Öz
Henoch Schönlein Purpurası artrit, karın ağrısı, non-trombositopenik purpura ve böbrek tutulumu ile seyreden, çocukluk çağında en sık görülen küçük damar vaskülitidir. Palpabl purpura genelde hastalığın ilk bulgusu olarak ortaya çıkar. Ancak gastrointestinal semptomlar nadiren döküntüden önce ortaya çıkarak tanıda gecikmelere neden olabilmektedir. Bu yazıda akut batın kliniğiyle acil servisimize başvuran, apendektomi yapılan ve klinik takibi sırasında cilt tutulumunun ortaya çıkması ile Henoch Schönlein Purpurası tanısı alan bir vaka sunuyoruz. Vakamızın önemli olan bir diğer noktası da; Henoch Schönlein Purpura atağı sonrasında tekrarlayan karın ağrısı anamnezi olması üzerine yapılan genetik analiz ile hastaya Ailevi Akdeniz Ateşi tanısı konmasıdır.
Anahtar Kelimeler
Henoch Schönlein Purpurası , karın ağrısı non-trombositopenik purpura Ailevi Akdeniz Ateşi
Destekleyen Kurum
Yok.
Proje Numarası
yok
Kaynakça
- 1. Bayram C, Demircin G, et al. Prevalence of MEFV gene mutations and their clinical correlations in Turkish children with Henoch-Schönlein purpura. Acta Paediatr. 2011;100(5):745.
- 2. Bagga A, Dillon MJ. Leukocytoclastic vasculitis. In: Cassidy JT, Petty RE (eds). Textbook of Pediatric Rheumatology WB Saunders Company. Philadelphia, 2001 ve 569-79.
- 3. Szer IS. Henoch-Schönlein purpura. Curr Opin Rheumatol 1994;6:25-31.
- 4. Chang WL, Yang YH, et al. Gastrointestinal manifestations in Henoch-Schönlein purpura: a review of 261 patients. Acta Paediatr 2004 and 93:1427.
- 5. Rozenbaum M, Rosner I. The clinicak features of FMF of elderly onset. Clin Exp Rheumatol 1984, 12:347-48.
- 6. Feldth RH, Stickler GB. The gastrointestinal manifestations of anaphylactoid purpura in children. Proc Staff Meet Mayo Clin. 1962;37:465.
- 7. Ghrahani R, Ledika MA, et al. Age of onset as a risk factor of renal involvement in Henoch-Schönlein purpura. Asia Pac Allergy. 2014 Jan;4(1):42-7.
- 8. Ardoin SP, Fels E. Vasculitis Syndromes. In: Kliegman RM, Stanton BF, Schor NF, St.Geme III JW, Behrman RE (eds). Nelson Textbook of Pediatrıcs, 19th ed. Philadelphia, Elsevier Saunders, 2011: 867-71.
- 9. Weiss PF, Feinstein JA, et al. Effects of corticosteroid on Henoch-Schönlein purpura: a systematic review. Pediatrics 2007;120(5):1079.
- 10. Acar B, Arıkan Y, et al. System involvement evaluation of 168 case which is observed with henoch schönlein vasculitis in childhood. Ege Journal of Medicine 49 (1): 7-12, 2010.
- 11. Piram M, Mahr A. Epidemiology of immunoglobulin A vasculitis (Henoch-Schönlein): current state of knowledge. Curr Opin Rheumatol. 2013 Mar;25(2):171-8.
- 12. Ozen S, Pistorio A, et al. EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis. 2010;69(5):798.
- 13. Gunasekaran TS, Berman J, et al. Duodenojejunitis: is it idiopathic or is it Henoch-Schönlein purpura without the purpura? J Pediatr Gastroenterol Nutr. 2000;30(1):22.
Familial Mediterranean Fever Present with Gastrointestinal Manifestations of Henoch Schonlein Purpura
Öz
Henoch Schönlein Purpura is the most common small vessel vasculitis in childhood which is characterized with non-thrombocytopenic purpuric skin rash, arthritis, abdominal pain and renal disease. Palpable purpura usually occurs as the first clinical finding. However, gastrointestinal symptoms can rarely appear before the rash and may cause delays in diagnosis. Here, we present a case of Henoch Schönlein Purpura who underwent appendectomy with the diagnosis of acute abdomen and developed skin involvement in clinical follow-up. Another significant point of the case is having anamnesis of recurrent abdominal pain and the diagnosis of Familial Mediterranean Fever by genetic analysis after Henoch Schönlein Purpura attack.
Anahtar Kelimeler
Henoch Schonlein Purpura abdominal pain nonthrombocytopenic purpura Familial Mediterranean Fever
Proje Numarası
yok
Kaynakça
- 1. Bayram C, Demircin G, et al. Prevalence of MEFV gene mutations and their clinical correlations in Turkish children with Henoch-Schönlein purpura. Acta Paediatr. 2011;100(5):745.
- 2. Bagga A, Dillon MJ. Leukocytoclastic vasculitis. In: Cassidy JT, Petty RE (eds). Textbook of Pediatric Rheumatology WB Saunders Company. Philadelphia, 2001 ve 569-79.
- 3. Szer IS. Henoch-Schönlein purpura. Curr Opin Rheumatol 1994;6:25-31.
- 4. Chang WL, Yang YH, et al. Gastrointestinal manifestations in Henoch-Schönlein purpura: a review of 261 patients. Acta Paediatr 2004 and 93:1427.
- 5. Rozenbaum M, Rosner I. The clinicak features of FMF of elderly onset. Clin Exp Rheumatol 1984, 12:347-48.
- 6. Feldth RH, Stickler GB. The gastrointestinal manifestations of anaphylactoid purpura in children. Proc Staff Meet Mayo Clin. 1962;37:465.
- 7. Ghrahani R, Ledika MA, et al. Age of onset as a risk factor of renal involvement in Henoch-Schönlein purpura. Asia Pac Allergy. 2014 Jan;4(1):42-7.
- 8. Ardoin SP, Fels E. Vasculitis Syndromes. In: Kliegman RM, Stanton BF, Schor NF, St.Geme III JW, Behrman RE (eds). Nelson Textbook of Pediatrıcs, 19th ed. Philadelphia, Elsevier Saunders, 2011: 867-71.
- 9. Weiss PF, Feinstein JA, et al. Effects of corticosteroid on Henoch-Schönlein purpura: a systematic review. Pediatrics 2007;120(5):1079.
- 10. Acar B, Arıkan Y, et al. System involvement evaluation of 168 case which is observed with henoch schönlein vasculitis in childhood. Ege Journal of Medicine 49 (1): 7-12, 2010.
- 11. Piram M, Mahr A. Epidemiology of immunoglobulin A vasculitis (Henoch-Schönlein): current state of knowledge. Curr Opin Rheumatol. 2013 Mar;25(2):171-8.
- 12. Ozen S, Pistorio A, et al. EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis. 2010;69(5):798.
- 13. Gunasekaran TS, Berman J, et al. Duodenojejunitis: is it idiopathic or is it Henoch-Schönlein purpura without the purpura? J Pediatr Gastroenterol Nutr. 2000;30(1):22.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Proje Numarası | yok |
| Yayımlanma Tarihi | 29 Mayıs 2021 |
| Kabul Tarihi | 14 Mayıs 2021 |
| Yayımlandığı Sayı | Yıl 2021 Cilt: 5 Sayı: 2 |
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