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Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages

Yıl 2021, , 35 - 42, 03.04.2021

Dilek Atik , Basar Cander , Ramiz Yazıcı , Bensu Bulut , Ramazan Ünal , Eren Sert

https://doi.org/10.22391/fppc.817258

Öz

Introduction: Intracerebral Spontaneous Hemorrhage (ISH) is a sudden hemorrhage into the brain parenchyma as a result of a rupture of the cerebral vessels that are not related to traumas. The purpose of the present study was to evaluate the relation of mortality with Platelet Volume Index (PVI) scoring systems, which have been reported in a small number of studies in terms of blood RDW, MPV, platelet and intracranial hemorrhages in patients diagnosed with intraparenchymal hemorrhage in Emergency Departments.
Methods: This study was performed retrospectively by examining patient files of patients who came to Emergency Medicine Clinic between 01.01.2019-31.12.2019. As a control group for comparison of blood parameters, blood parameters of 72 patients suitable for the same age population, without intraparenchymal haemorrhage.
Results: A total of 54.10% (n=85) intraparenchymal bleeding patients (IPC) and 45.90% (n=72) healthy control groups (HCG) were included in the study. There was no statistically significant difference between the clinical results of IPC groups in terms of mortality of RDW parameter and MPV parameter (p=0.930; p=0.118). When PVI ratio was evaluated in IPC group and HCG; the mean PVI (MPV/Platelet ratio) in the IPC group was 4.37±1.66, and the PVI (MPV/Platelet ratio) in the HCG was 3.89±1.02.A statistically significant difference was found between the PVI in the patient group and the HCG.A statistically significant difference was found between the PVI ratio clinical results of the patients with IPC (p=0.043).
Conclusion: Spontaneous Intraparenchymal hemorrhage are among the leading causes of stroke-induced mortality and disability. The Hemphill Score and hemorrhage volume are important factors in mortality evaluation in intraparenchymal hemorrhage. There are not many studied conducted on Platelet Volume Index, and it is an important marker in predicting mortality, especially in these patients. 

Anahtar Kelimeler

Intraparenchymal haemorrhage Mean platelet volume Red cell distribution width

Kaynakça

  • 1. Hankey GJ. Stroke. The Lancet 2017; 389(10069): 641-54. https://doi.org/10.1016/S0140-6736(16)30962-X.
  • 2. Lee WC, Joshi AV, Wang Q, Pashos CL, Christensen MC. Morbidity and mortality among elderly Americans with different stroke subtypes. Cerebrovasc Dis 2007;23(2):221-8. https://doi.org/10.1007/BF02849893.
  • 3. Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, et al. ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network. Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375(11):1033-43. https://doi.org/10.1056/NEJMoa1603460.
  • 4. Satopaa, J, Mustanoja S, Meretoja A, Putaala J, Markku Kaste M, Mika Niemela M, et al. Comparison of all 19 published prognostic scores for intracerebral hemorrhage. J Neurol Sci 2017;379: 103-8. https://doi.org/10.1016/j.jns.2017.05.034.
  • 5. Oge DD, Arsava EM, Pektezel MY, Yildiz OK, Topcuoglu MA. Prediction of early prognosis in intracerebral hematomas: Stich-2 prognosis score against hemphill score. Turk J Cerebrovasc Dis 2019; 25(2): 106-12. https://doi.org/10.5505/tbdhd.2019.46320.
  • 6. Suzuki S, Kelley RE, Dandapani BK, Reyes-Iglesias Y, Dietrich WD, Duncan RC. Acute leukocyte and temperature response in hypertensive intracerebral hemorrhage. Stroke 1995;26(6):1020–3. https://doi.org/10.1161/01.STR.26.6.1020.
  • 7. Behrouz R, Hafeez S, Miller CM. Admission leukocytosis in intracerebral hemorrhage: associated factors and prognostic implications. Neurocrit Care 2015;23(3):370–3. https://doi.org/10.1007/s12028-015-0128-7.
  • 8. Aronowski J, Zhao X. Molecular pathophysiology of cerebral hemorrhage: Secondary brain injury. Stroke 2011; 42: (6):1781-6. https://doi.org/10.1161/STROKEAHA.110.596718.
  • 9. Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation 2008;117(2):163–8. https://doi.org/10.1161/CIRCULATIONAHA.107.727545.
  • 10. Ye Z, Smith C, Kullo IJ. Usefulness of red cell distribution width to predict mortality in patients with peripheral artery disease. Am J Cardiol 2011;107(8):1241-5. https://doi.org/10.1016/j.amjcard.2010.12.023.
  • 11. Ani C, Ovbiagele B. Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci 2009;277(1-2):103-8. https://doi.org/10.1016/j.jns.2008.10.024.
  • 12. Zorlu A, Bektasoglu G, Guven FMK, Dogan OT, Gucuk E, Ege RM, et al. Usefulness of admission red cell distribution width as a predictor of early mortality in patients with acute pulmonary embolism. Am J Cardiol 2012 ;109(1):128-34. https://doi.org/10.1016/j.amjcard.2011.08.015.
  • 13. Lindemann S, Kramer B, Seizer P, Gawaz M. Platelets, inflammation and atherosclerosis. J Thromb Haemost 2007; 5(Suppl.1): 203–11. https://doi.org/10.1111/j.1538-7836.2007.02517.x.
  • 14. Tedgui A, Mallat Z. Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways. Physiol Rev 2006; 86(2): 515-81. https://doi.org/10.1152/physrev.00024.2005.
  • 15. Ziai WC, Torbey MT, Kickler TS, Oh S, Bhardwaj A, Wityk RJ. Platelet count and function in spontaneous intracerebral hemorrhage. J Stroke Cerebrovasc Dis 2003; 12(4): 201-6. https://doi.org/10.1016/S1052-3057(03)00075-2.
  • 16. Arikanoglu A, Cevik MU, Uzar E, Acar A, Akil E, Ekici F, Tasdemir N. The increase of the mean platelet volume in patients with intracerebral haemorrhage. Turk J Neurol 2012; 18:54-6. https://doi.org/10.4274/Tnd.05325.
  • 17. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27(8):1304-5. https://doi.org/10.1161/01.str.27.8.1304.
  • 18. Yuksel O, Helvaci K, Basar O, Koklu S, Caner S, Helvaci N, Abayli E, Altiparmak E. An overlooked indicator of disease activity in ulcerative colitis: mean platelet volume. Platelets 2009; 20(4): 277-81. https://doi.org/10.1080/09537100902856781.
  • 19. Nadiech AM, Bernstein RA, Levasseur K, Bassin SL, Bendok BR, Batjer HH, et al. Platelet activity and outcome after intracerebral hemorrhage. Ann Neurol 2009;65(3):352-6. https://doi.org/10.1002/ana.21618.
  • 20. Brummitt DR, Barker HF. The determination of a reference range for new platelet parameters produced by the Bayer ADVIA 120 full blood count analyser. Clin Lab Haematol 2000;22(2):103-7. https://doi.org/10.1046/j.1365-2257.2000.00285.x.
  • 21. Zaccardi F, Rocca B, Pitocco D, Tanese L, Rizzi A, Ghirlanda G. Platelet mean volume, distribution width, and count in type 2 diabetes, impaired fasting glucose, and metabolic syndrome: a meta-analysis. Diabetes Me-tab Res Rev 2015;31(4):402-10. https://doi.org/10.1002/dmrr.2625.
  • 22. Kaplan ZS, Jackson SP. The role of platelets in atherothrombosis. Hematology Am Soc Hematol Educ Program 2011;2011:51-61. https://doi.org/10.1182/asheducation-2011.1.51.
  • 23. Hemphill, JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke 2001; 32(4): 891-7. https://doi.org/10.1161/01.STR.32.4.891.
  • 24. Dundar TT, Kitis S , Abdallah A , Yurtsever I , Gulen B. Evaluation of the platelet volume index as a prognostic factor after aneurysmal subarachnoid hemorrhage. J Surg Med 2019;3(9):685-8. https://doi.org/10.28982/josam.567491.
  • 25. Kase CS, Kaplan LR. Intracerebral hemorrhage. Boston: Butterworth-Heinemann. 1994. https://doi.org/10.1016/B978-0-7506-9308-0.50024-5.
  • 26. Cheung RT, Zou LY. Use of the original, modified, or new intracerebral hemorrhage score to predict mortality and morbidity after intracerebral hemorrhage. Stroke 2003;34(7):1717-22. https://doi.org/10.1161/01.STR.0000078657.22835.B9.
  • 27. Fukuta H, Nobuyuki O, Mukai S, Saeki T, Asada K, Wakami K, et al. Elevated plasma levels of B-Type Natriuretic Peptide but Not C-Reactive Protein are associated with higher red cell distribution width in patients with coronary artery disease. Int Heart J 2009; 50: 301-12. https://doi.org/10.1536/ihj.50.301.
  • 28. Kase CS, Mohr JP, Caplan LR. Intracerebral hemorrhage. In: Mohr JP,Wolf PA, Grotta JC, Moskowitz MA, Mayberg MR, von Kummer R(eds). Stroke Elsevier 2011: 327-6. https://doi.org/10.1016/B0-44-306600-0/50017-1.
  • 29. Paulus EM, Weinberg JA, Magnotti LJ, Sharpe JP, Schroeppel TJ, Fabian TC, Croce MA. Admission red cell distribution width: A novel predictor of massive transfusion after injury. Am Surg 2014;80(7): 685-9. https://doi.org/10.1177/000313481408000724.
  • 30. Kim CH, Park JT, Kim EJ, et al. An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock. Critical Care 2013;17(6):R282. https://doi.org/10.1186/cc13145.
  • 31. Chugh C, Nyirjesy SC, Nawalinski KP. Red blood cell distribution width is associated with poor clinical outcome after subarachnoid hemorrhage: a pilot study. Neurocrit Care 2015; 23(2): 217-24. https://doi.org/10.1007/s12028-015-0117-x.
  • 32. Erdogan V, Avci A. Factors affecting mortality in subarachnoid hemorrhage. Med J Bakirkoy 2017;13(4):175-83. https://doi.org/10.5350/BTDMJB201713407.
  • 33. Oh HJ, Park JT, Kim JK, Yoo DE, Kim SJ, Han SH, et al. Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy. Nephrol Dial Transplant 2012;27(2):589-94. https://doi.org/10.1093/ndt/gfr307.
  • 34. Jennett B, Bond M. Assessment of outcome after severe brain damage. Lancet 1975;1(7905):480-4. https://doi.org/10.1016/S0140-6736(75)92830-5.
  • 35. Naidech AM, Jovanovic B, Liebling S, Garg RK, Bassin SL, Bendok BR, Bernstein RA, Alberts MJ, Batjer HH. Reduced platelet activity is associated with early clot growth and worse 3-month outcome after intracerebral hemorrhage. Stroke. 2009 Jul;40(7):2398-401. https://doi.org/10.1161/STROKEAHA.109.550939.
  • 36. Kapsoritakis AN, Koukourakis MI, Sfiridaki A, Potamianos SP, Kosmadaki MG, Koutroubakis IE, Kouroumalis EA. Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol 2001;96:776-81. https://doi.org/10.1111/j.1572-0241.2001.03621.x.
  • 37. Greisenegger S, Endler G, Hsieh K, Tentschert S, Mannhalter C, Lalouschek W. Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events? Stroke 2004;35(7):1688-91. https://doi.org/10.1161/01.STR.0000130512.81212.a2.
  • 38. Gonzalez-Duarte A, Garcıa-Ramos GS, Valdes-Ferrer SI, Cantu-Brito C. Clinical description of intracranial hemorrhage associated with bleeding disorders. J Stroke Cerebrovasc Dis 2008;17(4):204-7. https://doi.org/10.1016/j.jstrokecerebrovasdis.2008.02.008.
  • 39. Bath P, Algert C, Chapman N, Neal B. Progress Collaborative Group. Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke 2004; 35(3):622–6. https://doi.org/10.1161/01.STR.0000116105.26237.EC.
  • 40. Tuzcu K, Isil Davarci I, Hakimoglu S, Yengil E, Aras M, Sari A, Kekec L, Dikey I. Evaluatıon of neutrophil/lymphocyte ratio and mean platelet volume in patients with acute and chronic subdural hemorrhage. MKU Med J 2013;4(14):23-30.
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  • 42. Teo M, Guilfoyle MR, Turner C, Kirkpatrick PJ, Turnel CL, Murray GD, et al. What factors determine treatment outcome in aneurysmal subarachnoid haemorrhage in the modern era? A post-hoc STASH analysis. World Neurosurg 2017;105: 270-81. https://doi.org/10.1016/j.wneu.2017.05.005

Spontan intraparankimal kanamalarda Platelet Volüm İndex, MPV ve RDW değerlerinin mortalite ile ilişkisinin değerlendirilmesi

Yıl 2021, , 35 - 42, 03.04.2021

Dilek Atik , Basar Cander , Ramiz Yazıcı , Bensu Bulut , Ramazan Ünal , Eren Sert

https://doi.org/10.22391/fppc.817258

Öz

Giriş: Spontan İntraserebral hemoraji (İSH), aniden oluşan ,travmaya bağlı olmayan beyin damarları rüptürü sonucu beyin parankimi içine kanamalardır. Bu çalışma ile intraparankimal kanama tanısı alan hastalarında kan RDW, MPV, platelet ve şu ana kadar intrakraniyal hemorajilerde az sayıda çalışma bildirilen platelet volüm indexinin (PVI) skorlama sistemleri ile birlikte mortalite ilişkisini değerlendirmesini amaçladık.
Yöntem: Bu çalışma 01.01.2019-31.12.2019 tarihleri arasında Acil Tıp Kliniğine gelen hastaların hasta dosyaları incelenerek retrospektif olarak yapıldı. Kan parametrelerinin karşılaştırılması için kontrol grubu olarak, intraparankimal kanama olmayan aynı yaş popülasyonuna uygun 72 hastanın kan parametreleri değerlendirildi. Klinik sonuçlara göre RDW, MPV, Platelet ve PVI kan parametreleri değerlendirildi.
Bulgular: Çalışmaya toplam %54,10 (n = 85) intraparankimal kanama hastası (IPK) ve %45,90 (n = 72) sağlıklı kontrol grubu (SKG) dahil edildi. IPK gruplarının klinik sonuçları arasında RDW parametresi ve MPV parametresinin mortalitesi açısından istatistiksel olarak anlamlı bir fark yoktu (p=0,930;p=0,118). IPK grubu ve SKG'de PVI oranı değerlendirildiğinde; ortalama PVI (MPV/Trombosit oranı) IPK grubu 4,37± 1,66 ve SKG'deki PVI (MPV/Trombosit oranı) 3,89 ± 1,02 idi. Hasta grubundaki PVI oranı ile SKG arasında istatistiksel olarak anlamlı bir fark bulundu. IPC'li hastaların PVI oranı klinik sonuçları değerlendirildi; mortalite açısından gruplar arasında istatistiksel olarak anlamlı fark vardı (p=0,043).
Sonuç: Spontan intraparankimal kanama, inmeye bağlı mortalite ve özürlülüğün önde gelen nedenleri arasındadır. Hemphill Score ve kanama hacmi intraparankimal kanamada mortalite değerlendirmesinde önemli faktörlerdir. Platelet Hacim İndeksi üzerine yapılmış çok fazla çalışma yoktur ve özellikle bu hastalarda mortaliteyi öngörmede önemli bir belirteçtir.

Anahtar Kelimeler

İntraparankimal kanama Ortalama trombosit hacmi Kırmızı hücre dağılım genişliği

Kaynakça

  • 1. Hankey GJ. Stroke. The Lancet 2017; 389(10069): 641-54. https://doi.org/10.1016/S0140-6736(16)30962-X.
  • 2. Lee WC, Joshi AV, Wang Q, Pashos CL, Christensen MC. Morbidity and mortality among elderly Americans with different stroke subtypes. Cerebrovasc Dis 2007;23(2):221-8. https://doi.org/10.1007/BF02849893.
  • 3. Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, et al. ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network. Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375(11):1033-43. https://doi.org/10.1056/NEJMoa1603460.
  • 4. Satopaa, J, Mustanoja S, Meretoja A, Putaala J, Markku Kaste M, Mika Niemela M, et al. Comparison of all 19 published prognostic scores for intracerebral hemorrhage. J Neurol Sci 2017;379: 103-8. https://doi.org/10.1016/j.jns.2017.05.034.
  • 5. Oge DD, Arsava EM, Pektezel MY, Yildiz OK, Topcuoglu MA. Prediction of early prognosis in intracerebral hematomas: Stich-2 prognosis score against hemphill score. Turk J Cerebrovasc Dis 2019; 25(2): 106-12. https://doi.org/10.5505/tbdhd.2019.46320.
  • 6. Suzuki S, Kelley RE, Dandapani BK, Reyes-Iglesias Y, Dietrich WD, Duncan RC. Acute leukocyte and temperature response in hypertensive intracerebral hemorrhage. Stroke 1995;26(6):1020–3. https://doi.org/10.1161/01.STR.26.6.1020.
  • 7. Behrouz R, Hafeez S, Miller CM. Admission leukocytosis in intracerebral hemorrhage: associated factors and prognostic implications. Neurocrit Care 2015;23(3):370–3. https://doi.org/10.1007/s12028-015-0128-7.
  • 8. Aronowski J, Zhao X. Molecular pathophysiology of cerebral hemorrhage: Secondary brain injury. Stroke 2011; 42: (6):1781-6. https://doi.org/10.1161/STROKEAHA.110.596718.
  • 9. Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation 2008;117(2):163–8. https://doi.org/10.1161/CIRCULATIONAHA.107.727545.
  • 10. Ye Z, Smith C, Kullo IJ. Usefulness of red cell distribution width to predict mortality in patients with peripheral artery disease. Am J Cardiol 2011;107(8):1241-5. https://doi.org/10.1016/j.amjcard.2010.12.023.
  • 11. Ani C, Ovbiagele B. Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci 2009;277(1-2):103-8. https://doi.org/10.1016/j.jns.2008.10.024.
  • 12. Zorlu A, Bektasoglu G, Guven FMK, Dogan OT, Gucuk E, Ege RM, et al. Usefulness of admission red cell distribution width as a predictor of early mortality in patients with acute pulmonary embolism. Am J Cardiol 2012 ;109(1):128-34. https://doi.org/10.1016/j.amjcard.2011.08.015.
  • 13. Lindemann S, Kramer B, Seizer P, Gawaz M. Platelets, inflammation and atherosclerosis. J Thromb Haemost 2007; 5(Suppl.1): 203–11. https://doi.org/10.1111/j.1538-7836.2007.02517.x.
  • 14. Tedgui A, Mallat Z. Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways. Physiol Rev 2006; 86(2): 515-81. https://doi.org/10.1152/physrev.00024.2005.
  • 15. Ziai WC, Torbey MT, Kickler TS, Oh S, Bhardwaj A, Wityk RJ. Platelet count and function in spontaneous intracerebral hemorrhage. J Stroke Cerebrovasc Dis 2003; 12(4): 201-6. https://doi.org/10.1016/S1052-3057(03)00075-2.
  • 16. Arikanoglu A, Cevik MU, Uzar E, Acar A, Akil E, Ekici F, Tasdemir N. The increase of the mean platelet volume in patients with intracerebral haemorrhage. Turk J Neurol 2012; 18:54-6. https://doi.org/10.4274/Tnd.05325.
  • 17. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27(8):1304-5. https://doi.org/10.1161/01.str.27.8.1304.
  • 18. Yuksel O, Helvaci K, Basar O, Koklu S, Caner S, Helvaci N, Abayli E, Altiparmak E. An overlooked indicator of disease activity in ulcerative colitis: mean platelet volume. Platelets 2009; 20(4): 277-81. https://doi.org/10.1080/09537100902856781.
  • 19. Nadiech AM, Bernstein RA, Levasseur K, Bassin SL, Bendok BR, Batjer HH, et al. Platelet activity and outcome after intracerebral hemorrhage. Ann Neurol 2009;65(3):352-6. https://doi.org/10.1002/ana.21618.
  • 20. Brummitt DR, Barker HF. The determination of a reference range for new platelet parameters produced by the Bayer ADVIA 120 full blood count analyser. Clin Lab Haematol 2000;22(2):103-7. https://doi.org/10.1046/j.1365-2257.2000.00285.x.
  • 21. Zaccardi F, Rocca B, Pitocco D, Tanese L, Rizzi A, Ghirlanda G. Platelet mean volume, distribution width, and count in type 2 diabetes, impaired fasting glucose, and metabolic syndrome: a meta-analysis. Diabetes Me-tab Res Rev 2015;31(4):402-10. https://doi.org/10.1002/dmrr.2625.
  • 22. Kaplan ZS, Jackson SP. The role of platelets in atherothrombosis. Hematology Am Soc Hematol Educ Program 2011;2011:51-61. https://doi.org/10.1182/asheducation-2011.1.51.
  • 23. Hemphill, JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke 2001; 32(4): 891-7. https://doi.org/10.1161/01.STR.32.4.891.
  • 24. Dundar TT, Kitis S , Abdallah A , Yurtsever I , Gulen B. Evaluation of the platelet volume index as a prognostic factor after aneurysmal subarachnoid hemorrhage. J Surg Med 2019;3(9):685-8. https://doi.org/10.28982/josam.567491.
  • 25. Kase CS, Kaplan LR. Intracerebral hemorrhage. Boston: Butterworth-Heinemann. 1994. https://doi.org/10.1016/B978-0-7506-9308-0.50024-5.
  • 26. Cheung RT, Zou LY. Use of the original, modified, or new intracerebral hemorrhage score to predict mortality and morbidity after intracerebral hemorrhage. Stroke 2003;34(7):1717-22. https://doi.org/10.1161/01.STR.0000078657.22835.B9.
  • 27. Fukuta H, Nobuyuki O, Mukai S, Saeki T, Asada K, Wakami K, et al. Elevated plasma levels of B-Type Natriuretic Peptide but Not C-Reactive Protein are associated with higher red cell distribution width in patients with coronary artery disease. Int Heart J 2009; 50: 301-12. https://doi.org/10.1536/ihj.50.301.
  • 28. Kase CS, Mohr JP, Caplan LR. Intracerebral hemorrhage. In: Mohr JP,Wolf PA, Grotta JC, Moskowitz MA, Mayberg MR, von Kummer R(eds). Stroke Elsevier 2011: 327-6. https://doi.org/10.1016/B0-44-306600-0/50017-1.
  • 29. Paulus EM, Weinberg JA, Magnotti LJ, Sharpe JP, Schroeppel TJ, Fabian TC, Croce MA. Admission red cell distribution width: A novel predictor of massive transfusion after injury. Am Surg 2014;80(7): 685-9. https://doi.org/10.1177/000313481408000724.
  • 30. Kim CH, Park JT, Kim EJ, et al. An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock. Critical Care 2013;17(6):R282. https://doi.org/10.1186/cc13145.
  • 31. Chugh C, Nyirjesy SC, Nawalinski KP. Red blood cell distribution width is associated with poor clinical outcome after subarachnoid hemorrhage: a pilot study. Neurocrit Care 2015; 23(2): 217-24. https://doi.org/10.1007/s12028-015-0117-x.
  • 32. Erdogan V, Avci A. Factors affecting mortality in subarachnoid hemorrhage. Med J Bakirkoy 2017;13(4):175-83. https://doi.org/10.5350/BTDMJB201713407.
  • 33. Oh HJ, Park JT, Kim JK, Yoo DE, Kim SJ, Han SH, et al. Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy. Nephrol Dial Transplant 2012;27(2):589-94. https://doi.org/10.1093/ndt/gfr307.
  • 34. Jennett B, Bond M. Assessment of outcome after severe brain damage. Lancet 1975;1(7905):480-4. https://doi.org/10.1016/S0140-6736(75)92830-5.
  • 35. Naidech AM, Jovanovic B, Liebling S, Garg RK, Bassin SL, Bendok BR, Bernstein RA, Alberts MJ, Batjer HH. Reduced platelet activity is associated with early clot growth and worse 3-month outcome after intracerebral hemorrhage. Stroke. 2009 Jul;40(7):2398-401. https://doi.org/10.1161/STROKEAHA.109.550939.
  • 36. Kapsoritakis AN, Koukourakis MI, Sfiridaki A, Potamianos SP, Kosmadaki MG, Koutroubakis IE, Kouroumalis EA. Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol 2001;96:776-81. https://doi.org/10.1111/j.1572-0241.2001.03621.x.
  • 37. Greisenegger S, Endler G, Hsieh K, Tentschert S, Mannhalter C, Lalouschek W. Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events? Stroke 2004;35(7):1688-91. https://doi.org/10.1161/01.STR.0000130512.81212.a2.
  • 38. Gonzalez-Duarte A, Garcıa-Ramos GS, Valdes-Ferrer SI, Cantu-Brito C. Clinical description of intracranial hemorrhage associated with bleeding disorders. J Stroke Cerebrovasc Dis 2008;17(4):204-7. https://doi.org/10.1016/j.jstrokecerebrovasdis.2008.02.008.
  • 39. Bath P, Algert C, Chapman N, Neal B. Progress Collaborative Group. Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke 2004; 35(3):622–6. https://doi.org/10.1161/01.STR.0000116105.26237.EC.
  • 40. Tuzcu K, Isil Davarci I, Hakimoglu S, Yengil E, Aras M, Sari A, Kekec L, Dikey I. Evaluatıon of neutrophil/lymphocyte ratio and mean platelet volume in patients with acute and chronic subdural hemorrhage. MKU Med J 2013;4(14):23-30.
  • 41. Ray B, Tinsley L, Ford L, Thompson DM, Sidorov EV, Bohnstedt, BN. Trends of platelet volume index predicts delayed cerebral ischemia after subarachnoid hemorrhage. World Neurosurg 2018;111;e624–e31. https://doi.org/10.1016/j.wneu.2017.12.131.
  • 42. Teo M, Guilfoyle MR, Turner C, Kirkpatrick PJ, Turnel CL, Murray GD, et al. What factors determine treatment outcome in aneurysmal subarachnoid haemorrhage in the modern era? A post-hoc STASH analysis. World Neurosurg 2017;105: 270-81. https://doi.org/10.1016/j.wneu.2017.05.005
Toplam 42 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Bölüm Araştırma Makalesi (Original Article)
Yazarlar

Dilek Atik 0000-0002-3270-8711

Basar Cander 0000-0002-3308-5843

Ramiz Yazıcı 0000-0001-9210-914X

Bensu Bulut 0000-0002-5629-3143

Ramazan Ünal 0000-0002-6181-4644

Eren Sert 0000-0001-6848-6877

Yayımlanma Tarihi 3 Nisan 2021
Gönderilme Tarihi 27 Ekim 2020
Kabul Tarihi 3 Şubat 2021
Yayımlandığı Sayı Yıl 2021

Kaynak Göster

APA Atik, D., Cander, B., Yazıcı, R., Bulut, B., vd. (2021). Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages. Family Practice and Palliative Care, 6(1), 35-42. https://doi.org/10.22391/fppc.817258
AMA Atik D, Cander B, Yazıcı R, Bulut B, Ünal R, Sert E. Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages. Fam Pract Palliat Care. Nisan 2021;6(1):35-42. doi:10.22391/fppc.817258
Chicago Atik, Dilek, Basar Cander, Ramiz Yazıcı, Bensu Bulut, Ramazan Ünal, ve Eren Sert. “Evaluation of the Relation of Platelet Volume Index, MPV and RDW Values With Mortality in Spontaneous Intraparenchymal Hemorrhages”. Family Practice and Palliative Care 6, sy. 1 (Nisan 2021): 35-42. https://doi.org/10.22391/fppc.817258.
EndNote Atik D, Cander B, Yazıcı R, Bulut B, Ünal R, Sert E (01 Nisan 2021) Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages. Family Practice and Palliative Care 6 1 35–42.
IEEE D. Atik, B. Cander, R. Yazıcı, B. Bulut, R. Ünal, ve E. Sert, “Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages”, Fam Pract Palliat Care, c. 6, sy. 1, ss. 35–42, 2021, doi: 10.22391/fppc.817258.
ISNAD Atik, Dilek vd. “Evaluation of the Relation of Platelet Volume Index, MPV and RDW Values With Mortality in Spontaneous Intraparenchymal Hemorrhages”. Family Practice and Palliative Care 6/1 (Nisan 2021), 35-42. https://doi.org/10.22391/fppc.817258.
JAMA Atik D, Cander B, Yazıcı R, Bulut B, Ünal R, Sert E. Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages. Fam Pract Palliat Care. 2021;6:35–42.
MLA Atik, Dilek vd. “Evaluation of the Relation of Platelet Volume Index, MPV and RDW Values With Mortality in Spontaneous Intraparenchymal Hemorrhages”. Family Practice and Palliative Care, c. 6, sy. 1, 2021, ss. 35-42, doi:10.22391/fppc.817258.
Vancouver Atik D, Cander B, Yazıcı R, Bulut B, Ünal R, Sert E. Evaluation of the relation of Platelet Volume Index, MPV and RDW values with mortality in spontaneous intraparenchymal hemorrhages. Fam Pract Palliat Care. 2021;6(1):35-42.

Family Practice and Palliative Care      ISSN 2458-8865       E-ISSN 2459-1505