Yıl 2017, Cilt 2, Sayı 3, Sayfalar 16 - 21 2017-12-28

The prevalence of thyroid nodules in children with family history for nodular goiter
Ailesinde nodüler guatr olan çocukların tiroid lezyon prevalansı

Zuhal Aşık [1] , Hakan Aylanç [2]

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Introduction: There is insufficient study on the genetic clustering of nodular goiter. Although twin studies have proved genetic clustering, there is no prospective study on this topic. The aim of this study is to investigate the existence of familial clustering by evaluating the prevalence of thyroid nodules in the children of families with nodular goiter.

Methods: The prevalence of thyroid nodules was calculated by evaluating the thyroid ultrasound results of children from families with and without nodular goiter.

Results: Nodular goiter was detected in 5 children (3.4%), 2 (2.5%) from families with nodular goiter history and 3 (4.7%) from the control group. There was no statistically significant difference between these two groups.

Conclusions: This is the first prospective study to investigate the familial aspect of nodular goiter disease. In our study, children with nodular goiter were the target group. Following statistical analysis, clustering of nodular goiter was observed in the children of patients with multinodular goiter.


Giriş: Nodüler guatrın genetik olarak kümelenmesi ile ilgili yeterli çalışma yoktur. Her ne kadar ikiz çalışmaları genetik bir kümelenme göstermişse de, bu konuyla ilgili yapılmış prospektif bir çalışma yoktur. Bu çalışmanın amacı ailesinde nodüler guatrı olan çocuklardaki nodül prevelansının değerlendirilerek ailesel kümelenmenin varlığının araştırılmasıdır.

Yöntem: Ailesinde nodüler guatr tespit edilen ve edilmeyen çocukların tiroit ultrasonu ile değerlendirilerek nodül prevelansı hesaplanmıştır.

Bulgular: Tüm çocukların 5’inde (%3,4) nodüler guatr saptandı. Ailesinde nodüler guatr öyküsü olan çocukların 2’sinde (%2,5), kontrol grubundaki çocukların 3’ünde (%4,7) nodüler guatr tespit edildi. 2 grup arasında istatistiksel olarak anlamlı fark saptanmadı.

Sonuç: Bu çalışma nodüler guatr hastalığının ailesel yönünü araştıran ilk prospektif çalışmadır. Çalışmamızda nodüler guatrlı hastaların çocuk kitlesi hedeflenmiştir. Yapılan istatistiksel analiz sonucunda MNG’lı hastaların çocuklarında nodüler guatrın kümelenmediği izlenmiştir.

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Konular Sağlık Bilimleri
Yayımlanma Tarihi Dec 2017
Dergi Bölümü Araştırma Makalesi (Original Article)
Yazarlar

Orcid: 0000-0003-3062-6066
Yazar: Zuhal Aşık
E-posta: draylanc@hotmail.com
Kurum: Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı, Çanakkale
Ülke: Turkey


Orcid: 0000-0002-8907-3809
Yazar: Hakan Aylanç (Sorumlu Yazar)
E-posta: draylanc@hotmail.com
Kurum: Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı, Çanakkale
Ülke: Turkey


Bibtex @araştırma makalesi { fppc333879, journal = {Family Practice and Palliative Care}, issn = {2458-8865}, address = {Yusuf Haydar ERTEKİN}, year = {2017}, volume = {2}, pages = {16 - 21}, doi = {10.22391/920.333879}, title = {The prevalence of thyroid nodules in children with family history for nodular goiter}, key = {cite}, author = {Aşık, Zuhal and Aylanç, Hakan} }
APA Aşık, Z , Aylanç, H . (2017). The prevalence of thyroid nodules in children with family history for nodular goiter. Family Practice and Palliative Care, 2 (3), 16-21. Retrieved from http://www.fppc.com.tr/issue/31091/333879
MLA Aşık, Z , Aylanç, H . "The prevalence of thyroid nodules in children with family history for nodular goiter". Family Practice and Palliative Care 2 (2017): 16-21 <http://www.fppc.com.tr/issue/31091/333879>
Chicago Aşık, Z , Aylanç, H . "The prevalence of thyroid nodules in children with family history for nodular goiter". Family Practice and Palliative Care 2 (2017): 16-21
RIS TY - JOUR T1 - The prevalence of thyroid nodules in children with family history for nodular goiter AU - Zuhal Aşık , Hakan Aylanç Y1 - 2017 PY - 2017 N1 - DO - T2 - Family Practice and Palliative Care JF - Journal JO - JOR SP - 16 EP - 21 VL - 2 IS - 3 SN - 2458-8865-2459-1505 M3 - UR - Y2 - 2017 ER -
EndNote %0 Family Practice and Palliative Care The prevalence of thyroid nodules in children with family history for nodular goiter %A Zuhal Aşık , Hakan Aylanç %T The prevalence of thyroid nodules in children with family history for nodular goiter %D 2017 %J Family Practice and Palliative Care %P 2458-8865-2459-1505 %V 2 %N 3 %R %U