Geri Çekildi: Gebeliğin ilk üç ayında teşhis edilen COVID-19 hastalığının obstetrik sonuçlara etkisi
Geri Çekme Notu
'The effect of COVID-19 disease diagnosed in the first trimester of pregnancy on obstetric outcomes' isimli, JGON 19-3 sayıda yayınlanan makale sorumlu yazarın isteği üzerine geri çekilmiştir.
Öz
Amaç: Bu makalenin amacı, ilk trimesterde koronavirüs 2019 hastalığı tanısı alan gebeliklerin maternal, fetal ve obstetrik sonuçlarını analiz etmektir.
Yöntemler: Gebeliğin ilk üç ayında COVID-19 tanısı konan ve hastaneye yatırılan hastaların prospektif analizi yapıldı. Gebeliğin sonraki haftalarında obstetrik komplikasyonlar, doğum ve neonatal sonuçlar rapor edildi.
Bulgular: Yetmiş beş hastayı çalışmaya dahil ettik. Kovid-19 pozitif olan gebelerin ortalama yaşı 28.2 yıl, ortalama gebelik haftası 9.9 hafta idi. Ortalama doğum haftası 31,65±9,47 idi. Hastaların 27'si erken doğum yaptı. Hiçbir bebekte tüm olgular arasında neonatal Sars Cov-2 pozitifliği yoktu. Şiddetli Covid-19 hastası olan 29 hastanın 15'i erken doğumla sonuçlandı.
Sonuç: İlk trimesterinde ağır Covid-19 olan hamile kadınlar, erken doğum, intrauterin fetal ölüm ve perinatal komplikasyon açısından daha yüksek risk altındadır.
Anahtar Kelimeler
covid-19 sars cov-2 ve gebelik ilk trimestırda coronavirus-2019 erken doğum
Kaynakça
- 1. WHO. Coronavirus disease 2019 (COVID-19) Situation Report – 52 [Internet]. p. 1–9. Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200312-sitrep-52-covid-19.pdf
- 2. Zhang Y-Z. Novel 2019 coronavirus genome. Virological org. 2020; 3. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. New England journal of medicine. 2020; 4. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The lancet. 2020;395(10224):565–74.
- 5. Hui DSC, Zumla A. Severe acute respiratory syndrome: historical, epidemiologic, and clinical features. Infectious Disease Clinics. 2019;33(4):869–89.
- 6. Rasmussen S, Smulian J, Lednicky J, Wen T, Jamieson DJ. Enfermedad por coronavirus 2019 (COVID–19) y embarazo: lo que los obstetras deben saber. Reseñas de Expertos. 2020;222(5):426–501.
- 7. Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. American journal of obstetrics and gynecology. 2020;223(1):111-e1.
- 8. McIntosh K, Hirsch MS, Bloom A. Coronavirus disease 2019 (COVID-19). UpToDate Hirsch MS Bloom. 2020;5(1). 9. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet. 2020;395(10223):497–506.
- 10. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. New England journal of medicine. 2020;382(18):1708–20.
- 11. Xu H, Huang S, Liu S, Deng J, Jiao B, Ai L, et al. Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O. Available at SSRN 3548746. 2020;
- 12. Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RT-PCR test results in patients recovered from COVID-19. Jama. 2020;323(15):1502–3.
- 13. Of NI, Health. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines [Internet]. Available from: https://files.covid19treatmentguidelines.nih.gov/guidelines/covid19treatmentguidelines.pdf
- 14. Khalil A, Kalafat E, Benlioglu C, O’Brien P, Morris E, Draycott T, et al. SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes. EClinicalMedicine. 2020;25:100446.
- 15. Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID‐19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound in Obstetrics & Gynecology. 2020;56(1):15–27.
- 16. WHO COVID-19 Case definition [Internet]. Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-Surveillance_Case_Definition-2020.2
- 17. Azap Ö. 5. COVID-19’da hastalık ağırlık tanımları ve yatış kriterleri. COVID-19 Görev Grubu Görüş Raporu. :30.
- 18. Rosen H, Bart Y, Zlatkin R, Ben-Sira L, Ben Bashat D, Amit S, et al. Fetal and Perinatal Outcome Following First and Second Trimester COVID-19 Infection: Evidence from a Prospective Cohort Study. Vol. 10, Journal of Clinical Medicine . 2021.
- 19. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2021 Feb;57(2):232–41.
- 20. Cosma S, Carosso AR, Cusato J, Borella F, Carosso M, Bovetti M, et al. Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients. American journal of obstetrics and gynecology. 2021 Apr;224(4):391.e1-391.e7.
- 21. la Cour Freiesleben N, Egerup P, Hviid KVR, Severinsen ER, Kolte AM, Westergaard D, et al. SARS-CoV-2 in first trimester pregnancy: a cohort study. Human reproduction (Oxford, England). 2021 Jan;36(1):40–7.
- 22. Zeng L, Xia S, Yuan W, Yan K, Xiao F, Shao J, et al. Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China. JAMA Pediatrics [Internet]. 2020;174(7):722–5. Available from: https://doi.org/10.1001/jamapediatrics.2020.0878
- 23. Di Mascio D, Sen C, Saccone G, Galindo A, Grünebaum A, Yoshimatsu J, et al. Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19. Journal of perinatal medicine. 2020;48(9):950–8.
Geri Çekildi: The effect of COVID-19 disease diagnosed in the first trimester of pregnancy on obstetric outcomes
Geri Çekme Notu
Öz
Aim: The purpose of this article is to analyze the maternal, fetal, and obstetric outcomes of pregnancies diagnosed with coronavirus 2019 disease in the first trimester.
Methods: A prospective analysis of patients diagnosed with COVID-19 during the first trimester of pregnancy and hospitalized was performed. Obstetric complications, delivery, and neonatal outcomes were reported in the following weeks of pregnancy.
Results: We included seventy-five patients in the study. The mean age of pregnant women, Covid-19 positive, was 28.2 years, and the mean gestational week was 9.9 weeks. The mean delivery week was 31.65±9.47. Twenty-seven of the patients had preterm delivery. There was no neonatal Sars Cov-2 positivity among all the cases in any babies. Fifteen of twenty-nine patients with severe Covid-19 resulted in preterm delivery.
Conclusion: Pregnant women with severe Covid-19 in their first trimester are at higher risk of premature birth, intrauterine fetal death, and perinatal complications
Anahtar Kelimeler
covid-19 sars cov-2 and pregnancy coronavirus 2019 in the first trimestr preterm birth
Kaynakça
- 1. WHO. Coronavirus disease 2019 (COVID-19) Situation Report – 52 [Internet]. p. 1–9. Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200312-sitrep-52-covid-19.pdf
- 2. Zhang Y-Z. Novel 2019 coronavirus genome. Virological org. 2020; 3. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. New England journal of medicine. 2020; 4. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The lancet. 2020;395(10224):565–74.
- 5. Hui DSC, Zumla A. Severe acute respiratory syndrome: historical, epidemiologic, and clinical features. Infectious Disease Clinics. 2019;33(4):869–89.
- 6. Rasmussen S, Smulian J, Lednicky J, Wen T, Jamieson DJ. Enfermedad por coronavirus 2019 (COVID–19) y embarazo: lo que los obstetras deben saber. Reseñas de Expertos. 2020;222(5):426–501.
- 7. Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. American journal of obstetrics and gynecology. 2020;223(1):111-e1.
- 8. McIntosh K, Hirsch MS, Bloom A. Coronavirus disease 2019 (COVID-19). UpToDate Hirsch MS Bloom. 2020;5(1). 9. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet. 2020;395(10223):497–506.
- 10. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. New England journal of medicine. 2020;382(18):1708–20.
- 11. Xu H, Huang S, Liu S, Deng J, Jiao B, Ai L, et al. Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O. Available at SSRN 3548746. 2020;
- 12. Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RT-PCR test results in patients recovered from COVID-19. Jama. 2020;323(15):1502–3.
- 13. Of NI, Health. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines [Internet]. Available from: https://files.covid19treatmentguidelines.nih.gov/guidelines/covid19treatmentguidelines.pdf
- 14. Khalil A, Kalafat E, Benlioglu C, O’Brien P, Morris E, Draycott T, et al. SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes. EClinicalMedicine. 2020;25:100446.
- 15. Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID‐19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound in Obstetrics & Gynecology. 2020;56(1):15–27.
- 16. WHO COVID-19 Case definition [Internet]. Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-Surveillance_Case_Definition-2020.2
- 17. Azap Ö. 5. COVID-19’da hastalık ağırlık tanımları ve yatış kriterleri. COVID-19 Görev Grubu Görüş Raporu. :30.
- 18. Rosen H, Bart Y, Zlatkin R, Ben-Sira L, Ben Bashat D, Amit S, et al. Fetal and Perinatal Outcome Following First and Second Trimester COVID-19 Infection: Evidence from a Prospective Cohort Study. Vol. 10, Journal of Clinical Medicine . 2021.
- 19. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2021 Feb;57(2):232–41.
- 20. Cosma S, Carosso AR, Cusato J, Borella F, Carosso M, Bovetti M, et al. Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients. American journal of obstetrics and gynecology. 2021 Apr;224(4):391.e1-391.e7.
- 21. la Cour Freiesleben N, Egerup P, Hviid KVR, Severinsen ER, Kolte AM, Westergaard D, et al. SARS-CoV-2 in first trimester pregnancy: a cohort study. Human reproduction (Oxford, England). 2021 Jan;36(1):40–7.
- 22. Zeng L, Xia S, Yuan W, Yan K, Xiao F, Shao J, et al. Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China. JAMA Pediatrics [Internet]. 2020;174(7):722–5. Available from: https://doi.org/10.1001/jamapediatrics.2020.0878
- 23. Di Mascio D, Sen C, Saccone G, Galindo A, Grünebaum A, Yoshimatsu J, et al. Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19. Journal of perinatal medicine. 2020;48(9):950–8.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Kadın Hastalıkları ve Doğum |
| Bölüm | Araştırma Makaleleri |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2022 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 19 Sayı: 4 |
