Araştırma Makalesi
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Akut böbrek hasarı olan hastalarda serum düzeltilmiş ve iyonize kalsiyum seviyelerinin karşılaştırılması

Yıl 2021, Cilt 6, Sayı 2, 77 - 80, 05.05.2021
https://doi.org/10.22391/fppc.854694

Öz

Giriş: Hastaneye yatırılan hastalarda akut böbrek hasarı (ABH) sık olarak görülmektedir (%1,92). ABH’lı hastalarda serum düzeltilmiş ve iyonize kalsiyum düzeylerinin acil hemodiyalizi öngörmedeki etkisi bilinmemektedir. Bu çalışmada acil serviste ABH tanısı alan hastalarda serum düzeltilmiş ve iyonize kalsiyum düzeylerini karşılaştırmayı amaçladık.

Yöntem: Çalışmamız retrospektif olarak planlandı. Grup 1: En az bir kez acil hemodiyaliz seansı alan ABH hastaları. Grup 2: Hemodiyalize girmeyen AKIN evre 1-3 olan hastalar. Hastaların başvuru anında serum düzeltilmiş ve iyonize kalsiyum, kreatinin ve albümin değerleri incelendi. Çalışmanın tüm verileri SPSS 19.0 ile kaydedildi. İstatistiksel anlamlılık için p <0,050 kabul edildi.

Bulgular: Serum düzeltilmiş kalsiyum düzeylerinin ortalaması grup 1'de grup 2'ye göre daha düşüktü ve fark istatistiksel olarak anlamlıydı (p <0,001). Kan gazındaki ortalama iyonize kalsiyum seviyeleri grup 1'de grup 2'ye göre daha düşüktü ve fark istatistiksel olarak anlamlıydı (p = 0,002).

Sonuç: ABH hastalarında acil hemodiyalizin öngörülmesinde serum düzeltilmiş ve iyonize kalsiyum düzeyleri faydalı olabilir.

Kaynakça

  • 1. Liangos O, Wald R, O’Bell JW, Price L, Pereira BJ, Jaber BL. Epidemiology and outcomes of acute renal failure in hospitalized patients: a national survey. Clin J Am Soc Nephrol 2006; 1(1):43–51. https://doi.org/10.2215/CJN.00220605
  • 2. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16(11):3365–70. https://doi.org/10.1681/ASN.2004090740
  • 3. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11(2): R31. https://doi.org/10.1186/cc5713
  • 4. Kellum JA, Mehta RL, Levin A, Molitoris BA, Wranock DG, Shah SV, et al. Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process. Clin J Am Soc Nephrol. 2008;3(3):887-94. https://doi.org/10.2215/CJN.04891107
  • 5. Tuglular SZ. [Acute Problems in Calcium and Phosphorus in Renal Disease Setting] (in Turkish). Turk Clin J Nephrol-Special Topics 2010;3(1):50-5.
  • 6. Thongprayoon C, Cheungpasitporn W, Mao MA, Sakhuja A, Erickson S. Admission Calcium levels and risk of acute kidney injury in hospitalised patients. Int J Clin Pract 2018;72(4):e13057. https://doi.org/10.1111/ijcp.13057
  • 7. Khwaja A. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int. Supplements 2012;2:1-138. https://doi.org/10.1038/kisup.2012.6
  • 8. Assadi F. Hypercalcemia: an evidence-based approach to clinical cases. Iran J Kidney Dis 2009;3(2):71-9. https://pubmed.ncbi.nlm.nih.gov/19395781/
  • 9. Higaki M, Tanemoto M, Shiraishi T, Taniguchi K, Fujigaki Y, Uchida S. Acute Kidney Injury Facilitates Hypocalcemia by Exacerbating the Hyperphosphatemic Effect of Muscle Damage in Rhabdomyolysis. Nephron 2015;131(1):11-6. https://doi.org/10.1159/000437391
  • 10. Akman C, Cakır DÜ, Bakirdogen S, Balcı S.The effect of serum calcium levels on uremic encephalopathy in patients with acute kidney injury in the emergency department. Medicina 2019;55(5):204. https://doi.org/10.3390/medicina55050204
  • 11. Bellomo R, Kellum JA, Ronco C, Wald R, Martensonn J, Maiden M, et al. Acute kidney injury in sepsis. Intensive Care Med 2017; 43(6):816-28. https://doi.org/10.1007/s00134-017-4755-7
  • 12. Shao M, Wang S, Parameswaran PK. Hypoalbuminemia: a risk factor for acute kidney injury development and progression to chronic kidney disease in critically ill patients. Int Urol Nephrol 2017;49(2):295-302. https://doi.org/10.1007/s11255-016-1453-2
  • 13. Wiedermann CJ, Wiedermann W, Joannidis M. Causal relationship between hypoalbuminemia and acute kidney injury. World J Nephrol. 2017;6(4):176-87. https://doi.org/10.5527/wjn.v6.i4.176
  • 14. Wiedermann CJ, Joannidis M. Nephroprotective Potential of Human Albumin Infusion: A Narrative Review. Gastroenterol Res Pract 2015; 912939:8 . http://dx.doi.org/10.1155/2015/912839

Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury

Yıl 2021, Cilt 6, Sayı 2, 77 - 80, 05.05.2021
https://doi.org/10.22391/fppc.854694

Öz

Introduction: Acute kidney injury (AKI) is common in hospitalized patients (1.92%). The effect of serum corrected and ionized calcium levels in predicting emergency hemodialysis in patients with AKI is unknown. In this study, we aimed to compare serum corrected and ionized calcium levels in patients who were diagnosed with AKI in the emergency service.

Methods: Our study was planned retrospectively. Group 1: Patients with AKI who underwent at least one session of emergency hemodialysis. Group 2: The patients with AKIN stage 1-3 who did not undergo hemodialysis. Serum corrected and ionized calcium, creatinine and albumin values of the patients at the time of admission were analyzed. All data of the study were recorded by SPSS 19.0. For statistical significance, p <0.050 was accepted.

Results: The mean serum corrected calcium levels were lower in group 1 than in group 2, and the difference was statistically significant (p <0.001). The mean ionized calcium levels in blood gas were lower in group 1 than in group 2, and the difference was statistically significant (p = 0.002).

Conclusions: Serum corrected, and ionized calcium levels can be useful in predicting emergency hemodialysis in patients with AKI.

Kaynakça

  • 1. Liangos O, Wald R, O’Bell JW, Price L, Pereira BJ, Jaber BL. Epidemiology and outcomes of acute renal failure in hospitalized patients: a national survey. Clin J Am Soc Nephrol 2006; 1(1):43–51. https://doi.org/10.2215/CJN.00220605
  • 2. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16(11):3365–70. https://doi.org/10.1681/ASN.2004090740
  • 3. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11(2): R31. https://doi.org/10.1186/cc5713
  • 4. Kellum JA, Mehta RL, Levin A, Molitoris BA, Wranock DG, Shah SV, et al. Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process. Clin J Am Soc Nephrol. 2008;3(3):887-94. https://doi.org/10.2215/CJN.04891107
  • 5. Tuglular SZ. [Acute Problems in Calcium and Phosphorus in Renal Disease Setting] (in Turkish). Turk Clin J Nephrol-Special Topics 2010;3(1):50-5.
  • 6. Thongprayoon C, Cheungpasitporn W, Mao MA, Sakhuja A, Erickson S. Admission Calcium levels and risk of acute kidney injury in hospitalised patients. Int J Clin Pract 2018;72(4):e13057. https://doi.org/10.1111/ijcp.13057
  • 7. Khwaja A. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int. Supplements 2012;2:1-138. https://doi.org/10.1038/kisup.2012.6
  • 8. Assadi F. Hypercalcemia: an evidence-based approach to clinical cases. Iran J Kidney Dis 2009;3(2):71-9. https://pubmed.ncbi.nlm.nih.gov/19395781/
  • 9. Higaki M, Tanemoto M, Shiraishi T, Taniguchi K, Fujigaki Y, Uchida S. Acute Kidney Injury Facilitates Hypocalcemia by Exacerbating the Hyperphosphatemic Effect of Muscle Damage in Rhabdomyolysis. Nephron 2015;131(1):11-6. https://doi.org/10.1159/000437391
  • 10. Akman C, Cakır DÜ, Bakirdogen S, Balcı S.The effect of serum calcium levels on uremic encephalopathy in patients with acute kidney injury in the emergency department. Medicina 2019;55(5):204. https://doi.org/10.3390/medicina55050204
  • 11. Bellomo R, Kellum JA, Ronco C, Wald R, Martensonn J, Maiden M, et al. Acute kidney injury in sepsis. Intensive Care Med 2017; 43(6):816-28. https://doi.org/10.1007/s00134-017-4755-7
  • 12. Shao M, Wang S, Parameswaran PK. Hypoalbuminemia: a risk factor for acute kidney injury development and progression to chronic kidney disease in critically ill patients. Int Urol Nephrol 2017;49(2):295-302. https://doi.org/10.1007/s11255-016-1453-2
  • 13. Wiedermann CJ, Wiedermann W, Joannidis M. Causal relationship between hypoalbuminemia and acute kidney injury. World J Nephrol. 2017;6(4):176-87. https://doi.org/10.5527/wjn.v6.i4.176
  • 14. Wiedermann CJ, Joannidis M. Nephroprotective Potential of Human Albumin Infusion: A Narrative Review. Gastroenterol Res Pract 2015; 912939:8 . http://dx.doi.org/10.1155/2015/912839

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Yayınlanma Tarihi Jun 2021
Bölüm Araştırma Makalesi (Original Article)
Yazarlar

Canan AKMAN> (Sorumlu Yazar)
Canakkale Onsekiz Mart University, School of Medicine, Department of Emergency Medicine, Canakkale
0000-0002-3427-5649
Türkiye


Serkan BAKİRDOGEN>
Canakkale Onsekiz Mart Unıversty, School of Medicine, Department of Nephrology, Canakkale
0000-0002-3448-0490
Türkiye


Murat DAŞ>
Canakkale Onsekiz Mart University, School of Medicine, Department of Emergency Medicine, Canakkale
0000-0003-0893-6084
Türkiye


Serdal BALCI>
Sirnak State Hospital, Emergency Service, Sirnak
0000-0002-5795-0651
Türkiye


Okyanus Necdet AYKAN>
Kastamonu State Hospital
0000-0001-7965-125X
Türkiye

Yayımlanma Tarihi 5 Mayıs 2021
Başvuru Tarihi 5 Ocak 2021
Kabul Tarihi 2 Nisan 2021
Yayınlandığı Sayı Yıl 2021, Cilt 6, Sayı 2

Kaynak Göster

Bibtex @araştırma makalesi { fppc854694, journal = {Family Practice and Palliative Care}, issn = {2458-8865}, eissn = {2459-1505}, address = {}, publisher = {Yusuf Haydar ERTEKİN}, year = {2021}, volume = {6}, number = {2}, pages = {77 - 80}, doi = {10.22391/fppc.854694}, title = {Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury}, key = {cite}, author = {Akman, Canan and Bakirdogen, Serkan and Daş, Murat and Balcı, Serdal and Aykan, Okyanus Necdet} }
APA Akman, C. , Bakirdogen, S. , Daş, M. , Balcı, S. & Aykan, O. N. (2021). Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury . Family Practice and Palliative Care , 6 (2) , 77-80 . DOI: 10.22391/fppc.854694
MLA Akman, C. , Bakirdogen, S. , Daş, M. , Balcı, S. , Aykan, O. N. "Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury" . Family Practice and Palliative Care 6 (2021 ): 77-80 <http://www.fppc.com.tr/tr/pub/issue/62141/854694>
Chicago Akman, C. , Bakirdogen, S. , Daş, M. , Balcı, S. , Aykan, O. N. "Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury". Family Practice and Palliative Care 6 (2021 ): 77-80
RIS TY - JOUR T1 - Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury AU - Canan Akman , Serkan Bakirdogen , Murat Daş , Serdal Balcı , Okyanus Necdet Aykan Y1 - 2021 PY - 2021 N1 - doi: 10.22391/fppc.854694 DO - 10.22391/fppc.854694 T2 - Family Practice and Palliative Care JF - Journal JO - JOR SP - 77 EP - 80 VL - 6 IS - 2 SN - 2458-8865-2459-1505 M3 - doi: 10.22391/fppc.854694 UR - https://doi.org/10.22391/fppc.854694 Y2 - 2021 ER -
EndNote %0 Family Practice and Palliative Care Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury %A Canan Akman , Serkan Bakirdogen , Murat Daş , Serdal Balcı , Okyanus Necdet Aykan %T Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury %D 2021 %J Family Practice and Palliative Care %P 2458-8865-2459-1505 %V 6 %N 2 %R doi: 10.22391/fppc.854694 %U 10.22391/fppc.854694
ISNAD Akman, Canan , Bakirdogen, Serkan , Daş, Murat , Balcı, Serdal , Aykan, Okyanus Necdet . "Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury". Family Practice and Palliative Care 6 / 2 (Mayıs 2021): 77-80 . https://doi.org/10.22391/fppc.854694
AMA Akman C. , Bakirdogen S. , Daş M. , Balcı S. , Aykan O. N. Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury. Fam Pract Palliat Care. 2021; 6(2): 77-80.
Vancouver Akman C. , Bakirdogen S. , Daş M. , Balcı S. , Aykan O. N. Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury. Family Practice and Palliative Care. 2021; 6(2): 77-80.
IEEE C. Akman , S. Bakirdogen , M. Daş , S. Balcı ve O. N. Aykan , "Comparison of serum corrected and ionized calcium levels in patients with acute kidney injury", Family Practice and Palliative Care, c. 6, sayı. 2, ss. 77-80, May. 2021, doi:10.22391/fppc.854694

AİLE HEKİMLİĞİ ve PALYATİF BAKIM       ISSN 2458-8865       E-ISSN 2459-1505

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