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An Unusual Presentation of Multiple Myeloma: Plasmacytic Ascites Complicated by Duodenal Involvement Multiple Myeloma’nın Nadir bir Prezentasyonu: Duedonal Tutulum ile Komplike olan Plazmasitik Asit

Yıl 2017, Cilt: 39 Sayı: 2, 60 - 64, 21.07.2017
https://doi.org/10.20515/otd.308424

Öz

Abstract: The incidence of gastrointestinal system involvement during the course
of multiple myeloma (MM) is rare.
The usually
affected sites of GI tract are small and large bowel, stomach, and rarely
esophagus. Only a few MM cases are also known with myelomatous ascites at
presentation. In this report, we present a 67-year old patient who developed
myelomatosus ascites. Although rare, MM can involve extramedullary areas such
as duodenum and different kinds of complications may occur. In addition to
standard diagnostic and treatment methods, individualized diagnostic and
therapeutic options should be considered for such patients.



Key words: multiple myeloma, ascites, duodenal involvement


Öz: Multiple myeloma (MM) seyrinde gastrointestinal sistem tutulumu
nadirdir. Gastrointestinal sistemde sıklıkla ince ve kalın bağırsak, mide ve
nadiren de özefagus tutulur. MM vakalarında myeloma bağlı asit ile başvuran
hasta sayısı çok azdır. Bu vaka sunumunda myeloma bağlı asit gelişen 67 yaşında
bir erkek hasta sunulmuştur. Nadir görülmesine rağmen MM duodenum gibi
extramedüller bölgeleri tutabilir ve buna bağlı farklı komplikasyonlar gelişebilir.
Bu tür hastalarda standart tanı ve tedavi yöntemlerine ek olarak,
bireyselleştirilmiş tanı ve tedavi seçenekleri de düşünülmelidir.

Anahtar Kelimeler: multiple myelom,
asit, duodenal tutulum

Kaynakça

  • 1.Alexiou C, Reinhardt JK, Dietzfelbinger H, et al. Extramedullary plasmacytoma: tumor occurrence andtherap eutic concepts. Cancer 1999;85:2305–14.
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  • 9.Attwell A, Dee E, Russ P, Nash R, Shah R. Multiple myeloma involving the porta hepatis and peritoneum causing biliary obstruction and malignant ascites. Dig Dis Sci. 2005 Jun;50(6):1068-71
  • 10.Hayes D, BennettW: Extramedullary lesions in multiple myeloma: review of literature and pathologic studies. Arch Pathol Lab Med 53:317–329, 1952
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  • 13.Kodama Y et al. (1999) MALT lymphoma simulating an extramedullary plasmacytoma of the stomach. Am J Med 107: 530–532
  • 14.Tada S et al. (1990) Endoscopic and biopsy findings of the upper digestive tract in patients with amyloidosis. Gastrointest Endosc 36: 10–14
  • 15.Hainsworth JD et al. (1991) Poorly differentiated carcinoma of unknown primary site: clinical usefulness of immunoperoxidase staining. J Clin Oncol 9:1931–1938
  • 16.Esfandyari T, Abraham SC, Arora AS. Gastrointestinal plasmacytoma that caused anemia in a patient with multiple myeloma. Nat Clin Pract Gastroenterol Hepatol. 2007 Feb;4(2):111-5.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Konular Sağlık Kurumları Yönetimi
Bölüm OLGU SUNUMLARI / CASE REPORTS
Yazarlar

Güven Barış Cansu Bu kişi benim

Havva Üsküdar Teke

Olga Meltam Akay Bu kişi benim

Emre Entok Bu kişi benim

Yayımlanma Tarihi 21 Temmuz 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 39 Sayı: 2

Kaynak Göster

Vancouver Cansu GB, Üsküdar Teke H, Akay OM, Entok E. An Unusual Presentation of Multiple Myeloma: Plasmacytic Ascites Complicated by Duodenal Involvement Multiple Myeloma’nın Nadir bir Prezentasyonu: Duedonal Tutulum ile Komplike olan Plazmasitik Asit. Osmangazi Tıp Dergisi. 2017;39(2):60-4.


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