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EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON

Yıl 2020, Cilt: 51 Sayı: 1, 46 - 48, 15.01.2020
https://doi.org/10.16948/zktipb.492975

Öz

Hellp syndrome is an atypic, severe and life threatening form of
preeclapmsia, which is usually associated with hemolysis, elevated liver
enzymes and low platelet count. Also it is very important because it causes significantly
maternal and perinatal mortality. It is known that hellp syndrome almost always
occurs after 20 weeks of gestation. But in the presence of some accompanying
diseases, hellp syndrome or severe preeclampsia can occur at earlier
gestational weeks. This may also lead to diagnostic difficulties. In this case,
we described the diagnosis and recovery period of a systemic lupus erytematosus
(SLE) patient who developed hellp syndrome at 17 weeks of gestation. Our experience takes attention that detection
of hellp syndome accompanying diseases like
systemic lupus erytematosus
or acute cholecystitis can be difficult and it can occur distinctly at earlier
weeks of gestation. Also the differential diagnosis is very important in such
cases, because many diseases can mimic hellp syndrome.

Kaynakça

  • 1) Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 2004;103(5 Pt 1):981.
  • 2) Dusse LM, Alpoim PN, Silva JT, Rios DR, Brandão AH, Cabral AC. Revisiting HELLP syndrome. Clin Chim Acta. 2015; 451:117.
  • 3) Stefos T, Plachouras N, Mari G, Cosmi E, Lolis D. A case of partial mole and atypical type I triploidy associated with severe HELLP syndrome at 18 weeks' gestation. Ultrasound in Obstetrics and Gynecology. 2002; Volume 20, Issue 4
  • 4) Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol. 1993;169(4):1000.
  • 5) Oostwaard MF, Ferden L, Laat MW, Duvekot JJ, Erwich JJHM, Bloemenkamp KWM, Bolte AC, Bosma JPF, Koenen SV, Kornelisse RF, Rethans B, Heimel Runnard P, Scheepers HCJ, Ganzevoort W, Mol BWJ, Groot CJ, Gaugler-Seden IPM. Maternal and neonatal outcomes in women with severe early onset pre‐eclampsia before 26 weeks of gestation, a case series. BJOG: An International Journal of Obstetrics & Gynaecology. Volume 124, Issue 9.
  • 6) Rahman TM, Wendon J. “Severe hepatic dysfunction in pregnancy,” Monthly Journal of the Association of Physicians. 2002; vol. 95, no. 6, pp. 343–357.
  • 7) Wada Y, Sakamaki Y, Kobayashi D, Ajiro J, Moro H, Murakami S, Ooki I, Kikuchi A, Takakuwa K, Tanaka K, Sato T, Nakano M, Narita I. HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Intern Med. 2009;48(17):1555-8. Epub 2009 Sep 1.
  • 8) S. Appenzeller, F. H. Souza, A. Wagner Silvia de Souza, Y. Shoenfeld, and J. F. de Carvalho, “HELLP syndrome and its relationship with antiphosphplipid syndrome and antiphospholipid antibodies,” Seminars in Arthritis and Rheumatism. 2011; vol. 41, pp. 517–523.
  • 9) Suzumori N, Obayashi S, Kumagai K, Goto S, Yoshida A, Sugiura-Ogasawara M. Case Rep Med. A Case of Microangiopathic Antiphospholipid-Associated Syndromes during Pregnancy: Review of the Literature. 2012; 2012:827543. doi: 10.1155/2012/827543. Epub 2012 Jun 28.
  • 10) Haram K, Trovik J, Sandset PM, Hordnes K. Severe syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP) in the 18th week of pregnancy associated with the antiphospholipid–antibody syndrome. Acta Obstetricia et Gynecologica Scandinavica.2003; Volume 82, Issue 7 .

17. gebelik haftasında akut kolesistit atağı ve sistemik lupus eritematozus ile birlikte görülen erken başlangıçlı hellp sendromu

Yıl 2020, Cilt: 51 Sayı: 1, 46 - 48, 15.01.2020
https://doi.org/10.16948/zktipb.492975

Öz

Hellp sendromu, preeklampsinin atipik, şiddetli ve hayatı tehdit eden
bir formu olup genellikle hemoliz, yüksek karaciğer enzimleri ve düşük platelet
düzeyleri ile ilişkilidir. Ayrıca, belirgin maternal ve perinatal mortaliteye
de neden olduğundan önemi büyüktür. Hellp sendromunun hemen her zaman gebeliğin
20. haftadan önce meydana geldiği bilinmektedir. Fakat bazı eşlik eden
hastalıkların varlığında hellp sendromu veya şiddetli preeklampsi daha erken
gebelik haftalarında da görülebilir. Bu durum aynı zamanda tanısal zorluğa da
neden olur. Biz bu olguda, 17. Gebelik haftasında hellp sendromu gelişen bir
sistemik lupus eritematozus (SLE) hastasının tanı ve tedavi periodunu anlattık.
Çalışmamız; hellp sendromunun SLE ya da akut kolesistit gibi eşlik eden hastalıklar
varlığında tespit edilmesinin zorluğuna ve şaşırtıcı olarak erken gebelik
haftalarında meydana gelebilmesine dikkat çekmektedir. Aynı zamanda, böyle
olgularda, birçok hastalık hellp sendromunu taklit edebileceğinden ayırıcı tanı
da çok önemlidir.

Kaynakça

  • 1) Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 2004;103(5 Pt 1):981.
  • 2) Dusse LM, Alpoim PN, Silva JT, Rios DR, Brandão AH, Cabral AC. Revisiting HELLP syndrome. Clin Chim Acta. 2015; 451:117.
  • 3) Stefos T, Plachouras N, Mari G, Cosmi E, Lolis D. A case of partial mole and atypical type I triploidy associated with severe HELLP syndrome at 18 weeks' gestation. Ultrasound in Obstetrics and Gynecology. 2002; Volume 20, Issue 4
  • 4) Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol. 1993;169(4):1000.
  • 5) Oostwaard MF, Ferden L, Laat MW, Duvekot JJ, Erwich JJHM, Bloemenkamp KWM, Bolte AC, Bosma JPF, Koenen SV, Kornelisse RF, Rethans B, Heimel Runnard P, Scheepers HCJ, Ganzevoort W, Mol BWJ, Groot CJ, Gaugler-Seden IPM. Maternal and neonatal outcomes in women with severe early onset pre‐eclampsia before 26 weeks of gestation, a case series. BJOG: An International Journal of Obstetrics & Gynaecology. Volume 124, Issue 9.
  • 6) Rahman TM, Wendon J. “Severe hepatic dysfunction in pregnancy,” Monthly Journal of the Association of Physicians. 2002; vol. 95, no. 6, pp. 343–357.
  • 7) Wada Y, Sakamaki Y, Kobayashi D, Ajiro J, Moro H, Murakami S, Ooki I, Kikuchi A, Takakuwa K, Tanaka K, Sato T, Nakano M, Narita I. HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Intern Med. 2009;48(17):1555-8. Epub 2009 Sep 1.
  • 8) S. Appenzeller, F. H. Souza, A. Wagner Silvia de Souza, Y. Shoenfeld, and J. F. de Carvalho, “HELLP syndrome and its relationship with antiphosphplipid syndrome and antiphospholipid antibodies,” Seminars in Arthritis and Rheumatism. 2011; vol. 41, pp. 517–523.
  • 9) Suzumori N, Obayashi S, Kumagai K, Goto S, Yoshida A, Sugiura-Ogasawara M. Case Rep Med. A Case of Microangiopathic Antiphospholipid-Associated Syndromes during Pregnancy: Review of the Literature. 2012; 2012:827543. doi: 10.1155/2012/827543. Epub 2012 Jun 28.
  • 10) Haram K, Trovik J, Sandset PM, Hordnes K. Severe syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP) in the 18th week of pregnancy associated with the antiphospholipid–antibody syndrome. Acta Obstetricia et Gynecologica Scandinavica.2003; Volume 82, Issue 7 .
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumu
Yazarlar

Gamze Nur Cimilli Şenocak 0000-0002-6750-9210

Yayımlanma Tarihi 15 Ocak 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 51 Sayı: 1

Kaynak Göster

APA Cimilli Şenocak, G. N. (2020). EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni, 51(1), 46-48. https://doi.org/10.16948/zktipb.492975
AMA Cimilli Şenocak GN. EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni. Ocak 2020;51(1):46-48. doi:10.16948/zktipb.492975
Chicago Cimilli Şenocak, Gamze Nur. “EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON”. Zeynep Kamil Tıp Bülteni 51, sy. 1 (Ocak 2020): 46-48. https://doi.org/10.16948/zktipb.492975.
EndNote Cimilli Şenocak GN (01 Ocak 2020) EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni 51 1 46–48.
IEEE G. N. Cimilli Şenocak, “EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON”, Zeynep Kamil Tıp Bülteni, c. 51, sy. 1, ss. 46–48, 2020, doi: 10.16948/zktipb.492975.
ISNAD Cimilli Şenocak, Gamze Nur. “EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON”. Zeynep Kamil Tıp Bülteni 51/1 (Ocak 2020), 46-48. https://doi.org/10.16948/zktipb.492975.
JAMA Cimilli Şenocak GN. EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni. 2020;51:46–48.
MLA Cimilli Şenocak, Gamze Nur. “EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON”. Zeynep Kamil Tıp Bülteni, c. 51, sy. 1, 2020, ss. 46-48, doi:10.16948/zktipb.492975.
Vancouver Cimilli Şenocak GN. EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni. 2020;51(1):46-8.