyöz nedenlerin olduğu ishal pek çok tıp disiplininin yönettiği klinik durumlarda görülebilen ortak bir semptomdur. İshal hayatı tehdit eden klinik durumlardan basit sulu dışkılamaya kadar geniş bir spektruma dağılmıştır. Genellikle, altta yatan hastalığı tedavi etmek ve uygun diyet müdahalelerini uygulamak ishali kontrol etmek için yeterlidir. Bununla birlikte, bu tür önlemler yetersiz olduğunda, geçiş süresini uzatmak ve sıvı ve elektrolit emilimini arttırmak için loperamid veya difenoksilat atropin kombinasyonu kullanılabilecek ajanlardır.
Keywords
References
- 1. Awouters F, Niemegeers CJ, Janssen PA. Pharmacology of antidiarrheal drugs. Annu Rev Pharmacol Toxicol. 1983;23:279-301. doi: 10.1146/annurev.pa.23.040183.001431. PMID: 6307123.
- 2. Stern J, Ippoliti C. Management of acute cancer treatment-induced diarrhea. Semin Oncol Nurs. 2003;19(4 Suppl 3):11-16. doi: 10.1053/j.soncn.2003.09.009. PMID: 14702928.
- 3. Khan HR, Ali Asghar S, Kanwal S, Qadar LT, Qadri KH. Diphenoxylate-atropine (Lomotil) Toxicity in Infantile Diarrhea: A Case Report of Therapeutic Failure. Cureus. 2019;9:11(10):e5875. doi: 10.7759/cureus.5875. PMID: 31763098; PMCID: PMC6834089.
- 4. Lustman F, Walters EG, Shroff NE, Akbar FA. Diphenoxylate hydrochloride (Lomotil) in the treatment of acute diarrhoea. Br J Clin Pract. 1987;41(3):648-651. PMID: 3318900.
- 5. McGuigan M, Lovejoy FH Jr. Overdose of Lomotil. Br Med J. 1978;1(6118):990. doi: 10.1136/bmj.1.6118.990-a. PMID: 638566; PMCID: PMC1603866.
Abstract
Diarrhea, which has infectious and non-infectious causes in etiology such as malabsorption, gastroenteritis, hypermotility, is a common symptom that can be seen in clinical situations managed by many medical disciplines. Diarrhea ranges from life-threatening clinical conditions to simple watery stools. Usually, treating the underlying disease and applying appropriate dietary interventions are sufficient to control diarrhea. However, when such measures are insufficient, a combination of loperamide or diphenoxylate atropine can be used to prolong transit time and increase fluid and electrolyte absorption.
Keywords
References
- 1. Awouters F, Niemegeers CJ, Janssen PA. Pharmacology of antidiarrheal drugs. Annu Rev Pharmacol Toxicol. 1983;23:279-301. doi: 10.1146/annurev.pa.23.040183.001431. PMID: 6307123.
- 2. Stern J, Ippoliti C. Management of acute cancer treatment-induced diarrhea. Semin Oncol Nurs. 2003;19(4 Suppl 3):11-16. doi: 10.1053/j.soncn.2003.09.009. PMID: 14702928.
- 3. Khan HR, Ali Asghar S, Kanwal S, Qadar LT, Qadri KH. Diphenoxylate-atropine (Lomotil) Toxicity in Infantile Diarrhea: A Case Report of Therapeutic Failure. Cureus. 2019;9:11(10):e5875. doi: 10.7759/cureus.5875. PMID: 31763098; PMCID: PMC6834089.
- 4. Lustman F, Walters EG, Shroff NE, Akbar FA. Diphenoxylate hydrochloride (Lomotil) in the treatment of acute diarrhoea. Br J Clin Pract. 1987;41(3):648-651. PMID: 3318900.
- 5. McGuigan M, Lovejoy FH Jr. Overdose of Lomotil. Br Med J. 1978;1(6118):990. doi: 10.1136/bmj.1.6118.990-a. PMID: 638566; PMCID: PMC1603866.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Letter to Editor |
| Authors | |
| Publication Date | April 30, 2023 |
| Submission Date | December 25, 2022 |
| Published in Issue | Year 2023 Volume: 15 Issue: 1 |
