Year 2017, Volume 2 , Issue 1, Pages 9 - 16 2017-04-25

Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer
Larenks kanserli hastalarda adjuvant radyoterapinin ses ve yaşam kalitesi ile ilişkisi

Medine Kara [1] , Hülya Ertekin [2] , Başak Şahin [3] , Sibel Cevizci [4] , Fevzi Sefa Dereköy [5]


Introduction: To evaluate the effect of surgery type and adjuvant radiotherapy (RT) on voice quality and quality of life in patients with larynx cancer.

Methods: 38 patients with larynx cancer (37 males, 1 female; mean age 63.6 ± 9.63 years) were included in this study. The parameters including tumor localization, TNM staging, and type of surgery performed, adjuvant/primary RT intake and recurrence were recorded. All participants filled voice handicap index (VHI-10) and University of Washington Quality of Life Questionnaire version-IV (UWQOL-4). Voice analysis was performed by Xion Endo Strop-DX system. Questionnaire scores and voice parameters were compared between groups.

Results: There was a statistically significant low mean values of VHI detected within the group of stripping/cordectomy compared to groups of partial or total laryngectomy. In the group without RT, the mean values of SPLmin, MPT, pain, appearance, swallowing and chewing subgroups of UWQOL scale were higher than the group treated with RT. There was a negative correlation identified between VHI and QOL parameters.

Conclusion: In advanced stage larynx cancer, increased surgical manipulation and adjuvant RT requirements decrease QOL. As a result early diagnosis of disease and treatment is very important. As subjective voice quality increases QOL scores rise, indicating the importance of referring patients for voice therapy and psychotherapy after treatment.

Giriş: Bu çalışmanın amacı larenks kanserli hastalarda ameliyat tipi ve adjuvant radyoterapinin (RT) hastaların ses ve yaşam kalitesi üzerindeki etkisini araştırmaktır.

Yöntem: Larenks kanseri nedeni ile ameliyat edilen 38 hasta (37 erkek, 1 kadın; ort. yaş 63,6 ± 9,63  yıl) bu çalışmaya dahil edildi. Tanı esnasındaki tümör lokalizasyonu, TNM evrelemesi, uygulanan ameliyat tipi, adjuvant/primer RT alımı, nüks varlığı ve postoperatif takip süresi kaydedildi. Tüm katılımcıların öznel ses handikap indeksi (VHI-10) ve Washington Üniversitesi Yaşam Kalitesi Anketi versiyon-IV (UWQOL-4) ile ses ve yaşam kalitesi skorları hesaplandı. Ses analizi Xion Endo Strop-DX sistemi ile gerçekleştirildi. Anket skorları ve ses parametreleri gruplar arasında karşılaştırıldı.

Bulgular: VHI ortalamaları stripping/kordektomi grubunda, parsiyel veya total larenjektomi gruplarına göre istatistiksel olarak daha düşüktü. ortalama SPLmin, MFZ ve UWQOL’ın ağrı, görünüş, yutma ve çiğneme puan ortalamaları RT almayan grupta RT alan gruptan daha yüksek idi. VHI ve yaşam kalitesi parametreleri arasında bir negatif yönlü bir korelasyon saptandı.

Sonuç: İleri evre larenks kanserlerinde artan cerrahi manüpülasyonlar ve adjuvant RT ihtiyacı hastaların ağrı, ses, konuşma, yutma, çiğneme fonksiyonlarını etkileyerek yaşam kalitesini düşürmektedir. Bu nedenle hastalığın erken tanınıp tedavisinin planlanması oldukça önemlidir. Öznel ses kalitesi arttıkça yaşam kalitesi skorlarının da artmış olması hastaların tedavi sonrası ses terapisine ve psikoterapiye yönlendirilmelerinin önemini bir kez daha göstermektedir. 

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Primary Language en
Subjects Health Care Sciences and Services
Published Date Apr 2017
Journal Section Original Research
Authors

Author: Medine Kara
Institution: Department of Otolaryngology, Çanakkale Onsekiz Mart University, Çanakkale
Country: Turkey


Author: Hülya Ertekin
Institution: Department of Psychiatry, Çanakkale Onsekiz Mart University, Çanakkale
Country: Turkey


Author: Başak Şahin
Institution: Department of Psychiatry, Çanakkale Onsekiz Mart University, Çanakkale
Country: Turkey


Author: Sibel Cevizci
Institution: Department of Public Health, Çanakkale Onsekiz Mart University, Çanakkale
Country: Turkey


Author: Fevzi Sefa Dereköy
Institution: Department of Otolaryngology, Çanakkale Onsekiz Mart University, Çanakkale
Country: Turkey


Dates

Application Date : October 26, 2016
Acceptance Date : March 30, 2017
Publication Date : April 25, 2017

Bibtex @research article { fppc308837, journal = {Family Practice and Palliative Care}, issn = {2458-8865}, eissn = {2459-1505}, address = {}, publisher = {SERNEV}, year = {2017}, volume = {2}, pages = {9 - 16}, doi = {10.22391/920.308837}, title = {Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer}, key = {cite}, author = {Kara, Medine and Ertekin, Hülya and Şahin, Başak and Cevizci, Sibel and Dereköy, Fevzi Sefa} }
APA Kara, M , Ertekin, H , Şahin, B , Cevizci, S , Dereköy, F . (2017). Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer. Family Practice and Palliative Care , 2 (1) , 9-16 . DOI: 10.22391/920.308837
MLA Kara, M , Ertekin, H , Şahin, B , Cevizci, S , Dereköy, F . "Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer". Family Practice and Palliative Care 2 (2017 ): 9-16 <http://www.fppc.com.tr/en/issue/28840/308837>
Chicago Kara, M , Ertekin, H , Şahin, B , Cevizci, S , Dereköy, F . "Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer". Family Practice and Palliative Care 2 (2017 ): 9-16
RIS TY - JOUR T1 - Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer AU - Medine Kara , Hülya Ertekin , Başak Şahin , Sibel Cevizci , Fevzi Sefa Dereköy Y1 - 2017 PY - 2017 N1 - doi: 10.22391/920.308837 DO - 10.22391/920.308837 T2 - Family Practice and Palliative Care JF - Journal JO - JOR SP - 9 EP - 16 VL - 2 IS - 1 SN - 2458-8865-2459-1505 M3 - doi: 10.22391/920.308837 UR - https://doi.org/10.22391/920.308837 Y2 - 2017 ER -
EndNote %0 Family Practice and Palliative Care Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer %A Medine Kara , Hülya Ertekin , Başak Şahin , Sibel Cevizci , Fevzi Sefa Dereköy %T Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer %D 2017 %J Family Practice and Palliative Care %P 2458-8865-2459-1505 %V 2 %N 1 %R doi: 10.22391/920.308837 %U 10.22391/920.308837
ISNAD Kara, Medine , Ertekin, Hülya , Şahin, Başak , Cevizci, Sibel , Dereköy, Fevzi Sefa . "Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer". Family Practice and Palliative Care 2 / 1 (April 2017): 9-16 . https://doi.org/10.22391/920.308837
AMA Kara M , Ertekin H , Şahin B , Cevizci S , Dereköy F . Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer. Fam Pract Palliat Care. 2017; 2(1): 9-16.
Vancouver Kara M , Ertekin H , Şahin B , Cevizci S , Dereköy F . Correlation of voice and quality of life with adjuvant radiotherapy in patients with larynx cancer. Family Practice and Palliative Care. 2017; 2(1): 16-9.