Objective: The
aim of this study was to investigate the survival data of patients with acute
myeloid leukemia (AML) and to determine the risk factors that can be easily evaluated.
Method: A
retrospective analysis was made of the AML patients admitted to our center between
2009-2018. Demographic data and disease data were analyzed and response rates,
overall survival (OS) and progression-free survival (PFS) rates were
calculated. Factors affecting survival were determined using Cox-regression
analysis.
Results: A
total of 119 patients were included in the study during the 9-year study
period. Of these, 21 patients had secondary AML and 11 had acute promyelocytic
leukemia (APL). The mean follow-up period was 12.43 ± 15.63 months. OS of all
patients was 9.20 months and PFS was 7.23 months. Age and leukocyte count at
the time of diagnosis were found to have a significant impact on both OS and
PFS (p <0.05).
Conclusion:
In addition to genetic and molecular features, which are expensive and not
easily available, the age and leukocyte count of AML patients remain important as
prognostic factors.
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 2 Mart 2020 |
Kabul Tarihi | 15 Ocak 2020 |
Yayımlandığı Sayı | Yıl 2020 Cilt: 12 Sayı: 1 |