Abstract
References
- Ojo AO, Heinrichs D, Emond JC, Joshua J, McGowan, Mary K. Guidinger, et al. Organ donation and utilization in the USA. American Journal of Transplantation 2004; 4: 27-37.
- Dare AJ, Adam SB, John FF. "Critical care of the potential organ donor." Current neurology and neuroscience reports 2012; 12: 456-65.
- Çolakoğlu M, Nalbant M. "Transplantasyon için Denizli’den Kadavra Organ Çıkarımı: Deceased Organ Harvesting in Denizli." Official Journal of the Turkish Society of Nephrology 2005; 14: 3:123-126
- Tuncer M, Gürkan A, Yücetin L, Ersoy F, Demirbaş A, Akaydın M, et al. (2002, September). Evaluation of transplantation in one center: Akdeniz University model. In Transplantation proceedings 2002; 34: 2012.
- Kalayoğlu M. Starting a liver transplant program in Turkey; Akdeniz University model. Turk J Gastroenterol 2008; 19: 1.
- Wolfe RA, Ashby VB, Milford EL, Akinlolu O. Ojo, Robert E. Ettenger, et al. "Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first deceasedic transplant." New England Journal of Medicine 1999; 341: 1725-30.
- Yakupoğlu YK, Özden E, Koçak B. Three Years of Kidney Transplantation Experience at an University Hospital. Turkish Nephrology Dialysis and Transplantation Journal 2009; 18: 76-81.
- https://organ.saglik.gov.tr, Access date: 31 August 2020
- Murray JE, Merrill JP, Harrison JH, Carpenter, C. B. Renal homotransplantation in identical twins. J Am Soc Nephrol 2001; 12: 201-4.
- Merrill JP, Murray JE, Harrison JH, Guild WR. Successful homotransplantation of the human kidney between identical twins. Jama. 1984; 251: 2566-71.
- Suthanthıran, Manikkam; Strom, Terry B. Renal transplantation. New England Journal of Medicine, 1994, 331: 365-76.
- Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K. Comparison of survival probabilities for dialysis patients vs deceasedic renal transplant recipients. Jama 1993; 270: 1339-43.
- Ay N, Anıl M, Alp V, Sevuk U, Dinc B, Celik M. Evaluation of Quality of Life Early and Late After Kidney Transplantation. Annals of transplantation. 2015; 20: 493
- Ay N, Kaya Ş, Çiçek N, Bahadır MV. Böbrek Transplantasyonu Verilerimiz; Diyarbakır’da Tek Merkez Deneyimi. Dicle Tıp Dergisi. 2017; 1; 44(2):199-204.
- Krajewski W, Dembowski J, Kołodziej A, Malkiewicz B, Tupikowski K, Matuszewski M et al. Urological complications after renal transplantation–a single centre experience. Central European journal of urology. 2016; 69(3): 306.
- Liem YS, Weimar W. Early living-donor kidney transplantation: a review of the associated survival benefit. Transplantation. 2009; 15; 87(3): 317-18.
Abstract
Objective: Kidney transplantation is one of the most important treatments in end-stage renal disease (ESRD). We aimed to share our experiences in 60 (57 deceased donors, 3 living donors) kidney transplantation cases performed in our center between July 2017 and August 2020.
Material and methods: The demographic data of 60 patients with kidney transplantation performed in our kidney transplant center were evaluated in terms of causes and duration of renal failure human leucocyte antigen (HLA) tissue compatibility, immunosuppressive protocol used, antimicrobial agents, rejection status, graft loss, patient loss, postoperative surgical complications.
Results: 57 of our kidney transplants were made from deceased donors and 3 from living donors. The mean age of the patients was 44.66 (23-68) years. Kidney transplantation was performed in 8 patients (13.33%) in the preemptive period. The mean number of mismatches in kidney transplants was 3.95 (2-5) and the mean duration of renal replacement therapy (RRT) was 54.73 (0-270) months. While the mean follow-up period after transplantation was 18.86 (2-37) months, it was observed that the mean cold ischemia time was 742.8 (60-1080) minutes. Serum creatinine levels of 56 patients with functional grafts at the end of the first month 1.39 (0.5-4.9) mg/dL, 54 patients at the end of the sixth month, creatinine levels 1.29 (0.56-5.9) mg/dL, The creatinine levels of the 52 patients as of October 2020 were 1.37 (0.75-5.16) mg/dL. As surgical complications, hematoma developed in 5 patients (8.33%) and lymphocele in 3 patients (5%). Early graft loss developed in one patient with renal artery embolism and two patients with renal vein thrombosis, while chronic rejection developed in two patients. We performed a deceased kidney transplant again 14 months later in a patient who developed graft loss in the early period due to renal vein thrombosis. The kidney inserted later is functional in the 10th postoperative month. One of our patients died due to rhino-orbital mucor mycosis in the postoperative 2nd month, and one patient due to the development of sepsis due to infection in the hip prosthesis in the postoperative 6th month, while another patient died due to myocardial infarction in the postoperative 2nd month.
Conclusion: As a result, our kidney transplant center is in development. Our results obtained from 60 kidney transplants, almost all of which were performed from deceased donors, seem to be compatible with the literature. More detailed results can be obtained with the long-term follow-up results and the increase in the number of living donor transplants.
Keywords
References
- Ojo AO, Heinrichs D, Emond JC, Joshua J, McGowan, Mary K. Guidinger, et al. Organ donation and utilization in the USA. American Journal of Transplantation 2004; 4: 27-37.
- Dare AJ, Adam SB, John FF. "Critical care of the potential organ donor." Current neurology and neuroscience reports 2012; 12: 456-65.
- Çolakoğlu M, Nalbant M. "Transplantasyon için Denizli’den Kadavra Organ Çıkarımı: Deceased Organ Harvesting in Denizli." Official Journal of the Turkish Society of Nephrology 2005; 14: 3:123-126
- Tuncer M, Gürkan A, Yücetin L, Ersoy F, Demirbaş A, Akaydın M, et al. (2002, September). Evaluation of transplantation in one center: Akdeniz University model. In Transplantation proceedings 2002; 34: 2012.
- Kalayoğlu M. Starting a liver transplant program in Turkey; Akdeniz University model. Turk J Gastroenterol 2008; 19: 1.
- Wolfe RA, Ashby VB, Milford EL, Akinlolu O. Ojo, Robert E. Ettenger, et al. "Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first deceasedic transplant." New England Journal of Medicine 1999; 341: 1725-30.
- Yakupoğlu YK, Özden E, Koçak B. Three Years of Kidney Transplantation Experience at an University Hospital. Turkish Nephrology Dialysis and Transplantation Journal 2009; 18: 76-81.
- https://organ.saglik.gov.tr, Access date: 31 August 2020
- Murray JE, Merrill JP, Harrison JH, Carpenter, C. B. Renal homotransplantation in identical twins. J Am Soc Nephrol 2001; 12: 201-4.
- Merrill JP, Murray JE, Harrison JH, Guild WR. Successful homotransplantation of the human kidney between identical twins. Jama. 1984; 251: 2566-71.
- Suthanthıran, Manikkam; Strom, Terry B. Renal transplantation. New England Journal of Medicine, 1994, 331: 365-76.
- Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K. Comparison of survival probabilities for dialysis patients vs deceasedic renal transplant recipients. Jama 1993; 270: 1339-43.
- Ay N, Anıl M, Alp V, Sevuk U, Dinc B, Celik M. Evaluation of Quality of Life Early and Late After Kidney Transplantation. Annals of transplantation. 2015; 20: 493
- Ay N, Kaya Ş, Çiçek N, Bahadır MV. Böbrek Transplantasyonu Verilerimiz; Diyarbakır’da Tek Merkez Deneyimi. Dicle Tıp Dergisi. 2017; 1; 44(2):199-204.
- Krajewski W, Dembowski J, Kołodziej A, Malkiewicz B, Tupikowski K, Matuszewski M et al. Urological complications after renal transplantation–a single centre experience. Central European journal of urology. 2016; 69(3): 306.
- Liem YS, Weimar W. Early living-donor kidney transplantation: a review of the associated survival benefit. Transplantation. 2009; 15; 87(3): 317-18.
Details
| Primary Language | English |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | Original Articles |
| Authors | |
| Publication Date | October 29, 2020 |
| Submission Date | October 15, 2020 |
| Acceptance Date | October 24, 2020 |
| Published in Issue | Year 2020 Volume: 2 Issue: 4 |
