Aims: The current study aimed to examine the values of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) in generalized anxiety disorder (GAD).
Methods: In this retrospective study, 147 GAD patients who did not receive treatment and 154 healthy controls with similar characteristics to the patient group were included. NLR, PLR, MLR, SII, and SIRI values calculated from the complete blood count values of the GAD group were compared with age- and sex-matched healthy controls.
Results: Neutrophil, lymphocyte, monocyte, platelet counts and NLR, MLR, SII, and SIRI values were significantly higher in the GAD group compared to healthy controls (p<0.001, p=0.001, p<0.001, p<0.001, p<0.001, p=0.003, p<0.001, p<0.001, respectively). The logistic regression analysis revealed that SII and SIRI were identified as significant variables associated with receiving a diagnosis of GAD.
Conclusion: Inflammatory markers such as NLR, MLR, SII, and SIRI are thought to play an important role in the evaluation of inflammatory activity in GAD. However, larger and more comprehensive studies are needed.
Generalized anxiety disorder inflammatory biomarker systemic immune-inflammation index systemic inflammatory response index
Birincil Dil | İngilizce |
---|---|
Konular | Psikiyatri |
Bölüm | Research Articles |
Yazarlar | |
Yayımlanma Tarihi | 8 Mart 2024 |
Gönderilme Tarihi | 29 Ocak 2024 |
Kabul Tarihi | 18 Şubat 2024 |
Yayımlandığı Sayı | Yıl 2024 Cilt: 6 Sayı: 2 |
Üniversitelerarası Kurul (ÜAK) Eşdeğerliği: Ulakbim TR Dizin'de olan dergilerde yayımlanan makale [10 PUAN] ve 1a, b, c hariç uluslararası indekslerde (1d) olan dergilerde yayımlanan makale [5 PUAN]
- Dahil olduğumuz İndeksler (Dizinler) ve Platformlar sayfanın en altındadır.
Not: Dergimiz WOS indeksli değildir ve bu nedenle Q olarak sınıflandırılmamaktadır.
Yüksek Öğretim Kurumu (YÖK) kriterlerine göre yağmacı/şüpheli dergiler hakkındaki kararları ile yazar aydınlatma metni ve dergi ücretlendirme politikasını tarayıcınızdan indirebilirsiniz. https://dergipark.org.tr/tr/journal/3449/page/10809/update
Dergi Dizin ve Platformları
TR Dizin ULAKBİM, Google Scholar, Crossref, Worldcat (OCLC), DRJI, EuroPub, OpenAIRE, Turkiye Citation Index, Turk Medline, ROAD, ICI World of Journal's, Index Copernicus, ASOS Index, General Impact Factor, Scilit.