SCUBE-1 is a newly identified, secreted cell surface protein that is determined during early embryogenesis. This protein consists of cascading EGF-like repeats following the N-terminal signal peptide sequence, a spacer region, cysteine-rich repeat motifs, and a CUB domain at the C-terminus. These molecules are stored in alpha granules in inactivated platelets, translocated to the platelet surface after activation by thrombin, secreted as small soluble fragments, and incorporated into the thrombus.
Birincil Dil | İngilizce |
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Konular | Sağlık Kurumları Yönetimi |
Bölüm | Letter to Editor |
Yazarlar | |
Erken Görünüm Tarihi | 18 Mart 2023 |
Yayımlanma Tarihi | 18 Mart 2023 |
Gönderilme Tarihi | 7 Aralık 2022 |
Kabul Tarihi | 26 Ocak 2023 |
Yayımlandığı Sayı | Yıl 2023 Cilt: 40 Sayı: 1 |
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