Öz
To evaluate the necessity of antibiotic prophylaxis and to determine the type of microorganisms detected in blood and urine cultures after transrectal ultrasound (TRUS)-guided prostate biopsies are aimed in this study. The study group included 28 men who had undergone TRUS-guided 8 core systematic prostate biopsy. Patients did not use Fleet enema or any antibiotic prophylaxis before the biopsy procedure. Blood cultures were obtained 5 minutes after the biopsy procedure, whereas urine cultures were obtained after 30 minutes. In order to determine infection rates, results of the blood and urine cultures were evaluated and then oral ciprofloxacin was started just after the cultures. Escherischia coli (E. coli) was identified in the urine cultures of 2 (7%) patients. Pathogenic microorganisms were identified in the blood cultures of a total of 8 (28.6%) patients: E.Coli in 7 (25%) patients; and group B streptococcus in 1 (3.5%) patient. After TRUS-guided transrectal prostate biopsy E. coli, were identified at blood cultures with a high rate. These results show that antibiotic prophylaxis which is effective on E. coli is neccessary before TRUS-guided prostate biopsy.
Anahtar Kelimeler
Kaynakça
- 1. Papatheodorou A, Ellinas P, Tandeles S, et al. Transrectal ultrasonography and ultrasound-guided biopsies of the prostate gland: how, when, and where. Curr Probl Diagn Radiol 2005;34:76-83.
- 2. Altman A, Resnick Ml. Ultrasonographically guided biopsy of the prostate gland. J Ultrasound Med 2001;20:159-67.
- 3. Rodriguez LV, Terris MK. Risks and complications of transrectal ultrasound guided prostate needle biopsy. A prospective study and review of the literature. J Urol 1998:160:2115-20.
- 4. Raja J, Ramachandran N, Munneke G, Patel U. Current status of transrectal ultrasound-guided prostate biopsy in the diagnosis of prostate cancer. Clin Radiol 2006;61:142-53.
- 5. Sieber PR, Rommel FM, Agusta VE, Breslin JA, Huffnagle HW, Harpster LE. Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy. J Urol 1997;157:2199-200.
- 6. Öbek C, Önal B, Özkan B, Önder AU, Yalçın V, Solok V. Is periprostatic local anesthesia for transrectal ultrasound guided prostate biopsy associated with increased infectious or hemorrhagic complications? A prospective randomized trial. J Urol 2002;168:558-61.
- 7. Altman A, Resnick M. Ultrasonographically guided biopsy of the prostate gland. J Ultrasound Med 2001;20:159-67.
- 8. Enlund AL, Varenhorst E. Morbidity of ultra-sound-guided transrectal core biopsy of the prostate without prophylactic antibiotic ther- apy. A prospective study in 415 cases. BJU Int 1997;79:777- 80.
- 9. Isen K, Küpeli B, Sinik Z, Sözen Z, Bozkirli I. Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral fluoroquinolones versus trimethoprim-sul-famethoxazole. Int Urol Nephrol 1999;31:491-5.
- 10. Lindert KA, Kabalin JN, Terris MK. Bacteriemia and bacteriuria after transrectal ultrasound guided prostate biopsy. J Urol 2000;164:76-80.
- 11. Aaron M, Rajeev TP, Gupta NP. Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int 2000:85;682-5.
Transrektal Ultrason Rehberliğinde Yapılan Prostat Biyopsileri Öncesinde Antibiyotik Profilaksisi Gerekli midir?
Öz
Transrektal ultrason (TRUS) rehberliğinde yapılan prostat biyopsileri sonrasında kan ve idrar kültürlerinde saptanan mikrorganizma tiplerinin belirlenmesi ve antibiyotik profilaksisinin gerekliliğinin değerlendirilmesi amacı ile çalışmamız planlanmıştır. Çalışma grubunu TRUS-rehberliğinde transrektal yolla 8 kor sistematik prostat biyopsisi uygulanan 28 erkek oluşturmuştur. Hastalara biyopsi işlemi öncesinde Fleet enema veya antibiyotik profilaksisi uygulanmamıştır. Kan kültürleri biyopsi işleminin 5 dakika sonrasında alınırken idrar kültürleri işlemden 30 dakika sonra elde olunmuştur. Enfeksiyon oranlarını belirlemeye yönelik olarak, kan ve idrar kültür sonuçları değerlendirilmiş olup kültürlerden hemen sonra oral siprofloksasin başlanmıştır. Olguların 2’sinin (%7) idrar kültürlerinde Escherischia coli (E. coli) saptanmıştır. 7 (%25) hastada E. coli ve 1 (%.3.5) hastada B grubu streptokok olmak üzere toplam 8 (28.6%) hastanın kan kültürlerinde patojenik mikroorganizmalar belirlenmiştir. TRUS rehberliğinde prostat biyopsisi sonrasında, kan kültürlerinde büyük çoğunluğu E. coli olmak üzere yüksek oranda patojenik mikroorganizmalar saptanmıştır. Bu sonuçlar TRUS rehberliğinde prostat biyopsisi öncesinde özellikle E. coli üzerinde etkili antibiyotik profilaksisinin gerekli olduğunu göstermiştir.
Anahtar Kelimeler
Prostat biyopsisi TRUS komplikasyonlar antibiyotik profilaksisi
Kaynakça
- 1. Papatheodorou A, Ellinas P, Tandeles S, et al. Transrectal ultrasonography and ultrasound-guided biopsies of the prostate gland: how, when, and where. Curr Probl Diagn Radiol 2005;34:76-83.
- 2. Altman A, Resnick Ml. Ultrasonographically guided biopsy of the prostate gland. J Ultrasound Med 2001;20:159-67.
- 3. Rodriguez LV, Terris MK. Risks and complications of transrectal ultrasound guided prostate needle biopsy. A prospective study and review of the literature. J Urol 1998:160:2115-20.
- 4. Raja J, Ramachandran N, Munneke G, Patel U. Current status of transrectal ultrasound-guided prostate biopsy in the diagnosis of prostate cancer. Clin Radiol 2006;61:142-53.
- 5. Sieber PR, Rommel FM, Agusta VE, Breslin JA, Huffnagle HW, Harpster LE. Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy. J Urol 1997;157:2199-200.
- 6. Öbek C, Önal B, Özkan B, Önder AU, Yalçın V, Solok V. Is periprostatic local anesthesia for transrectal ultrasound guided prostate biopsy associated with increased infectious or hemorrhagic complications? A prospective randomized trial. J Urol 2002;168:558-61.
- 7. Altman A, Resnick M. Ultrasonographically guided biopsy of the prostate gland. J Ultrasound Med 2001;20:159-67.
- 8. Enlund AL, Varenhorst E. Morbidity of ultra-sound-guided transrectal core biopsy of the prostate without prophylactic antibiotic ther- apy. A prospective study in 415 cases. BJU Int 1997;79:777- 80.
- 9. Isen K, Küpeli B, Sinik Z, Sözen Z, Bozkirli I. Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral fluoroquinolones versus trimethoprim-sul-famethoxazole. Int Urol Nephrol 1999;31:491-5.
- 10. Lindert KA, Kabalin JN, Terris MK. Bacteriemia and bacteriuria after transrectal ultrasound guided prostate biopsy. J Urol 2000;164:76-80.
- 11. Aaron M, Rajeev TP, Gupta NP. Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int 2000:85;682-5.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Üroloji |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 23 Mart 2008 |
| Yayımlandığı Sayı | Yıl 2008 Cilt: 2 Sayı: 1 |
