Abstract
Giriş: Lenfadenopati çocukluk döneminde sık karşılaşılan bir klinik problemdir.Tüberküloz lenfadeniti gelişmekte olan ülkelerde
çocuklarda görülen periferal adenopatinin belirgin bir nedenidir. Tüberküloz lenfadenopati akciğer dışı tüberkülozun en sık görülen
bulgusudur. Bu makalede, servikal lenf nodlarında mikobakteriyel enfeksiyon saptanan beş çocuk olgu sunuldu.
Vaka Sunumu: İlk vaka servikal ve aksiller bölgelerdeki ağrısız şişlikle başvurdu ve alınan lenf nodunun patolojik incelemesinde
nekrotizan granülomatöz lenfadenit görüldü. İkinci vaka, iki aydır devam eden sağ servikal bölgede ağrısız şişlik ve karın ağrısı öyküsü
ile görüldü ve lenf nodu kültüründe Mikobakterium tüberkülozis (MTB) üredi. Üçüncü vaka ağrısız servikal kitle ile başvurdu ve balgam
kültürü MTB için pozitif bulundu. Dördüncü vaka, son 6 ay içinde fistülize olan şişlik öyküsü ile başvurdu ve lenf nodu kültürü MTB
için pozitif bulundu. Beşinci vaka, üst gingival mukozada ağrısız şişlik ile başvurdu ve alınan len nodu kronik granülomatöz
inflamasyonla uyumlu idi.
Sonuç: Geniş servikal lenf nodları gibi dokuların patolojik ve mikrobiyolojik incelemeleri tüberküloz infeksiyonlarının tanısı için
değerlendirilmelidir
References
- Handa U, Mundi I, Mohan S. Nodal tuberculosis revisited: a review. Journal of infection in developing countries. 2012;6(1):6-12.
- Denkinger CM, Schumacher SG, Boehme CC, Dendukuri N, Pai M, Steingart KR. Xpert MTB/RIF assay for the diagnosis of extrapulmonary tuberculosis: a systematic review and meta-analysis. The European respiratory journal. 2014;44(2):435-46.
- Daley P, Thomas S, Pai M. Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a systematic review. The international journal of tuberculosis and lung disease: the official journal of the International Union against Tuberculosis and Lung Disease. 2007;11(11):1166-76.
- Assael R, Cervantes J, Barrera G. Smears and cultures for diagnosis of pulmonary tuberculosis in an asymptomatic immigrant population. International journal of general medicine. 2013;6:777-9.
- Sakae T, Yamamoto H. Crystals and calcification patterns in two lymph node calcifications. Journal of oral pathology. 1987;16(9):456-62.
- Fontanilla JM, Barnes A, von Reyn CF. Current diagnosis and management of peripheral tuberculous lymphadenitis. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2011;53(6):555-62.
Abstract
Introduction: Lymphadenopathy is a common clinical problem in pediatric age group. Tuberculous lymphadenopathy is a prominent cause of peripheral adenopathy amongst children in the developing countries. Tuberculous lymphadenitis is among the most frequent presentations of extrapulmonary tuberculosis. In this article, we presented five pediatric cases with mycobacterial infection detected in cervical lymph nodes.
Case Presentation: First case admitted with a painless swelling in cervical and axillar regions and pathologic examination of the extirpated lymph node showed necrotizing granulomatous lymphadenitis. Second case presented with two months history of abdominal pain and painless swelling of right cervical region and Mycobacterium tuberculosis (MTB) was grown in culture from the lymph node. Third case admitted with a painless cervical mass, her sputum was found positive for MTB. Fourth case was admitted with one year history of swelling that became fistulized in 6 months and lymph node culture was found positive for MTB. Fifth case, admitted with a painful swelling in left upper gingival mucosa and extirpated lymph node showed chronic granulomatous inflammation.
Conclusion: Pathological and microbiological examination of tissues such as cervical enlarged lymph nodes should be evaluated for diagnosis of tuberculous infections.
References
- Handa U, Mundi I, Mohan S. Nodal tuberculosis revisited: a review. Journal of infection in developing countries. 2012;6(1):6-12.
- Denkinger CM, Schumacher SG, Boehme CC, Dendukuri N, Pai M, Steingart KR. Xpert MTB/RIF assay for the diagnosis of extrapulmonary tuberculosis: a systematic review and meta-analysis. The European respiratory journal. 2014;44(2):435-46.
- Daley P, Thomas S, Pai M. Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a systematic review. The international journal of tuberculosis and lung disease: the official journal of the International Union against Tuberculosis and Lung Disease. 2007;11(11):1166-76.
- Assael R, Cervantes J, Barrera G. Smears and cultures for diagnosis of pulmonary tuberculosis in an asymptomatic immigrant population. International journal of general medicine. 2013;6:777-9.
- Sakae T, Yamamoto H. Crystals and calcification patterns in two lymph node calcifications. Journal of oral pathology. 1987;16(9):456-62.
- Fontanilla JM, Barnes A, von Reyn CF. Current diagnosis and management of peripheral tuberculous lymphadenitis. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2011;53(6):555-62.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | February 9, 2016 |
| Submission Date | February 9, 2016 |
| Acceptance Date | March 30, 2016 |
| Published in Issue | Year 2016Volume: 1 Issue: 1 |
