MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER

Yasin Durmuş; Derman Başaran; Alper Karalök; Günsu Kimyon Cömert; İsmet Çiğdem Kılıç; Osman Türkmen; Ahmet Taner Turan; Nurettin Boran

Case Report

PRİMER VAJİNAL KANSERDE VAJİNAL SU-BAZLI JEL YARDIMLI MANYETİK REZONANS GÖRÜNTÜLEME

Year 2016, Volume: 19 Issue: 3, 117 - 120, 21.05.2018

Yasin Durmuş Derman Başaran Alper Karalök Günsu Kimyon Cömert İsmet Çiğdem Kılıç Osman Türkmen Ahmet Taner Turan Nurettin Boran

Abstract

İki vajinal squamoz hücreli karsinom olgusunun, vajene su-bazlı jel doldurularak alınan manyetik rezonans görüntülemelerinin, genel
anestezi altında yapılan fizik muayene bulgularına yapabileceği ek katkıları değerlendirdik. Sunduğumuz iki olgu da genel anestezi altında
yapılan fizik muayeneye göre evre 1 olarak değerlendirildi. Ardından her iki hastaya da vajene su-bazlı jel ile doldurup vajen duvarlarının
kollapsını engelleyen, bu sayede vajendeki tümör anatomisini ve yayılımını daha iyi gösteren bir teknikle manyetik rezonans
görüntüleme(MRG) yapıldı. Olgulardan birinin MRG bulgularında subvajinal dokulara infiltrasyon izlendi. Bu nedenle bu hastada cerrahi
tedaviden vazgeçtik ve primer kemoradyasyon ile tedaviye karar verdik. Vajinal su-bazlı jel ile yapılan pelvik MRG’nin vajinal kanser
olgularında tümör anatomisini ve paravajinal dokulara infiltrasyonu göstermede genel anestezi altında yapılan fizik muayeneye üstün
olduğuna ve bu nadir jinelkolojik kanserlerin daha ideal yönetimine katkı sağlayacağına inanmaktayız.

Keywords

Vajinal kanser, Manyetik rezonans görüntüleme, Su-bazlı jel

References

1. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9
2. Daling JR, Madeleine MM, Schwartz SM, et al. A population-based study of squamous cell vaginal cancer: HPV and cofactors. Gynecol Oncol 2002;84:263e70.
3. Frank SJ, Deavers MT, Jhingran A, Bodurka DC, Eifel PJ. Primary adenocarcinoma of the vagina not associated with diethylstilbestrol (DES) exposure. Gynecol Oncol 2007;105:470
4. Lilic V, Lilic G, Filipovic S, Visnjic M, Zivadinovic R. Primary carcinoma of the vagina. J BUON 2010;15:241–7.
5. Hacker NF, Eifel PJ, van der Velden J. Cancer of the vagina. Int J Gynaecol Obstet 2012;119(Suppl. 2):S97–9.
6. Miner TJ, Delgado R, Zeisler J, et al. Primary vaginal melanoma: a critical analysis of therapy. Ann Surg Oncol 2004;11:34–9.
7. Kirschner AN, Kidd EA, Dewees T, Perkins SM. Treatment approach and outcomes of vaginal melanoma. Int J Gynecol Cancer 2013;23:1484–9.
8. Beller U, Benedet JL, Creasman WT, et al. Carcinoma of the vagina. FIGO 26th annual report on the results of treatment in gynecological cancer. Int J Gynaecol Obstet 2006;95(Suppl. 1):S29–42. 9. Hacker NF, Eifel PJ, van der Velden J. Cancer of the vagina. Int J Gynecol Obstet 2012;119(Suppl. 2):S97e9
10. Madsen BS, Jensen HL, van den Brule AJ, et al. Risk factors for invasive squamous cell carcinoma of the vulva and vaginaepopulation-based case-control study in Denmark. Int J Cancer 2008;122:2827e34.
11. Liao JB, Jean S, Wilkinson-Ryan I, et al. Vaginal intraepithelial neoplasia (VAIN) aft er radiation therapy for gynecologic malignancies: a clinically recalcitrant entity. Gynecol Oncol 2011;120(1):108e12.
12. Current FIGO staging for cancer of the vagina, fallopian tube, ovary, and gestational trophoblastic neoplasia. Int J Gynaecol Obstet 2009;105(1):3e4.
13. Rajaram S, Maheshwari A, Srivastava A Staging for vaginal cancer Best Practice & Research Clinical Obstetrics and Gynaecology 29 (2015) 822e832
14. Bipat S, Glas AS, van der Velden J, et al. Computed tomography and magnetic resonance imaging in staging of uterine cervical carcinoma: a systematic review. Gynecol Oncol 2003;91(1):59e66.
15. Hricak H, Gatsonis C, Chi DS, et al. Role of imaging in pretreatment evaluation of early invasive cervical cancer: results of the intergroup study American
16. Taylor MB, Dugar N, Davidson SE, et al. Magnetic resonance imaging of primary vaginal carcinoma. Clin Radiol 2007; 62(6):549e55.
17. Lee LJ, Jhingran A, Kidd E, et al. ACR appropriateness criteria® management of vaginal cancer. Oncology 2013 [accessed 28.10.14], http://www.cancernetwork. com/oncology-journal/acr-appropriateness-criteriamanagement-vaginal-cancer/accessed.
18. Griffi n N, Grant LA, Sala E. Magnetic resonance imaging of vaginal and vulval pathology. Eur Radiol 2008;18:1269e80
19. Chang YC, Hricak H, Th urnher S. Lacey CG vagina: evaluation with MR imaging. Part II. Neoplasms. Radiology 1988;169: 175e9.
20. Young P, Daniel B, Sommer G, Kim B, Herfk ens R Intravaginal Gel for Staging of Female Pelvic Cancers Preliminary Report of Safety, Distention, and Gel-Mucosal Contrast During Magnetic Resonance Examination. Comput Assist Tomogr & Volume 36, Number 2, March/ April 2012
21. Atcı N, Özgür T, Öztürk F, Dolapçıoğlu KS Utility of intravaginal ultrasound gel for local staging of cervical carcinoma on MRI. Clinical Imaging 40 (2016) 1104- 1107

MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER

Year 2016, Volume: 19 Issue: 3, 117 - 120, 21.05.2018

Yasin Durmuş Derman Başaran Alper Karalök Günsu Kimyon Cömert İsmet Çiğdem Kılıç Osman Türkmen Ahmet Taner Turan Nurettin Boran

Abstract

We report two cases of vaginal squamoz cell carcinoma with magnetic resonance imaging findings. Both of the patients were staged as
stage 1 with physical examination findings under general anesthesia. We performed magnetic resonance imaging for these patients filling
water-based gel to their vagina during the scan for preventing collapse of vaginal walls so that we could reveal the tumor anatomy and
extension more accurately. One of the patients MRI findings showed an infiltration through subvaginal tissues. So we abandoned surgical
treatment for this patient and choose radiotherapy. We think that, pelvic MRI performed with vaginal water-based gel can demonstrate
tumor infiltration to paravaginal tissues better than physical examination, which helps well-directed management of this rare gynecological
cancer

Keywords

Vaginal cancer, Magnetic resonance imaging, Water-based gel

References

1. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9
2. Daling JR, Madeleine MM, Schwartz SM, et al. A population-based study of squamous cell vaginal cancer: HPV and cofactors. Gynecol Oncol 2002;84:263e70.
3. Frank SJ, Deavers MT, Jhingran A, Bodurka DC, Eifel PJ. Primary adenocarcinoma of the vagina not associated with diethylstilbestrol (DES) exposure. Gynecol Oncol 2007;105:470
4. Lilic V, Lilic G, Filipovic S, Visnjic M, Zivadinovic R. Primary carcinoma of the vagina. J BUON 2010;15:241–7.
5. Hacker NF, Eifel PJ, van der Velden J. Cancer of the vagina. Int J Gynaecol Obstet 2012;119(Suppl. 2):S97–9.
6. Miner TJ, Delgado R, Zeisler J, et al. Primary vaginal melanoma: a critical analysis of therapy. Ann Surg Oncol 2004;11:34–9.
7. Kirschner AN, Kidd EA, Dewees T, Perkins SM. Treatment approach and outcomes of vaginal melanoma. Int J Gynecol Cancer 2013;23:1484–9.
8. Beller U, Benedet JL, Creasman WT, et al. Carcinoma of the vagina. FIGO 26th annual report on the results of treatment in gynecological cancer. Int J Gynaecol Obstet 2006;95(Suppl. 1):S29–42. 9. Hacker NF, Eifel PJ, van der Velden J. Cancer of the vagina. Int J Gynecol Obstet 2012;119(Suppl. 2):S97e9
10. Madsen BS, Jensen HL, van den Brule AJ, et al. Risk factors for invasive squamous cell carcinoma of the vulva and vaginaepopulation-based case-control study in Denmark. Int J Cancer 2008;122:2827e34.
11. Liao JB, Jean S, Wilkinson-Ryan I, et al. Vaginal intraepithelial neoplasia (VAIN) aft er radiation therapy for gynecologic malignancies: a clinically recalcitrant entity. Gynecol Oncol 2011;120(1):108e12.
12. Current FIGO staging for cancer of the vagina, fallopian tube, ovary, and gestational trophoblastic neoplasia. Int J Gynaecol Obstet 2009;105(1):3e4.
13. Rajaram S, Maheshwari A, Srivastava A Staging for vaginal cancer Best Practice & Research Clinical Obstetrics and Gynaecology 29 (2015) 822e832
14. Bipat S, Glas AS, van der Velden J, et al. Computed tomography and magnetic resonance imaging in staging of uterine cervical carcinoma: a systematic review. Gynecol Oncol 2003;91(1):59e66.
15. Hricak H, Gatsonis C, Chi DS, et al. Role of imaging in pretreatment evaluation of early invasive cervical cancer: results of the intergroup study American
16. Taylor MB, Dugar N, Davidson SE, et al. Magnetic resonance imaging of primary vaginal carcinoma. Clin Radiol 2007; 62(6):549e55.
17. Lee LJ, Jhingran A, Kidd E, et al. ACR appropriateness criteria® management of vaginal cancer. Oncology 2013 [accessed 28.10.14], http://www.cancernetwork. com/oncology-journal/acr-appropriateness-criteriamanagement-vaginal-cancer/accessed.
18. Griffi n N, Grant LA, Sala E. Magnetic resonance imaging of vaginal and vulval pathology. Eur Radiol 2008;18:1269e80
19. Chang YC, Hricak H, Th urnher S. Lacey CG vagina: evaluation with MR imaging. Part II. Neoplasms. Radiology 1988;169: 175e9.
20. Young P, Daniel B, Sommer G, Kim B, Herfk ens R Intravaginal Gel for Staging of Female Pelvic Cancers Preliminary Report of Safety, Distention, and Gel-Mucosal Contrast During Magnetic Resonance Examination. Comput Assist Tomogr & Volume 36, Number 2, March/ April 2012
21. Atcı N, Özgür T, Öztürk F, Dolapçıoğlu KS Utility of intravaginal ultrasound gel for local staging of cervical carcinoma on MRI. Clinical Imaging 40 (2016) 1104- 1107

There are 20 citations in total.

Details

Primary Language	English
Journal Section	Case Report
Authors	Yasin Durmuş This is me Derman Başaran Alper Karalök This is me Günsu Kimyon Cömert This is me İsmet Çiğdem Kılıç This is me Osman Türkmen This is me Ahmet Taner Turan This is me Nurettin Boran This is me
Publication Date	May 21, 2018
Submission Date	January 10, 2017
Published in Issue	Year 2016 Volume: 19 Issue: 3

Cite

APA	Durmuş, Y., Başaran, D., Karalök, A., Cömert, G. K., et al. (2018). MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER. Türk Jinekolojik Onkoloji Dergisi, 19(3), 117-120.
AMA	Durmuş Y, Başaran D, Karalök A, Cömert GK, Kılıç İÇ, Türkmen O, Turan AT, Boran N. MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER. TRSGO Dergisi. May 2018;19(3):117-120.
Chicago	Durmuş, Yasin, Derman Başaran, Alper Karalök, Günsu Kimyon Cömert, İsmet Çiğdem Kılıç, Osman Türkmen, Ahmet Taner Turan, and Nurettin Boran. “MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER”. Türk Jinekolojik Onkoloji Dergisi 19, no. 3 (May 2018): 117-20.
EndNote	Durmuş Y, Başaran D, Karalök A, Cömert GK, Kılıç İÇ, Türkmen O, Turan AT, Boran N (May 1, 2018) MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER. Türk Jinekolojik Onkoloji Dergisi 19 3 117–120.
IEEE	Y. Durmuş, “MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER”, TRSGO Dergisi, vol. 19, no. 3, pp. 117–120, 2018.
ISNAD	Durmuş, Yasin et al. “MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER”. Türk Jinekolojik Onkoloji Dergisi 19/3 (May 2018), 117-120.
JAMA	Durmuş Y, Başaran D, Karalök A, Cömert GK, Kılıç İÇ, Türkmen O, Turan AT, Boran N. MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER. TRSGO Dergisi. 2018;19:117–120.
MLA	Durmuş, Yasin et al. “MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER”. Türk Jinekolojik Onkoloji Dergisi, vol. 19, no. 3, 2018, pp. 117-20.
Vancouver	Durmuş Y, Başaran D, Karalök A, Cömert GK, Kılıç İÇ, Türkmen O, Turan AT, Boran N. MAGNETIC RESONANCE IMAGING GUIDES THE MANAGEMENT OF PRIMARY VAGINAL CANCER. TRSGO Dergisi. 2018;19(3):117-20.