BibTex RIS Cite

The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue

Year 2016, Volume: 3 Issue: 1, 47 - 50, 15.01.2016

Bekir Tasdemir Zeki Dostbil Ilhan Sezgin

Abstract

In this case report, we present a 36-year-old lactating woman, 10 months after delivery, who was referred to our clinic for a myocardial perfusion scintigraphy (MPS) due to chest pain. A scintigraphic procedure was performed according to the two-day protocol. On the first day, dipyridamole pharmacological stress Tc-99m MIBI MPS was performed, and on the second day, the same test was repeated while in a resting state without the administration of any pharmacological agent. The stress scan, compared to the rest scan, presented a higher uptake of Tc-99m MIBI in the breast tissue. The patient query revealed that the last breastfeeding was 12 hours before the stress scan and she did not breastfeed or express breast milk prior to the rest scan. Our findings suggest that ceasing the emptying of the mammary glands prior to the Tc-99m MIBI injection might be appropriate to decrease the radiation exposure of the mammary glands and the breast-fed baby.

Keywords

molecular imaging myocardial perfusion imaging SPECT Technetium Tc 99m Sestamibi

References

  • Okada RD, Glover D, Gaffney T, Williams S. MYOCARDIAL KINETICS OF TECHNETIUM-99M-HEXAKIS-2-METHOXY-2-METHYLPROPYL-ISONITRILE. Circulation. 1988;77(2):491-8.
  • Piwnicaworms D, Kronauge JF, Chiu ML. UPTAKE AND RETENTION OF HEXAKIS (2-METHOXYISOBUTYL ISONITRILE) TECHNETIUM(I) IN CULTURED CHICK MYOCARDIAL-CELLS - MITOCHONDRIAL AND PLASMA-MEMBRANE POTENTIAL DEPENDENCE. Circulation. 1990;82(5):1826-38.
  • Mattsson S, Johansson L, Leide-Svegborn S, Liniecki J, Nosske D, Riklund K, et al., editors. Current activities in the ICRP concerning estimation of radiation doses to patients from radiopharmaceuticals for diagnostic use. International Conference on Image Optimisation in Nuclear Medicine (OptiNM); 2011 2011
  • Mar 23-26; Cyprus2011.
  • Ramakrishna G, Miller TD. Significant breast uptake of Tc-99m sestamibi in an actively lactating woman during SPECT myocardial perfusion imaging. Journal of Nuclear Cardiology. 2004;11(2):222-3.
  • Rubow S, Klopper J, Wasserman H, Baard B, Vanniekerk M. THE EXCRETION OF RADIOPHARMACEUTICALS IN HUMAN BREAST-MILK - ADDITIONAL DATA AND DOSIMETRY. European Journal of Nuclear Medicine. 1994;21(2):144-53.
  • Spinka M, Illmann G, Algers B, Stetkova Z. The role of nursing frequency in milk production in domestic pigs. Journal of Animal Science. 1997;75(5):1223-8.
  • Mountford PJ, Coakley AJ. A REVIEW OF THE SECRETION OF RADIOACTIVITY IN HUMAN-BREAST MILK - DATA, QUANTITATIVE-ANALYSIS AND RECOMMENDATIONS. Nuclear Medicine Communications. 1989;10(1):15-27.
  • Hicks RJ, Binns D, Stabin MG. Pattern of uptake and excretion of F-18-FDG in the lactating breast. Journal of Nuclear Medicine. 2001;42(8):1238-42.
  • Yamamoto W, Shuke N, Usui K, Aburano T, Takehara N, Kikuchi K. Intense uptake of technetium-99m tetrofosmin by lactating breasts. Clinical Nuclear Medicine. 2001;26(1):76-7.

The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue

Year 2016, Volume: 3 Issue: 1, 47 - 50, 15.01.2016

Bekir Tasdemir Zeki Dostbil Ilhan Sezgin

Abstract

References

  • Okada RD, Glover D, Gaffney T, Williams S. MYOCARDIAL KINETICS OF TECHNETIUM-99M-HEXAKIS-2-METHOXY-2-METHYLPROPYL-ISONITRILE. Circulation. 1988;77(2):491-8.
  • Piwnicaworms D, Kronauge JF, Chiu ML. UPTAKE AND RETENTION OF HEXAKIS (2-METHOXYISOBUTYL ISONITRILE) TECHNETIUM(I) IN CULTURED CHICK MYOCARDIAL-CELLS - MITOCHONDRIAL AND PLASMA-MEMBRANE POTENTIAL DEPENDENCE. Circulation. 1990;82(5):1826-38.
  • Mattsson S, Johansson L, Leide-Svegborn S, Liniecki J, Nosske D, Riklund K, et al., editors. Current activities in the ICRP concerning estimation of radiation doses to patients from radiopharmaceuticals for diagnostic use. International Conference on Image Optimisation in Nuclear Medicine (OptiNM); 2011 2011
  • Mar 23-26; Cyprus2011.
  • Ramakrishna G, Miller TD. Significant breast uptake of Tc-99m sestamibi in an actively lactating woman during SPECT myocardial perfusion imaging. Journal of Nuclear Cardiology. 2004;11(2):222-3.
  • Rubow S, Klopper J, Wasserman H, Baard B, Vanniekerk M. THE EXCRETION OF RADIOPHARMACEUTICALS IN HUMAN BREAST-MILK - ADDITIONAL DATA AND DOSIMETRY. European Journal of Nuclear Medicine. 1994;21(2):144-53.
  • Spinka M, Illmann G, Algers B, Stetkova Z. The role of nursing frequency in milk production in domestic pigs. Journal of Animal Science. 1997;75(5):1223-8.
  • Mountford PJ, Coakley AJ. A REVIEW OF THE SECRETION OF RADIOACTIVITY IN HUMAN-BREAST MILK - DATA, QUANTITATIVE-ANALYSIS AND RECOMMENDATIONS. Nuclear Medicine Communications. 1989;10(1):15-27.
  • Hicks RJ, Binns D, Stabin MG. Pattern of uptake and excretion of F-18-FDG in the lactating breast. Journal of Nuclear Medicine. 2001;42(8):1238-42.
  • Yamamoto W, Shuke N, Usui K, Aburano T, Takehara N, Kikuchi K. Intense uptake of technetium-99m tetrofosmin by lactating breasts. Clinical Nuclear Medicine. 2001;26(1):76-7.
There are 10 citations in total.

Details

Primary Language English
Journal Section Case Reports
Authors

Bekir Tasdemir

Zeki Dostbil This is me

Ilhan Sezgin This is me

Publication Date January 15, 2016
Published in Issue Year 2016 Volume: 3 Issue: 1

Cite

APA Tasdemir, B., Dostbil, Z., & Sezgin, I. (2016). The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue. Medical Science and Discovery, 3(1), 47-50. https://doi.org/10.17546/msd.98350
AMA Tasdemir B, Dostbil Z, Sezgin I. The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue. Med Sci Discov. January 2016;3(1):47-50. doi:10.17546/msd.98350
Chicago Tasdemir, Bekir, Zeki Dostbil, and Ilhan Sezgin. “The Effect of the Time Interval Between the Last Breastfeeding and Tc-99m MIBI Injection on the Intensity of Tc-99m MIBI Uptake in Breast Tissue”. Medical Science and Discovery 3, no. 1 (January 2016): 47-50. https://doi.org/10.17546/msd.98350.
EndNote Tasdemir B, Dostbil Z, Sezgin I (January 1, 2016) The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue. Medical Science and Discovery 3 1 47–50.
IEEE B. Tasdemir, Z. Dostbil, and I. Sezgin, “The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue”, Med Sci Discov, vol. 3, no. 1, pp. 47–50, 2016, doi: 10.17546/msd.98350.
ISNAD Tasdemir, Bekir et al. “The Effect of the Time Interval Between the Last Breastfeeding and Tc-99m MIBI Injection on the Intensity of Tc-99m MIBI Uptake in Breast Tissue”. Medical Science and Discovery 3/1 (January 2016), 47-50. https://doi.org/10.17546/msd.98350.
JAMA Tasdemir B, Dostbil Z, Sezgin I. The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue. Med Sci Discov. 2016;3:47–50.
MLA Tasdemir, Bekir et al. “The Effect of the Time Interval Between the Last Breastfeeding and Tc-99m MIBI Injection on the Intensity of Tc-99m MIBI Uptake in Breast Tissue”. Medical Science and Discovery, vol. 3, no. 1, 2016, pp. 47-50, doi:10.17546/msd.98350.
Vancouver Tasdemir B, Dostbil Z, Sezgin I. The effect of the time interval between the last breastfeeding and Tc-99m MIBI injection on the intensity of Tc-99m MIBI uptake in breast tissue. Med Sci Discov. 2016;3(1):47-50.
 Download Cover Image