Year 2020, Volume 5 , Issue 2, Pages 31 - 35 2020-05-14

Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases
Talk plörodezisin malign ve paramalign plevral efüzyonda etkinliği: 61 olgunun retrospektif analizi

Hasan Oğuz KAPICIBAŞI [1]


Introduction: Malignant-paramalignant effusions are common after malignancies. Treatment of malign-paramalignant pleural effusion is directed towards palliation of symptoms and improvement in quality of life. Chemical pleurodesis has been widely used to control malignant and para-malignant pleural effusion. The present study aims to reveal the effects of chemical pleurodesis on malignant and paramalignant pleural effusions commonly coexisting with malignant diseases.
Methods: 61 patients were retrospectively examined between October 2017 and December 2019. Drainage with 8F intrapleural catheter and chemical pleurodesis (sterile talc powder) were employed in 61 patients with malignant and/or paramalignant effusion. The patient group consisted of patients treated at the thoracic surgery service or consulted from other services. The patients demographics and data on their operated side (left/right), recurrence rate, length of postoperative hospital stay, and complications were extracted from their files.
Results: The sample consisted of 48 male (78.6%) and 13 female (21.3%) patients. The patients were between 22 and 82 years and the average age was 60.0 ± 13.2 years. 33 patients (54.0%) were operated on the right side, while 7 (11.4%) and 21 (34.4%) were operated bilaterally or on the left side, respectively. The most common cause of malignant and paramalignant pleural effusion was found to be lung cancer, accounting for 38 (62.2%) of the patients. Postoperative recurrence was observed in 15 (24.5%) patients. The ‎Mann-Whitney U test was used for skewed variables, and the Chi-Square test (or Fisher’s exact test) was used for ‎categorical variables. No significant difference was observed in terms of surgery side (p=0.676), gender (p=0.156) and malignant disease (p=0.979).The average length of hospital stay was 5.3 days.
Conclusions: The primary principle is to control the symptoms by removing the intrapleural effusion in the cases of malignant and paramalignant effusions. When recurrence rates were evaluated, intrapleural catheter drainage and chemical pleurodesis are an effective and safe method in selected patients.

Giriş: Malign ve paramalign effüzyonlar malignitelerden sonra yaygındır. Malign-paramalign plevral efüzyon tedavisi semptomların hafifletilmesine ve yaşam kalitesinin iyileştirilmesine yöneliktir. Kimyasal plörodez, malign ve paramalign plevral efüzyonu kontrol etmek için yaygın olarak kullanılmaktadır. Bu çalışmada malign hastalıklarla yaygın olarak birliktelik gösteren malign-paramalign plevral efüzyonlarda kimyasal plörodezisin etkisini saptamayı amaçladık.
Yöntem: 2017 Ekim ve 2019 Aralık yılları arasında 61 hasta retropektif olarak değerlendirilmiştir. 61 hastaya tarafımızdan malign ve/veya paramalign efüzyon nedeniyle 8F intraplevral kateter ile drenaj ve kimyasal plörodezis (steril talk pudrası) uygulandı. Hastalar göğüs cerrahisi servisinde tedavi edilen veya diğer servislerden konsultayon yapılan hastalardan oluşmaktaydı. Hastaların demografik verileri, operasyon tarafı (sol/sağ), rekürrens oranı, postoperatif hastanede kalış süresi ve komplikasyonları dosyalardan değerlerlendirildi.
Bulgular: Kırksekiz hasta (%78,6) erkek iken, 13 (%21,3) hasta kadındı. Yaş ortalaması 60,0 ± 13,2 olup yaş aralığı 22-82 yaş idi. 33 (%54,0) hasta sağ tarafından opere edilirken 7 (%11,4) hasta bilateral, 21 (%34,4) hasta sol tarafından opere edildi. En sık malign-paramalign plevral efüzyon nedeni 38 (%62,2) hasta ile akciğer kanseriydi. Postoperatif rekürrens 15 (%24,5) hastada izlendi. Niceliksel değişkenler için Mann-Whitney U testi ve kategorik değişkenler için Chi-Square testi (veya Fisher’ın exact test) kullanıldı. Cerrahi taraf (p = 0,676), cinsiyet (p = 0,156) ve malign hastalık (p = 0,979) açısından anlamlı fark gözlenmedi. Hastaneden ortalama yatış süresi 5,3 gündü.
Sonuç: Malign-paramalign efüzyonlarda intraplevral efüzyonun boşaltılarak semptomların kontrol altına alınması ana prensiptir. Rekürrens oranları değerlendirildiğinde, intraplevral kateter ile drenaj ve kimyasal plörodezis, seçilmiş hastalarda etkili ve güvenli bir yöntemdir.

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Primary Language en
Subjects Surgery
Published Date 2020
Journal Section Original Research
Authors

Orcid: 0000-0001-7275-1039
Author: Hasan Oğuz KAPICIBAŞI (Primary Author)
Institution: Canakkale Onsekiz Mart University, Faculty of Medicine, Department of Thoracic Surgery, Canakkale
Country: Turkey


Dates

Application Date : January 13, 2020
Acceptance Date : March 8, 2020
Publication Date : May 14, 2020

Bibtex @research article { fppc674215, journal = {Family Practice and Palliative Care}, issn = {2458-8865}, eissn = {2459-1505}, address = {}, publisher = {SERNEV}, year = {2020}, volume = {5}, pages = {31 - 35}, doi = {10.22391/fppc.674215}, title = {Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases}, key = {cite}, author = {Kapıcıbaşı, Hasan Oğuz} }
APA Kapıcıbaşı, H . (2020). Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases . Family Practice and Palliative Care , 5 (2) , 31-35 . DOI: 10.22391/fppc.674215
MLA Kapıcıbaşı, H . "Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases" . Family Practice and Palliative Care 5 (2020 ): 31-35 <http://www.fppc.com.tr/en/pub/issue/54329/674215>
Chicago Kapıcıbaşı, H . "Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases". Family Practice and Palliative Care 5 (2020 ): 31-35
RIS TY - JOUR T1 - Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases AU - Hasan Oğuz Kapıcıbaşı Y1 - 2020 PY - 2020 N1 - doi: 10.22391/fppc.674215 DO - 10.22391/fppc.674215 T2 - Family Practice and Palliative Care JF - Journal JO - JOR SP - 31 EP - 35 VL - 5 IS - 2 SN - 2458-8865-2459-1505 M3 - doi: 10.22391/fppc.674215 UR - https://doi.org/10.22391/fppc.674215 Y2 - 2020 ER -
EndNote %0 Family Practice and Palliative Care Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases %A Hasan Oğuz Kapıcıbaşı %T Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases %D 2020 %J Family Practice and Palliative Care %P 2458-8865-2459-1505 %V 5 %N 2 %R doi: 10.22391/fppc.674215 %U 10.22391/fppc.674215
ISNAD Kapıcıbaşı, Hasan Oğuz . "Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases". Family Practice and Palliative Care 5 / 2 (May 2020): 31-35 . https://doi.org/10.22391/fppc.674215
AMA Kapıcıbaşı H . Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases. Fam Pract Palliat Care. 2020; 5(2): 31-35.
Vancouver Kapıcıbaşı H . Efficacy of talc pleurodesis for malignant and paramalignant pleural effusion: a retrospective analysis of 61 cases. Family Practice and Palliative Care. 2020; 5(2): 31-35.